Publications by authors named "Deepika Balakrishna"

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Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1.
Mark Sabat, Daniel W Carney, Gloria Hernandez-Torres, Tony S Gibson, Deepika Balakrishna

J Med Chem· June 2024

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Correction to "Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 ()-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3-1,2,4-triazol-3-one, by Fragment-Based Drug Design".
Mark Sabat, Douglas R Dougan, Jacques Ermolieff, Petro Halkowycz, Beverly Knight, Deepika Balakrishna

J Med Chem· November 2021

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Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 ()-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3-1,2,4-triazol-3-one, by Fragment-Based Drug Design.
Mark Sabat, Douglas R Dougan, Beverly Knight, J David Lawson, Nicholas Scorah, Deepika Balakrishna

J Med Chem· September 2021

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Using Target Engagement Biomarkers to Predict Clinical Efficacy of MetAP2 Inhibitors.
Pamela J Farrell, Christopher J Zopf, Huey-Jing Huang, Deepika Balakrishna, Corine Holub

J Pharmacol Exp Ther· November 2019

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CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice.
Matthew Riopel, Melanie Vassallo, Erik Ehinger, Jennifer Pattison, Karen Bowden, Deepika Balakrishna

Mol Metab· February 2019

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Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.
Matthew Riopel, Jong Bae Seo, Gautam K Bandyopadhyay, Pingping Li, Joshua Wollam, Deepika Balakrishna

J Clin Invest· April 2018

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MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody.
Pamela J Farrell, Jennifer Matuszkiewicz, Deepika Balakrishna, Shweta Pandya, Mark S Hixon

Mol Cancer Ther· July 2017

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Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate.
Walter Keung, Amogh Boloor, Jason Brown, Andre Kiryanov, Anthony Gangloff, Deepika Balakrishna

Bioorg Med Chem Lett· February 2017

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Biological characterization of TAK-901, an investigational, novel, multitargeted Aurora B kinase inhibitor.
Pamela Farrell, Lihong Shi, Jennifer Matuszkiewicz, Deepika Balakrishna, Takashi Hoshino

Mol Cancer Ther· April 2013

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Target cell defense prevents the development of diabetes after viral infection.
Malin Flodström, Amy Maday, Deepika Balakrishna, Mary Malo Cleary, Akihiko Yoshimura

Nat Immunol· April 2002

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