Publications by authors named "Deborah Schaefer"

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Calf Clinical Model of Cryptosporidiosis for Efficacy Evaluation of Therapeutics.
Michael W Riggs, Deborah A Schaefer

Methods Mol Biol· October 2025

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Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1.
Ryan Choi, Matthew A Hulverson, Deborah A Schaefer, Dana P Betzer, Michael W Riggs

PLoS Negl Trop Dis· July 2025

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Prodrug nanotherapy demonstrates anticryptosporidial efficacy in a mouse model of chronic infection.
Amalendu P Ranjan, Daniel J Czyzyk, Griselle Martinez-Traverso, Aygul Sadiqova, Margarita Valhondo, Deborah A Schaefer

RSC Pharm· December 2024

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Immunofluorescence detection of Ecytonucleospora hepatopenaei (EHP) in Penaeus vannamei.
Sungman Cho, Deborah A Schaefer, Hung N Mai, Michael W Riggs, Arun K Dhar

J Microbiol Methods· November 2024

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Genomic and virulence analysis of in vitro cultured Cryptosporidium parvum.
Nigel Yarlett, Mary Morada, Deborah A Schaefer, Kevin Ackman, Elizabeth Carranza

PLoS Pathog· February 2024

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Comparison of Toxicities among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis.
Matthew A Hulverson, Ryan Choi, Deborah A Schaefer, Dana P Betzer, Molly C McCloskey

Antimicrob Agents Chemother· April 2023

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Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis.
Cindy X Zhang, Melissa S Love, Case W McNamara, Victor Chi, Ashley K Woods, Deborah A Schaefer

Antimicrob Agents Chemother· January 2022

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One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.
Wesley C Van Voorhis, Matthew A Hulverson, Ryan Choi, Wenlin Huang, Samuel L M Arnold, Deborah A Schaefer

Vet Parasitol· January 2021

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Neonatal Mouse Gut Metabolites Influence Cryptosporidium parvum Infection in Intestinal Epithelial Cells.
Kelli L VanDussen, Lisa J Funkhouser-Jones, Marianna E Akey, Deborah A Schaefer, Kevin Ackman

mBio· December 2020

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Calf Clinical Model of Cryptosporidiosis for Efficacy Evaluation of Therapeutics.
Michael W Riggs, Deborah A Schaefer

Methods Mol Biol· November 2020

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Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned.
Ryan Choi, Matthew A Hulverson, Wenlin Huang, Rama S R Vidadala, Grant R Whitman, Deborah A Schaefer

Int J Parasitol· May 2020

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A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity.
Roberta M O'Connor, Felix J Nepveux V, Jaypee Abenoja, Gregory Bowden, Patricia Reis, Deborah A Schaefer

PLoS Pathog· May 2020

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Modelling Cryptosporidium infection in human small intestinal and lung organoids.
Inha Heo, Devanjali Dutta, Deborah A Schaefer, Nino Iakobachvili, Benedetta Artegiani

Nat Microbiol· July 2018

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A tick-acquired red meat allergy.
Joe Kevin Khoury, Neil Christian Khoury, Deborah Schaefer, Anup Chitnis, Getaw Worku Hassen

Am J Emerg Med· February 2018

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Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.
Matthew A Hulverson, Ryan Choi, Samuel L M Arnold, Deborah A Schaefer, Andrew Hemphill

Int J Parasitol· October 2017

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5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvum.
Wenlin Huang, Ryan Choi, Matthew A Hulverson, Zhongsheng Zhang, Molly C McCloskey, Deborah A Schaefer

Antimicrob Agents Chemother· August 2017

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Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection.
Samuel L M Arnold, Ryan Choi, Matthew A Hulverson, Deborah A Schaefer, Sumiti Vinayak

J Infect Dis· July 2017

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Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
Matthew A Hulverson, Sumiti Vinayak, Ryan Choi, Deborah A Schaefer, Alejandro Castellanos-Gonzalez

J Infect Dis· April 2017

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Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis.
Deborah A Schaefer, Dana P Betzer, Kylie D Smith, Zachary G Millman, Hannah C Michalski

J Infect Dis· December 2016

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Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.
Karine Thivierge, Sophie Cotton, Deborah A Schaefer, Michael W Riggs, Joyce To

PLoS Negl Trop Dis· February 2014

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Antibody fusions reduce onset of experimental Cryptosporidium parvum infection in calves.
Michael Imboden, Deborah A Schaefer, Robert D Bremel, E Jane Homan, Michael W Riggs

Vet Parasitol· August 2012

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Phospholipases and cationic peptides inhibit Cryptosporidium parvum sporozoite infectivity by parasiticidal and non-parasiticidal mechanisms.
Stéphane Carryn, Deborah A Schaefer, Michael Imboden, E Jane Homan, Robert D Bremel

J Parasitol· February 2012

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Antibodies fused to innate immune molecules reduce initiation of Cryptosporidium parvum infection in mice.
Michael Imboden, Michael W Riggs, Deborah A Schaefer, E Jane Homan, Robert D Bremel

Antimicrob Agents Chemother· April 2010

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Antigenic differences within the Cryptosporidium hominis and Cryptosporidium parvum surface proteins P23 and GP900 defined by monoclonal antibody reactivity.
Gregory D Sturbaum, Deborah A Schaefer, B Helen Jost, Charles R Sterling, Michael W Riggs

Mol Biochem Parasitol· June 2008

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Association of IL-10 expression by mucosal lymphocytes with increased expression of Cryptosporidium parvum epitopes in infected epithelium.
Carol R Wyatt, Wendy J Barrett, E Joan Brackett, Deborah A Schaefer, Michael W Riggs

J Parasitol· April 2002

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