Publications by authors named "Debra Ferguson"

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Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor.
Yiyun Yu, Miyeon Jang, Julie Miyashiro, Richard F Clark, Gui-Dong Zhu, Debra C Ferguson

J Med Chem· October 2024

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Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with Target Engagement.
Robin R Frey, Navendu Jana, Jacob V Gorman, Jin Wang, Heath A Smith, Debra C Ferguson

J Med Chem· October 2024

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Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Lu Zhang, Tianyu Cai, Xiaoyu Lin, Xiaoli Huang, Mai H Bui, Debra C Ferguson

Mol Cancer Ther· October 2021

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Corrigendum to "Investigation of biaryl heterocycles as inhibitors of Wee1 kinase" [Bioorg. Med. Chem. Lett. 29 (2019) 1481-1486].
Anthony Mastracchio, Chunqiu Lai, Maricel Torrent, Kenneth Bromberg, Fritz G Buchanan, Debra Ferguson

Bioorg Med Chem Lett· February 2020

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Effects of Buprenorphine in a Preclinical Orthotopic Tumor Model of Ovarian Carcinoma in Female CB17 SCID Mice.
Natalie A Bratcher, David J Frost, Jonathan Hickson, Xin Huang, Letty M Medina, Debra C Ferguson

J Am Assoc Lab Anim Sci· September 2019

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Investigation of biaryl heterocycles as inhibitors of Wee1 kinase.
Anthony Mastracchio, Chunqiu Lai, Maricel Torrent, Kenneth Bromberg, Fritz G Buchanan, Debra Ferguson

Bioorg Med Chem Lett· June 2019

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Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Loren M Lasko, Clarissa G Jakob, Rohinton P Edalji, Wei Qiu, Debra Montgomery, Debra Ferguson

Nature· June 2018

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Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Loren M Lasko, Clarissa G Jakob, Rohinton P Edalji, Wei Qiu, Debra Montgomery, Debra Ferguson

Nature· October 2017

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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.
William N Pappano, Jun Guo, Yupeng He, Debra Ferguson, Sujatha Jagadeeswaran

PLoS One· April 2016

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Therapeutic Molecular Phenotype of β-Blocker-Associated Reverse-Remodeling in Nonischemic Dilated Cardiomyopathy.
David P Kao, Brian D Lowes, Edward M Gilbert, Wayne Minobe, L Elaine Epperson, Debra A Ferguson

Circ Cardiovasc Genet· April 2015

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Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.
Yunsong Tong, Maricel Torrent, Alan S Florjancic, Kenneth D Bromberg, Fritz G Buchanan, Debra C Ferguson

ACS Med Chem Lett· January 2015

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SCN5A mutations associate with arrhythmic dilated cardiomyopathy and commonly localize to the voltage-sensing mechanism.
William P McNair, Gianfranco Sinagra, Matthew R G Taylor, Andrea Di Lenarda, Debra A Ferguson

J Am Coll Cardiol· May 2011

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An alternative salvage regimen for Helicobacter pylori-resistant patients with heart failure.
Robert Lee Page, Debra Ferguson, Mona Cantu

Cardiology· June 2008

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Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft models.
Alex R Shoemaker, Michael J Mitten, Jessica Adickes, Scott Ackler, Marion Refici, Debra Ferguson

Clin Cancer Res· June 2008

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ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models.
Cherrie K Donawho, Yan Luo, Yanping Luo, Thomas D Penning, Joy L Bauch, Debra C Ferguson

Clin Cancer Res· May 2007

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Prevalence of desmin mutations in dilated cardiomyopathy.
Matthew R G Taylor, Dobromir Slavov, Lisa Ku, Andrea Di Lenarda, Gianfranco Sinagra, Debra Ferguson

Circulation· March 2007

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Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy.
Matthew R G Taylor, Dobromir Slavov, Andreas Gajewski, Sylvia Vlcek, Lisa Ku, Debra A Ferguson

Hum Mutat· December 2005

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A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies.
Wen-Zhen Gu, Ingrid Joseph, Yi-Chun Wang, David Frost, Gerard M Sullivan, Debra Ferguson

Anticancer Drugs· November 2005

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Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy.
Elisa Carniel, Matthew R G Taylor, Gianfranco Sinagra, Andrea Di Lenarda, Lisa Ku, Debra A Ferguson

Circulation· July 2005

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Antitumor activity of orally bioavailable farnesyltransferase inhibitor, ABT-100, is mediated by antiproliferative, proapoptotic, and antiangiogenic effects in xenograft models.
Debra Ferguson, Luis E Rodriguez, Joann P Palma, Marion Refici, Kenneth Jarvis

Clin Cancer Res· April 2005

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Natural history of dilated cardiomyopathy due to lamin A/C gene mutations.
Matthew R G Taylor, Pamela R Fain, Gianfranco Sinagra, Misi L Robinson, Alastair D Robertson, Debra A Ferguson

J Am Coll Cardiol· March 2003

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Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents.
Brian D Lowes, Edward M Gilbert, William T Abraham, Wayne A Minobe, Patti Larrabee, Debra Ferguson

N Engl J Med· May 2002

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Intergroup Attitudes among Ethnic Minority Adolescents: A Causal Model.
Jean S Phinney, Debra L Ferguson, Jerry D Tate

Child Dev· October 1997

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