Publications by authors named "Deborah A Fraser"

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Recombinant C1q variants modulate macrophage responses but do not activate the classical complement pathway.
Victoria Espericueta, Ayla O Manughian-Peter, Isabelle Bally, Nicole M Thielens, Deborah A Fraser

Mol Immunol· January 2020

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Higher Order Architecture of Designer Peptides Forms Bioinspired 10 nm siRNA Delivery System.
Alicia Gamboa, Selina F Urfano, Katrina Hernandez, Deborah A Fraser, Luladey Ayalew

Sci Rep· November 2019

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Association between chronic organochlorine exposure and immunotoxicity in the round stingray (Urobatis halleri).
Jillian M Sawyna, Weston R Spivia, Kelly Radecki, Deborah A Fraser, Christopher G Lowe

Environ Pollut· April 2017

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Complement Protein C1q Enhances Macrophage Foam Cell Survival and Efferocytosis.
Marc C Pulanco, Jason Cosman, Minh-Minh Ho, Jessica Huynh, Karina Fing, Deborah A Fraser

J Immunol· January 2017

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Transcriptome data and gene ontology analysis in human macrophages ingesting modified lipoproteins in the presence or absence of complement protein C1q.
Minh-Minh Ho, Deborah A Fraser

Data Brief· December 2016

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Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q.
Minh-Minh Ho, Ayla Manughian-Peter, Weston R Spivia, Adam Taylor, Deborah A Fraser

Atherosclerosis· October 2016

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Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins.
Weston Spivia, Patrick S Magno, Patrick Le, Deborah A Fraser

Inflamm Res· October 2014

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Complement, c1q, and c1q-related molecules regulate macrophage polarization.
Suzanne S Bohlson, Sean D O'Conner, Holly Jo Hulsebus, Minh-Minh Ho, Deborah A Fraser

Front Immunol· September 2014

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A dramatic increase of C1q protein in the CNS during normal aging.
Alexander H Stephan, Daniel V Madison, José María Mateos, Deborah A Fraser, Emilie A Lovelett

J Neurosci· August 2013

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Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.
Marie E Benoit, Elizabeth V Clarke, Pedro Morgado, Deborah A Fraser, Andrea J Tenner

J Immunol· June 2012

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Complement activation and cell uptake responses toward polymer-functionalized protein nanocapsules.
Nicholas M Molino, Kateryna Bilotkach, Deborah A Fraser, Dongmei Ren, Szu-Wen Wang

Biomacromolecules· April 2012

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Recombinant membrane-targeted form of CD59 inhibits the growth of choroidal neovascular complex in mice.
Nalini S Bora, Purushottam Jha, Valeriy V Lyzogubov, Sankaranarayanan Kaliappan, Juan Liu, Deborah A Fraser

J Biol Chem· October 2010

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Innate immune proteins C1q and mannan-binding lectin enhance clearance of atherogenic lipoproteins by human monocytes and macrophages.
Deborah A Fraser, Andrea J Tenner

J Immunol· October 2010

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C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production.
Deborah A Fraser, Karntipa Pisalyaput, Andrea J Tenner

J Neurochem· February 2010

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Complement component c1q mediates mitochondria-driven oxidative stress in neonatal hypoxic-ischemic brain injury.
Vadim S Ten, Jun Yao, Veniamin Ratner, Sergey Sosunov, Deborah A Fraser

J Neurosci· February 2010

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C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.
Deborah A Fraser, Amanda K Laust, Edward L Nelson, Andrea J Tenner

J Immunol· November 2009

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Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation.
Ming Li, Rahasson R Ager, Deborah A Fraser, Natalia O Tjokro, Andrea J Tenner

Mol Immunol· June 2008

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Generation of inhibitory NFkappaB complexes and phosphorylated cAMP response element-binding protein correlates with the anti-inflammatory activity of complement protein C1q in human monocytes.
Deborah A Fraser, Meenakshi Arora, Suzanne S Bohlson, Encarnacion Lozano, Andrea J Tenner

J Biol Chem· March 2007

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Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions.
Suzanne S Bohlson, Deborah A Fraser, Andrea J Tenner

Mol Immunol· January 2007

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C1q and MBL, components of the innate immune system, influence monocyte cytokine expression.
Deborah A Fraser, Suzanne S Bohlson, Nijole Jasinskiene, Nenoo Rawal, Gail Palmarini

J Leukoc Biol· July 2006

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Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo.
Deborah A Fraser, Claire L Harris, Anwen S Williams, Masashi Mizuno, Sean Gallagher

J Biol Chem· December 2003

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Bacterial expression and membrane targeting of the rat complement regulator Crry: a new model anticomplement therapeutic.
Deborah A Fraser, Claire L Harris, Richard A G Smith, B Paul Morgan

Protein Sci· October 2002

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