Publications by authors named "Deborah Schechtman"

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PLCγ has a dual role in capsaicin-triggered neurogenic inflammation promoting mechanical hypersensitivity and edema in male mice.
Alexandre M do Nascimento, Ana M Rodrigues, Heloisa E G Ramos, Beatriz C de Moraes, Raphael S Santos, Deborah Schechtman

Am J Physiol Cell Physiol· September 2025

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Cerebral Dopamine Neurotrophic Factor (CDNF) Acts as a Trophic Factor Promoting Neuritogenesis in the Dorsal Root Ganglia (DRG) Neurons Through Activation of the PI3K Signaling Pathway.
Raphael de Siqueira Santos, Flávia Natale Borba, Dahienne Ferreira de Oliveira, Marcelo Felippe Santiago, Alexandre Martins do Nascimento, Deborah Schechtman

J Neurochem· August 2025

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Exploring protein-protein interactions for the development of new analgesics.
Alexandre Martins do Nascimento, Rauni Borges Marques, Allan Pradelli Roldão, Ana Maria Rodrigues, Rodrigo Mendes Eslava, Deborah Schechtman

Sci Signal· October 2024

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Identification of a novel alternative splicing isoform of the Hippo kinase STK3/MST2 with impaired kinase and cell growth suppressing activities.
Ana Maria Rodrigues, Ana Paula Zen Petisco Fiore, Gabriela D A Guardia, Rebeka Tomasin, André Azevedo Reis Teixeira, Deborah Schechtman

Oncogene· September 2024

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DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain-specific PKMζ.
Dimitrius Tansini Pramio, Felipe Monteleone Vieceli, Elisa Varella-Branco, Carolina Purcell Goes, Gerson Shigeru Kobayashi, Deborah Schechtman

Biochim Biophys Acta Gene Regul Mech· March 2023

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Odorant receptors as potential drug targets.
Rafaella G Naressi, Deborah Schechtman, Bettina Malnic

Trends Pharmacol Sci· January 2023

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Immunodominant antibody responses directed to SARS-CoV-2 hotspot mutation sites and risk of immune escape.
Jamille Ramos Oliveira, Cesar Manuel Remuzgo Ruiz, Rafael Rahal Guaragna Machado, Jhosiene Yukari Magawa, Isabela Pazotti Daher, Deborah Schechtman

Front Immunol· January 2023

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Chromatin Immunoprecipitation on Fixed Tissues and Cell Lines.
Dimitrius Pramio, Deborah Schechtman

Methods Mol Biol· November 2022

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Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target.
Beatriz C Moraes, Helder V Ribeiro-Filho, Allan P Roldão, Elaine F Toniolo, Gustavo P B Carretero, Deborah Schechtman

Sci Signal· April 2022

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The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling.
Lilian Cristina Russo, Rebeka Tomasin, Isaac Araújo Matos, Antonio Carlos Manucci, Sven T Sowa, Deborah Schechtman

J Biol Chem· September 2021

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Editorial: The Tribute of Physiology for the Understanding of COVID-19 Disease.
Georges Lefthériotis, Susan Wray, Adriana Castello Costa Girardi, Emmanuelle Vidal-Petiot, Matthew A Bailey, Deborah Schechtman

Front Physiol· September 2021

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Viral infection and smell loss: The case of COVID-19.
Isaias Glezer, Alexandre Bruni-Cardoso, Deborah Schechtman, Bettina Malnic

J Neurochem· May 2021

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Olfactory Dysfunction in Frontline Health Care Professionals During COVID-19 Pandemic in Brazil.
Mariana Ferreira Sbrana, Marco Aurélio Fornazieri, Alexandre Bruni-Cardoso, Vivian I Avelino-Silva, Deborah Schechtman

Front Physiol· March 2021

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High-throughput screening and validation of antibodies against synaptic proteins to explore opioid signaling dynamics.
Mariana Lemos Duarte, Nikita A Trimbake, Achla Gupta, Christine Tumanut, Xiaomin Fan, Deborah Schechtman

Commun Biol· February 2021

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Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4).
Marcelo Coutinho de Miranda, Michele Angela Rodrigues, Ana Carolina de Angelis Campos, Jerusa Araújo Quintão Arantes Faria, Marianna Kunrath-Lima, Deborah Schechtman

J Biol Chem· November 2019

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Exploring Morphine-Triggered PKC-Targets and Their Interaction with Signaling Pathways Leading to Pain via TrkA.
Darlene A Pena, Mariana Lemos Duarte, Dimitrius T Pramio, Lakshmi A Devi, Deborah Schechtman

Proteomes· October 2018

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Generating Conformation-Specific Polyclonal and Monoclonal Anti-Protein Kinase C Antibodies and Anti-Active State Specific PKC Antibodies.
Darlene A Pena, Denise M V Pacheco, Paulo S L Oliveira, Maria J M Alves, Deborah Schechtman

Curr Protoc Chem Biol· June 2018

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FBXO25 regulates MAPK signaling pathway through inhibition of ERK1/2 phosphorylation.
Felipe R Teixeira, Adriana O Manfiolli, Nichelle A Vieira, Ana Carla Medeiros, Priscila de O Coelho, Deborah Schechtman

Arch Biochem Biophys· May 2017

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Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors.
Nir Qvit, Deborah Schechtman, Darlene Aparecida Pena, Denise Aparecida Berti, Chrislaine Oliveira Soares

Int J Parasitol Drugs Drug Resist· April 2016

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Revisiting protein kinase-substrate interactions: Toward therapeutic development.
Paulo Sérgio L de Oliveira, Felipe Augusto N Ferraz, Darlene A Pena, Dimitrius T Pramio, Felipe A Morais, Deborah Schechtman

Sci Signal· March 2016

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Rational design and validation of an anti-protein kinase C active-state specific antibody based on conformational changes.
Darlene Aparecida Pena, Victor Piana de Andrade, Gabriela Ávila Fernandes Silva, José Ivanildo Neves, Paulo Sergio Lopes de Oliveira, Deborah Schechtman

Sci Rep· February 2016

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Protein folding creates structure-based, noncontiguous consensus phosphorylation motifs recognized by kinases.
Mariana Lemos Duarte, Darlene Aparecida Pena, Felipe Augusto Nunes Ferraz, Denise Aparecida Berti, Tiago José Paschoal Sobreira, Deborah Schechtman

Sci Signal· November 2014

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Activation of protein kinase C delta by ψδRACK peptide promotes embryonic stem cell proliferation through ERK 1/2.
Nicole Milaré Garavello, Darlene Aparecida Pena, José Matheus Camargo Bonatto, Mariana Lemos Duarte, Helio Miranda Costa-Junior, Deborah Schechtman

J Proteomics· December 2013

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Identification of εPKC targets during cardiac ischemic injury.
Grant Budas, Helio Miranda Costa, Julio Cesar Batista Ferreira, André Teixeira da Silva Ferreira, Jonas Perales, Deborah Schechtman

Circ J· October 2012

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FERM domain interaction with myosin negatively regulates FAK in cardiomyocyte hypertrophy.
Aline M Santos, Deborah Schechtman, Alisson C Cardoso, Carolina F M Z Clemente, Júlio C Silva

Nat Chem Biol· November 2011

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