Publications by authors named "Deborah D Crane"

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Temporal Requirement for Pulmonary Resident and Circulating T Cells during Virulent Infection.
Lydia M Roberts, Tara D Wehrly, Robin M Ireland, Deborah D Crane, Dana P Scott

J Immunol· August 2018

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The Ability to Acquire Iron Is Inversely Related to Virulence and the Protective Efficacy of Live Vaccine Strain.
Joshua R Fletcher, Deborah D Crane, Tara D Wehrly, Craig A Martens, Catharine M Bosio

Front Microbiol· April 2018

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Expansion and retention of pulmonary CD4 T cells after prime boost vaccination correlates with improved longevity and strength of immunity against tularemia.
Lydia M Roberts, Tara D Wehrly, Deborah D Crane, Catharine M Bosio

Vaccine· May 2017

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Inclusion of Epitopes That Expand High-Avidity CD4+ T Cells Transforms Subprotective Vaccines to Efficacious Immunogens against Virulent Francisella tularensis.
Lydia M Roberts, Deborah D Crane, Tara D Wehrly, Joshua R Fletcher, Bradley D Jones

J Immunol· October 2016

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Metabolic Reprogramming of Host Cells by Virulent Francisella tularensis for Optimal Replication and Modulation of Inflammation.
Elliott V Wyatt, Karina Diaz, Amanda J Griffin, Jed A Rasmussen, Deborah D Crane

J Immunol· May 2016

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Successful protection against tularemia in C57BL/6 mice is correlated with expansion of Francisella tularensis-specific effector T cells.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Catharine M Bosio

Clin Vaccine Immunol· January 2015

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Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.
Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio

PLoS One· September 2014

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Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome.
Deborah D Crane, Timothy J Bauler, Tara D Wehrly, Catharine M Bosio

Front Microbiol· September 2014

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Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor α.
Deborah D Crane, Robin Ireland, Joshua B Alinger, Pamela Small, Catharine M Bosio

Clin Vaccine Immunol· October 2013

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B1a cells enhance susceptibility to infection with virulent Francisella tularensis via modulation of NK/NKT cell responses.
Deborah D Crane, Amanda J Griffin, Tara D Wehrly, Catharine M Bosio

J Immunol· March 2013

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Low dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination.
Dedeke Rockx-Brouwer, Audrey Chong, Tara D Wehrly, Robert Child, Deborah D Crane

PLoS One· December 2012

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Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemia.
Deborah D Crane, Dana P Scott, Catharine M Bosio

PLoS One· August 2012

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Long lived protection against pneumonic tularemia is correlated with cellular immunity in peripheral, not pulmonary, organs.
Rebecca V Anderson, Deborah D Crane, Catharine M Bosio

Vaccine· September 2010

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A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.
Deborah D Crane, Shayna L Warner, Catharine M Bosio

J Immunol· October 2009

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Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.
Tara D Wehrly, Audrey Chong, Kimmo Virtaneva, Dan E Sturdevant, Robert Child, Deborah D Crane

Cell Microbiol· July 2009

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Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.
Laszlo Kari, William M Whitmire, Deborah D Crane, Nathalie Reveneau, John H Carlson

J Immunol· June 2009

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The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.
John H Carlson, William M Whitmire, Deborah D Crane, Luke Wicke, Kimmo Virtaneva

Infect Immun· June 2008

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Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations.
Laszlo Kari, William M Whitmire, John H Carlson, Deborah D Crane, Nathalie Reveneau

J Infect Dis· February 2008

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Chlamydia trachomatis species-specific induction of ezrin tyrosine phosphorylation functions in pathogen entry.
Kena A Swanson, Deborah D Crane, Harlan D Caldwell

Infect Immun· December 2007

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Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum.
David E Nelson, Lacey D Taylor, Jeffrey G Shannon, William M Whitmire, Deborah D Crane

Cell Microbiol· September 2007

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Chlamydia trachomatis polymorphic membrane protein D is a species-common pan-neutralizing antigen.
Deborah D Crane, John H Carlson, Elizabeth R Fischer, Patrik Bavoil, Ru-ching Hsia

Proc Natl Acad Sci U S A· February 2006

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Inhibition of chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes.
David E Nelson, Deborah D Crane, Lacey D Taylor, David W Dorward, Morgan M Goheen

Infect Immun· January 2006

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Chlamydial IFN-gamma immune evasion is linked to host infection tropism.
David E Nelson, Dezso P Virok, Heidi Wood, Christine Roshick, Raymond M Johnson, Deborah D Crane

Proc Natl Acad Sci U S A· July 2005

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Bactericidal activity of first-choice antibiotics against gamma interferon-induced persistent infection of human epithelial cells by Chlamydia trachomatis.
Nathalie Reveneau, Deborah D Crane, Elizabeth Fischer, Harlan D Caldwell

Antimicrob Agents Chemother· May 2005

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Chlamydial infection induces pathobiotype-specific protein tyrosine phosphorylation in epithelial cells.
Dezso P Virok, David E Nelson, William M Whitmire, Deborah D Crane, Morgan M Goheen

Infect Immun· April 2005

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