Publications by authors named "Deepa Pookot"

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Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity.
Sayumi Yamazoe, Yam Poudel, Emanuela Sega, Anandaroop Mukhopadhyay, Radha Ramakrishnan, Deepa Pookot

J Med Chem· June 2025

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Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.
Jeffrey J Jackson, Grant M Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Deepa Pookot

J Med Chem· October 2022

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Editor's Note: Epigenetic Modifications of Gene through Chromatin Remodeling in Prostate Cancer.
Ken Kawamoto, Steven T Okino, Robert F Place, Shinji Urakami, Hiroshi Hirata, Deepa Pookot

Clin Cancer Res· May 2021

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Tumors establish resistance to immunotherapy by regulating T recruitment via CCR4.
Lisa A Marshall, Sachie Marubayashi, Aparna Jorapur, Scott Jacobson, Mikhail Zibinsky, Deepa Pookot

J Immunother Cancer· November 2020

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Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity and .
Yamini M Ohol, Michael T Sun, Gene Cutler, Paul R Leger, Dennis X Hu, Deepa Pookot

Mol Cancer Ther· October 2020

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Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
Paul R Leger, Dennis X Hu, Berenger Biannic, Minna Bui, Xinping Han, Deepa Pookot

J Med Chem· May 2020

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Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T Trafficking into the Tumor Microenvironment.
Jeffrey J Jackson, John M Ketcham, Ashkaan Younai, Betty Abraham, Berenger Biannic, Deepa Pookot

J Med Chem· July 2019

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miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells.
Emily J Noonan, Robert F Place, Shashwati Basak, Deepa Pookot, Long-Cheng Li

Oncotarget· September 2010

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Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma.
Jared M Whitson, Emily J Noonan, Deepa Pookot, Robert F Place, Rajvir Dahiya

Int J Cancer· July 2009

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Toxic and chemopreventive ligands preferentially activate distinct aryl hydrocarbon receptor pathways: implications for cancer prevention.
Steven T Okino, Deepa Pookot, Shashwati Basak, Rajvir Dahiya

Cancer Prev Res (Phila)· March 2009

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Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function.
Shashwati Basak, Deepa Pookot, Emily J Noonan, Rajvir Dahiya

Mol Cancer Ther· October 2008

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Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification.
Shahana Majid, Nobuyuki Kikuno, Jason Nelles, Emily Noonan, Yuichiro Tanaka, Deepa Pookot

Cancer Res· April 2008

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Antitumor effect of dsRNA-induced p21(WAF1/CIP1) gene activation in human bladder cancer cells.
Zhong Chen, Robert F Place, Zhe-Jun Jia, Deepa Pookot, Rajvir Dahiya

Mol Cancer Ther· March 2008

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MicroRNA-373 induces expression of genes with complementary promoter sequences.
Robert F Place, Long-Cheng Li, Deepa Pookot, Emily J Noonan, Rajvir Dahiya

Proc Natl Acad Sci U S A· February 2008

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A dioxin-responsive enhancer 3' of the human CYP1A2 gene.
Steven T Okino, Linda C Quattrochi, Deepa Pookot, Mieko Iwahashi, Rajvir Dahiya

Mol Pharmacol· December 2007

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Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer.
Steven T Okino, Deepa Pookot, Shahana Majid, Hong Zhao, Long-Cheng Li

Mol Carcinog· October 2007

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Epigenetic modifications of RASSF1A gene through chromatin remodeling in prostate cancer.
Ken Kawamoto, Steven T Okino, Robert F Place, Shinji Urakami, Hiroshi Hirata, Deepa Pookot

Clin Cancer Res· May 2007

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Small dsRNAs induce transcriptional activation in human cells.
Long-Cheng Li, Steven T Okino, Hong Zhao, Deepa Pookot, Robert F Place

Proc Natl Acad Sci U S A· November 2006

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The E-cadherin -160 C/A polymorphism and prostate cancer risk in white and black American men.
Deepa Pookot, Long-Cheng Li, Z Laura Tabatabai, Yuichiro Tanaka, Kirsten L Greene

J Urol· August 2006

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Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer.
Steven T Okino, Deepa Pookot, Long-Cheng Li, Hong Zhao, Shinji Urakami

Cancer Res· August 2006

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Catechol-O-methyltransferase gene polymorphisms in benign prostatic hyperplasia and sporadic prostate cancer.
Yuichiro Tanaka, Masahiro Sasaki, Hiroaki Shiina, Takashi Tokizane, Masao Deguchi, Deepa Pookot

Cancer Epidemiol Biomarkers Prev· February 2006

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Ethnic group-related differences in CpG hypermethylation of the GSTP1 gene promoter among African-American, Caucasian and Asian patients with prostate cancer.
Hideki Enokida, Hiroaki Shiina, Shinji Urakami, Mikio Igawa, Tatsuya Ogishima, Deepa Pookot

Int J Cancer· August 2005

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The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma.
Hiroaki Shiina, Mikio Igawa, Julia Breault, Leopoldo Ribeiro-Filho, Deepa Pookot

Clin Cancer Res· June 2003

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