Publications by authors named "Debra Chao"

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VISTA is an activating receptor in human monocytes.
Bryan M Rogers, Laura Smith, Zoltan Dezso, Xu Shi, Enrico DiGiammarino, Debra T Chao

J Exp Med· August 2021

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Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors.
Jason J Luke, Fabrice Barlesi, Ki Chung, Anthony W Tolcher, Karen Kelly, Debra T Chao

J Immunother Cancer· February 2021

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Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity.
Sun K Ho, Zhenghai Xu, Archana Thakur, Melvin Fox, Siu Sze Tan, Debra T Chao

Mol Cancer Ther· April 2020

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A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity.
Shiming Ye, Diane Cohen, Nicole A Belmar, Donghee Choi, Siu Sze Tan, Debra T Chao

Cancer Immunol Res· November 2019

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Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells.
Shiming Ye, Melvin I Fox, Nicole A Belmar, Mien Sho, Debra T Chao

J Immunol Res· July 2018

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LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.
James W Purcell, Sonia G Tanlimco, Jonathan Hickson, Melvin Fox, Mien Sho, Debra T Chao

Cancer Res· July 2018

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Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-α pathways.
Balaji Balasa, Rui Yun, Nicole A Belmar, Melvin Fox, Debra T Chao

Cancer Immunol Immunother· January 2015

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PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis.
Jacky Woo, Michel P M Vierboom, Hakju Kwon, Debra Chao, Shiming Ye

Arthritis Res Ther· November 2014

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Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR.
James W Purcell, Han K Kim, Sonia G Tanlimco, Minhtam Doan, Melvin Fox, Debra T Chao

Front Immunol· January 2014

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Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb.
Debra T Chao, Mian Su, Sonia Tanlimco, Mien Sho, Donghee Choi

J Cancer Res Clin Oncol· February 2013

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Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms.
Patricia A Culp, Donghee Choi, Yongke Zhang, Johnny Yin, Pui Seto, Debra T Chao

Clin Cancer Res· January 2010

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Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Frits van Rhee, Susann M Szmania, Myles Dillon, Anne M van Abbema, Xin Li, Debra Chao

Mol Cancer Ther· September 2009

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Dissociation of efficacy and cytokine release mediated by an Fc-modified anti-CD3 mAb in a chronic experimental autoimmune encephalomyelitis model.
Nicole A Belmar, John R Lombardo, Debra T Chao, Olga Li, Xiaohong Ma

J Neuroimmunol· July 2009

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Functional characterization of N297A, a murine surrogate for low-Fc binding anti-human CD3 antibodies.
Debra T Chao, Xiaohong Ma, Olga Li, Hyunjoo Park, Debbie Law

Immunol Invest· February 2009

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A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo.
Vinay Bhaskar, Dong Zhang, Melvin Fox, Pui Seto, Melanie H L Wong, Debra T Chao

J Transl Med· November 2007

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