Publications by authors named "Debbie Callaghan"

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Synthesis of α,ε-,'-Di-stearoyl Lysine-Derived Amide Lipids and Their Application to Liposome Formulation: Incorporation of Lipid A-Ligand for Bacterial Targeting and Sialic Acid for Phagocytosis Resistance.
Dean Williams, Alyssa McAdorey, Eric Lei, Greg Beaudoin, Binbing Ling, Debbie Callaghan

Int J Mol Sci· September 2025

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A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models.
Marzia Martina, Umberto Banderali, Alvaro Yogi, Mehdi Arbabi Ghahroudi, Hong Liu, Debbie Callaghan

Adv Sci (Weinh)· October 2024

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Apolipoprotein E Isoforms Differentially Regulate Alzheimer's Disease and Amyloid-β-Induced Inflammatory Response in vivo and in vitro.
Evan Dorey, Michelle Bamji-Mirza, Dema Najem, Yan Li, Hong Liu, Debbie Callaghan

J Alzheimers Dis· February 2018

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Stimulation of insulin signaling and inhibition of JNK-AP1 activation protect cells from amyloid-β-induced signaling dysregulation and inflammatory response.
Michelle Bamji-Mirza, Debbie Callaghan, Dema Najem, Shanshan Shen, Mohamed Shaad Hasim

J Alzheimers Dis· October 2014

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Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging.
Wandong Zhang, Huaqi Xiong, Debbie Callaghan, Hong Liu, Aimee Jones

Fluids Barriers CNS· February 2013

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Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg-SwDI transgenic mice.
Yu Zeng, Debbie Callaghan, Huaqi Xiong, Ze Yang, Peilin Huang

J Neurochem· July 2012

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Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer's disease.
Huaqi Xiong, Debbie Callaghan, Jolanta Wodzinska, Jiejing Xu, Maryna Premyslova

Neurosci Bull· August 2011

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ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease.
Shanshan Shen, Debbie Callaghan, Camille Juzwik, Huaqi Xiong, Peilin Huang

J Neurochem· September 2010

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Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
Vanja Vukic, Debbie Callaghan, Douglas Walker, Lih-Fen Lue, Qing Yan Liu

Neurobiol Dis· April 2009

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ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.
Huaqi Xiong, Debbie Callaghan, Aimee Jones, Jianying Bai, Ingrid Rasquinha

J Neurosci· April 2009

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Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production.
Huaqi Xiong, Debbie Callaghan, Aimee Jones, Douglas G Walker, Lih-Fen Lue

Neurobiol Dis· March 2008

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Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes.
Jelena Mojsilovic-Petrovic, Debbie Callaghan, Hong Cui, Clare Dean, Danica B Stanimirovic

J Neuroinflammation· May 2007

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Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures.
Wandong Zhang, Jelena-Mojsilovic Petrovic, Debbie Callaghan, Aimee Jones, Hong Cui

J Neuroimmunol· May 2006

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