Publications by authors named "Deborah Packham"

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Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing.
Rebecca C Poulos, Dilmi Perera, Deborah Packham, Anushi Shah, Caroline Janitz

JNCI Cancer Spectr· June 2019

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Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells.
Qing Liu, Julie A I Thoms, Andrea C Nunez, Yizhou Huang, Kathy Knezevic, Deborah Packham

Clin Cancer Res· September 2018

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Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors.
Luke B Hesson, Benedict Ng, Peter Zarzour, Sameer Srivastava, Chau-To Kwok, Deborah Packham

Mol Cancer Res· December 2016

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Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients.
Qing Liu, Luke B Hesson, Andrea C Nunez, Deborah Packham, Nicholas J Hawkins

Cancer Genet· November 2016

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Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.
Julie A I Thoms, Kathy Knezevic, Jia Jenny Liu, Elias N Glaros, Thuan Thai, Deborah Packham

Mol Cell Biol· April 2016

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A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome.
Qing Liu, Luke B Hesson, Andrea C Nunez, Deborah Packham, Rachel Williams

Carcinogenesis· January 2016

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Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer.
Mathew A Sloane, Andrea C Nunez, Deborah Packham, Chau-To Kwok, Graeme Suthers

JAMA Oncol· October 2015

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Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.
Luke B Hesson, Deborah Packham, Chau-To Kwok, Andrea C Nunez, Benedict Ng

Hum Mutat· June 2015

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A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines.
Luke B Hesson, Deborah Packham, Emily Pontzer, Pauline Funchain, Charis Eng

Biol Proced Online· April 2012

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De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one.
Ajay Goel, Thuy-Phuong Nguyen, Hon-Chiu E Leung, Takeshi Nagasaka, Jennifer Rhees, Deborah Packham

Int J Cancer· February 2011

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Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.
Deborah Packham, Robyn L Ward, Vita Ap Lin, Nicholas J Hawkins, Megan P Hitchins

Diagn Mol Pathol· June 2009

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Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.
Megan P Hitchins, Vita Ap Lin, Andrew Buckle, Kayfong Cheong, Nimita Halani, Deborah Packham

Cancer Res· October 2007

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Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified.
Robyn Lynne Ward, Jenny Turner, Rachel Williams, Brita Pekarsky, Deborah Packham

J Pathol· December 2005

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MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.
Megan Hitchins, Rachel Williams, Kayfong Cheong, Nimita Halani, Vita A P Lin, Deborah Packham

Gastroenterology· November 2005

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