Publications by authors named "Deborah M Muoio"

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The Failing Heart Relies on Ketone Bodies as a Fuel.
Gregory Aubert, Ola J Martin, Julie L Horton, Ling Lai, Rick B Vega, Teresa C Leone, Timothy Koves, Stephen J Gardell, Marcus Krüger, Charles L Hoppel

Circulation· February 2016

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Ketogenesis mitigates metabolic dysfunction-associated steatotic liver disease through mechanisms that extend beyond fat oxidation.
Eric D Queathem, David B Stagg, Alisa B Nelson, Alec B Chaves, Scott B Crown, Deborah M Muoio

J Clin Invest· June 2025

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Effect of in utero metformin exposure in gestational diabetes mellitus on infant mesenchymal stem cell metabolism.
Ericka M Biagioni, John C Rowe, Sripallavi Yendamuri, Breanna L Wisseman, Donghai Zheng, Deborah M Muoio

Am J Physiol Endocrinol Metab· April 2025

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The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research.
Shaunak Deota, Julie S Pendergast, Ullas Kolthur-Seetharam, Karyn A Esser, Frédéric Gachon, Deborah M Muoio

Nat Metab· March 2025

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Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate.
Eric D Queathem, David Stagg, Alisa Nelson, Alec B Chaves, Scott B Crown, Deborah M Muoio

bioRxiv· December 2024

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Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Ahmad A Cluntun, Joseph R Visker, Jesse N Velasco-Silva, Marisa J Lang, Luis Cedeño-Rosario, Deborah M Muoio

bioRxiv· October 2024

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Translating metabolic and cardiovascular research into effective treatments: What's next?
Juleen R Zierath, Jolanda van der Velden, Ali Javaheri, Anthony Rosenzweig, Deborah M Muoio

Cell· July 2024

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Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding.
Ashley S Williams, Scott B Crown, Scott P Lyons, Timothy R Koves, Rebecca J Wilson, Deborah M Muoio

Cell Metab· February 2024

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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.
Somenath Datta, Brett M Antonio, Nathan H Zahler, Jonathan W Theile, Doug Krafte, Deborah M Muoio

J Clin Invest· January 2024

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Challenges and opportunities in targeting metabolism.
Kivanç Birsoy, Navdeep S Chandel, Sarah-Maria Fendt, Douglas R Green, Xiaoling Li, Deborah M Muoio

Cell Chem Biol· September 2023

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles.
Timothy R Koves, Guo-Fang Zhang, Michael T Davidson, Alec B Chaves, Scott B Crown, Deborah M Muoio

Cell Metab· June 2023

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RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure.
Tsunehisa Yamamoto, Santosh K Maurya, Elizabeth Pruzinsky, Kirill Batmanov, Yang Xiao, Deborah M Muoio

J Clin Invest· May 2023

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Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
Adilson Guilherme, Leslie A Rowland, Nicole Wetoska, Emmanouela Tsagkaraki, Kaltinaitis B Santos, Deborah M Muoio

Cell Rep· May 2023

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Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans.
Rodrigo F Mancilla, Lucas Lindeboom, Lotte Grevendonk, Joris Hoeks, Tim R Koves, Deborah M Muoio

JCI Insight· January 2023

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Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism.
Yvo J M Op den Kamp, Anne Gemmink, Marlies de Ligt, Bas Dautzenberg, Esther Kornips, Deborah M Muoio

Mol Metab· December 2022

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Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities.
Maria J Torres, Xu Zhang, Dorothy H Slentz, Timothy R Koves, Hailee Patel, Deborah M Muoio

iScience· October 2022

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Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis.
Chao Liang, Shan Zhang, David Robinson, Matthew Vander Ploeg, Rebecca Wilson, Deborah M Muoio

Cell Rep· August 2022

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Proteomics and phosphoproteomics datasets of a muscle-specific STIM1 loss-of-function mouse model.
Scott P Lyons, Rebecca J Wilson, Deborah M Muoio, Paul A Grimsrud

Data Brief· June 2022

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Mitochondrial lysine acylation and cardiometabolic stress: Truth or consequence?
Deborah M Muoio, Ashley S Williams, Paul A Grimsrud

Curr Opin Physiol· June 2022

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Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness.
Brian J Andonian, Alec Koss, Timothy R Koves, Elizabeth R Hauser, Monica J Hubal, Deborah M Muoio

Sci Rep· May 2022

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Disruption of STIM1-mediated Ca sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.
Rebecca J Wilson, Scott P Lyons, Timothy R Koves, Victoria G Bryson, Hengtao Zhang, Deborah M Muoio

Mol Metab· March 2022

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Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome.
Ashley S Williams, Timothy R Koves, Yasminye D Pettway, James A Draper, Dorothy H Slentz, Deborah M Muoio

iScience· January 2022

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Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle.
Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P Kerr, Deborah M Muoio

JCI Insight· September 2021

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Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Kari T Chambers, Michael A Cooper, Alison R Swearingen, Rita T Brookheart, George G Schweitzer, Deborah M Muoio

JCI Insight· May 2021

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Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
Kyle S McCommis, Attila Kovacs, Carla J Weinheimer, Trevor M Shew, Timothy R Koves, Deborah M Muoio

Nat Metab· November 2020

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Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.
Phillip J White, Amanda L Lapworth, Robert W McGarrah, Lydia Coulter Kwee, Scott B Crown, Deborah M Muoio

Cell Rep· November 2020

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