Publications by authors named "Deborah Steplock"

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Retraction. Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.
Edward J. Weinman, Rajat S. Biswas, Quihong Peng, Lily Shen, Christina L. Turner, Deborah Steplock

J Clin Invest· June 2013

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Fibroblast growth factor-23-mediated inhibition of renal phosphate transport in mice requires sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) and synergizes with parathyroid hormone.
Edward J Weinman, Deborah Steplock, Shirish Shenolikar, Rajatsubhra Biswas

J Biol Chem· October 2011

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Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
Edward J Weinman, Rajatsubhra Biswas, Deborah Steplock, Peili Wang, Yuen-Sum Lau

Am J Physiol Renal Physiol· May 2011

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Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells.
Edward J Weinman, Deborah Steplock, Shirish Shenolikar, Thomas A Blanpied

Am J Physiol Renal Physiol· January 2011

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Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.
Edward J Weinman, Deborah Steplock, Yinghua Zhang, Rajatsubhra Biswas, Robert J Bloch

J Biol Chem· August 2010

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Role of NHERF and scaffolding proteins in proximal tubule transport.
Rochelle Cunningham, Rajatsubhra Biswas, Deborah Steplock, Shirish Shenolikar, Edward Weinman

Urol Res· August 2010

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Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney.
Edward J Weinman, Rajatsubhra Biswas, Deborah Steplock, Tia S Douglass, Rochelle Cunningham

J Biol Chem· April 2010

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PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP.
Edward J Weinman, Deborah Steplock, Boyoung Cha, Olga Kovbasnjuk, Nicholas A Frost

Am J Physiol Renal Physiol· December 2009

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Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells.
Rochelle Cunningham, Rajatsubhra Biswas, Marc Brazie, Deborah Steplock, Shirish Shenolikar

Am J Physiol Renal Physiol· February 2009

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The ROMK potassium channel is present in mammalian urinary tract epithelia and muscle.
David A Spector, Qing Yang, Leonid Klopouh, Jie Deng, Edward J Weinman, Deborah A Steplock

Am J Physiol Renal Physiol· December 2008

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Novel regulatory function for NHERF-1 in Npt2a transcription.
Syed Jalal Khundmiri, Aamir Ahmad, Ryan Everett Bennett, Edward J Weinman, Deborah Steplock

Am J Physiol Renal Physiol· April 2008

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Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets.
James W Voltz, Matthew Brush, Suzanne Sikes, Deborah Steplock, Edward J Weinman

J Biol Chem· November 2007

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Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1.
Edward J Weinman, Rajat S Biswas, Guihong Peng, Lily Shen, Christina L Turner, Deborah Steplock

J Clin Invest· November 2007

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Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.
Rakhilya Murtazina, Olga Kovbasnjuk, Nicholas C Zachos, Xuhang Li, Yueping Chen, Deborah Steplock

J Biol Chem· August 2007

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Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.
Rochelle Cunningham, Marc Brazie, Srilatha Kanumuru, Xiaofei E, Rajat Biswas, Deborah Steplock

J Am Soc Nephrol· May 2007

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Adenoviral expression of NHERF-1 in NHERF-1 null mouse renal proximal tubule cells restores Npt2a regulation by low phosphate media and parathyroid hormone.
Rochelle Cunningham, Deborah Steplock, Xiaofei E, Rajat S Biswas, Fengying Wang

Am J Physiol Renal Physiol· October 2006

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Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice.
Edward J Weinman, Viresh Mohanlal, Nicholas Stoycheff, Fengying Wang, Deborah Steplock

Am J Physiol Renal Physiol· April 2006

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Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media.
Rochelle Cunningham, Xiaofei E, Deborah Steplock, Shirish Shenolikar, Edward J Weinman

Am J Physiol Renal Physiol· October 2005

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Parathyroid hormone regulation of NA+,K+-ATPase requires the PDZ 1 domain of sodium hydrogen exchanger regulatory factor-1 in opossum kidney cells.
Syed Jalal Khundmiri, Edward J Weinman, Deborah Steplock, Judith Cole, Aamir Ahmad

J Am Soc Nephrol· September 2005

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Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells.
Rochelle Cunningham, Deborah Steplock, Fengying Wang, Huijun Huang, Xiaofei E

J Biol Chem· September 2004

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kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.
Peng Huang, Deborah Steplock, Edward J Weinman, Randy A Hall, Zhe Ding

J Biol Chem· June 2004

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Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
James B Wade, Jie Liu, Richard A Coleman, Rochelle Cunningham, Deborah A Steplock

Am J Physiol Cell Physiol· December 2003

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NHERF-1 is required for renal adaptation to a low-phosphate diet.
Edward J Weinman, Anuradha Boddeti, Rochelle Cunningham, Michael Akom, Fengying Wang, Deborah Steplock

Am J Physiol Renal Physiol· December 2003

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A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange.
Edward J Weinman, Yu Wang, Fengying Wang, Charmaine Greer, Deborah Steplock

Biochemistry· November 2003

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NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes.
Edward J Weinman, Deborah Steplock, Shirish Shenolikar

FEBS Lett· February 2003

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