Publications by authors named "Deborah A Shear"

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Supra-Prophylactic Doses of Enoxaparin Reduces Fibrin Deposition Without Exacerbation of Intracerebral Hemorrhage in a Rat Model of Penetrating Traumatic Brain Injury.
Zachary S Bailey, Anke H Scultetus, Alexandru Korotcov, Ping Wang, Xiaofang Yang, Deborah A Shear

J Neurotrauma· January 2025

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Time Course of Mitochondrial Antioxidant Markers in a Preclinical Model of Severe Penetrating Traumatic Brain Injury.
Sudeep Musyaju, Hiren R Modi, Deborah A Shear, Anke H Scultetus, Jignesh D Pandya

Int J Mol Sci· January 2025

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Intravenous Administration of Anti-CD47 Antibody Augments Hematoma Clearance, Mitigates Acute Neuropathology, and Improves Cognitive Function in a Rat Model of Penetrating Traumatic Brain Injury.
Ping Wang, Xiaofang Yang, Fangzhou Yang, Katherine Cardiff, Melonie Houchins, Deborah A Shear

J Neurotrauma· November 2024

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The game changer: UCH-L1 and GFAP-based blood test as the first marketed in vitro diagnostic test for mild traumatic brain injury.
Firas Kobeissy, Rawad Daniel Arja, Jennifer C Munoz, Deborah A Shear, Janice Gilsdorf

Expert Rev Mol Diagn· February 2024

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Intranasal delivery of mitochondria targeted neuroprotective compounds for traumatic brain injury: screening based on pharmacological and physiological properties.
Jignesh D Pandya, Sudeep Musyaju, Hiren R Modi, Starlyn L Okada-Rising, Zachary S Bailey, Deborah A Shear

J Transl Med· February 2024

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Mitochondria-Targeted Antioxidant Therapeutics for Traumatic Brain Injury.
Hiren R Modi, Sudeep Musyaju, Meaghan Ratcliffe, Deborah A Shear, Anke H Scultetus

Antioxidants (Basel)· February 2024

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Revert total protein normalization method offers a reliable loading control for mitochondrial samples following TBI.
Sudeep Musyaju, Hiren R Modi, William J Flerlage, Anke H Scultetus, Deborah A Shear

Anal Biochem· November 2023

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Upregulation of multiple toll-like receptors in ferret brain after blast exposure: Potential targets for treatment.
Manoj Govindarajulu, Mital Y Patel, Donna M Wilder, Jishnu Krishnan, Christina LaValle, Deborah A Shear

Neurosci Lett· July 2023

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Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating traumatic brain injury.
Jignesh D Pandya, Sudeep Musyaju, Hiren R Modi, Ying Cao, William J Flerlage, Deborah A Shear

Free Radic Biol Med· March 2023

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Choice of Whole Blood versus Lactated Ringer's Resuscitation Modifies the Relationship between Blood Pressure Target and Functional Outcome after Traumatic Brain Injury plus Hemorrhagic Shock in Mice.
Benjamin E Zusman, C Edward Dixon, Ruchira M Jha, Vincent A Vagni, Jeremy J Henchir, Deborah A Shear

J Neurotrauma· October 2021

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Kollidon VA64 Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.
Nicole D Osier, Helen M Bramlett, Deborah A Shear, Stefania Mondello, Shaun W Carlson

J Neurotrauma· September 2021

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Time-Course Evaluation of Brain Regional Mitochondrial Bioenergetics in a Pre-Clinical Model of Severe Penetrating Traumatic Brain Injury.
Jignesh D Pandya, Lai Yee Leung, Hye M Hwang, Xiaofang Yang, Ying Deng-Bryant, Deborah A Shear

J Neurotrauma· August 2021

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Multifaceted Benefit of Whole Blood Versus Lactated Ringer's Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice.
Benjamin E Zusman, Patrick M Kochanek, Zachary S Bailey, Lai Yee Leung, Vincent A Vagni, Deborah A Shear

Neurocrit Care· June 2021

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Glibenclamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.
Ruchira M Jha, Stefania Mondello, Helen M Bramlett, C Edward Dixon, Deborah A Shear

J Neurotrauma· March 2021

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Penetrating Ballistic-Like Brain Injury Leads to MicroRNA Dysregulation, BACE1 Upregulation, and Amyloid Precursor Protein Loss in Lesioned Rat Brain Tissues.
Bharani Thangavelu, Bernard S Wilfred, David Johnson, Janice S Gilsdorf, Deborah A Shear

Front Neurosci· September 2020

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Penetrating Traumatic Brain Injury Triggers Dysregulation of Cathepsin B Protein Levels Independent of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid.
Angela M Boutté, Vivian Hook, Bharani Thangavelu, George Anis Sarkis, Brittany N Abbatiello, Deborah A Shear

J Neurotrauma· July 2020

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Dataset of Rat and Human Serum Proteomes Derived from Differential Depletion Strategies prior to Mass Spectrometry.
Bharani Thangavelu, Gary H Kamimori, Janice S Gilsdorf, Deborah A Shear, Angela M Boutté

Data Brief· June 2020

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Human neural stem cell transplant location-dependent neuroprotection and motor deficit amelioration in rats with penetrating traumatic brain injury.
Zhen Hu, Shyam Gajavelli, Markus S Spurlock, Anil Mahavadi, Liz S Quesada, Deborah A Shear

J Trauma Acute Care Surg· April 2020

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Alterations in Peripheral Organs following Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury.
Bernard S Wilfred, Sindhu K Madathil, Katherine Cardiff, Sarah Urankar, Xiaofang Yang, Deborah A Shear

J Neurotrauma· February 2020

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Post-Traumatic Epilepsy and Seizure Susceptibility in Rat Models of Penetrating and Closed-Head Brain Injury.
Xi-Chun M Lu, Jenny Browning, Zhilin Liao, Ying Cao, Weihong Yang, Deborah A Shear

J Neurotrauma· January 2020

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Editorial: Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges.
Stefania Mondello, Anwarul Hasan, Deborah A Shear

Front Neurol· December 2019

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Gut Microbiota as a Therapeutic Target to Ameliorate the Biochemical, Neuroanatomical, and Behavioral Effects of Traumatic Brain Injuries.
Matthew W Rice, Jignesh D Pandya, Deborah A Shear

Front Neurol· August 2019

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Comprehensive Profile of Acute Mitochondrial Dysfunction in a Preclinical Model of Severe Penetrating TBI.
Jignesh D Pandya, Lai Yee Leung, Xiaofang Yang, William J Flerlage, Janice S Gilsdorf, Deborah A Shear

Front Neurol· June 2019

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Differential Effects of Caffeine on Motor and Cognitive Outcomes of Penetrating Ballistic-Like Brain Injury.
Sarah S Sanjakdar, William J Flerlage, Hyun S Kang, Douglas A Napier, Jaqueline R Dougherty, Deborah A Shear

Mil Med· March 2019

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