Publications by authors named "Debbie Clements"

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Extracellular Matrix Deposition Drives Disease Progression and Reduces Rapamycin Response in LAM.
Debbie Clements, Roya Babaei-Jadidi, Jan Johnson, Suzanne Miller, Niraj Shah

Eur Respir J· December 2025

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mTOR dysregulation induces IL-6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis.
Roya Babaei-Jadidi, Debbie Clements, Yixin Wu, Ken Chen, Suzanne Miller

Nat Commun· October 2025

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Cross talk between LAM cells and fibroblasts may influence alveolar epithelial cell behavior in lymphangioleiomyomatosis.
Debbie Clements, Suzanne Miller, Roya Babaei-Jadidi, Mike Adam, S Steven Potter

Am J Physiol Lung Cell Mol Physiol· February 2022

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Mast-Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis.
Roya Babaei-Jadidi, Arundhati Dongre, Suzanne Miller, Marcos Castellanos Uribe, Ian D Stewart, Debbie Clements

Am J Respir Crit Care Med· August 2021

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Evolution of lung pathology in lymphangioleiomyomatosis: associations with disease course and treatment response.
Suzanne Miller, Iain D Stewart, Debbie Clements, Irshad Soomro, Roya Babaei-Jadidi

J Pathol Clin Res· July 2020

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Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis.
Christopher J Philp, Ivonne Siebeke, Debbie Clements, Suzanne Miller, Anthony Habgood

Am J Respir Cell Mol Biol· May 2018

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Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Arundhati Dongre, Debbie Clements, Andrew J Fisher, Simon R Johnson

Am J Pathol· August 2017

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Matrix Metalloproteinase-1 Activation Contributes to Airway Smooth Muscle Growth and Asthma Severity.
Shams-Un-Nisa Naveed, Debbie Clements, David J Jackson, Christopher Philp, Charlotte K Billington

Am J Respir Crit Care Med· April 2017

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Wild type mesenchymal cells contribute to the lung pathology of lymphangioleiomyomatosis.
Debbie Clements, Arundhati Dongre, Vera P Krymskaya, Simon R Johnson

PLoS One· April 2016

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Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma.
Natasha K Rogers, Debbie Clements, Arundhati Dongre, Tim W Harrison, Dominic Shaw

PLoS One· June 2015

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Designing faculty development to support the evaluation of resident competency in the intrinsic CanMEDS roles: practical outcomes of an assessment of program director needs.
Derek Puddester, Colla J MacDonald, Debbie Clements, Jane Gaffney, Lorne Wiesenfeld

BMC Med Educ· June 2015

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Effect of doxycycline on proliferation, MMP production, and adhesion in LAM-related cells.
William Y C Chang, Debbie Clements, Simon R Johnson

Am J Physiol Lung Cell Mol Physiol· September 2010

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Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma.
Debbie Clements, Lee J Markwick, Nidhi Puri, Simon R Johnson

J Immunol· August 2010

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Analysis of the oestrogen response in an angiomyolipoma derived xenograft model.
Debbie Clements, Sarah L Asprey, Thomas A McCulloch, Theresa A Morris, Susan A Watson

Endocr Relat Cancer· March 2009

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AtEnsEMBL.
Nick James, Neil Graham, Debbie Clements, Beatrice Schildknecht, Sean May

Methods Mol Biol· January 2009

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Regulation of the Xenopus Xsox17alpha(1) promoter by co-operating VegT and Sox17 sites.
Laura Howard, Maria Rex, Debbie Clements, Hugh R Woodland

Dev Biol· October 2007

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Subcellular distribution of the TSC2 gene product tuberin in human airway smooth muscle cells is driven by multiple localization sequences and is cell-cycle dependent.
Debbie Clements, R John Mayer, Simon R Johnson

Am J Physiol Lung Cell Mol Physiol· January 2007

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VegT induces endoderm by a self-limiting mechanism and by changing the competence of cells to respond to TGF-beta signals.
Debbie Clements, Hugh R Woodland

Dev Biol· June 2003

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Redundant early and overlapping larval roles of Xsox17 subgroup genes in Xenopus endoderm development.
Debbie Clements, Isabelle Cameleyre, Hugh R Woodland

Mech Dev· March 2003

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