Publications by authors named "Delin You"

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Biosynthesis of the benzylpyrrolidine precursor in anisomycin by a unique ThDP-dependent enzyme.
Yongjian Qiao, Junbo Wang, Dashan Zhang, Xiaoqing Zheng, Baixin Lin, Delin You

Synth Syst Biotechnol· August 2024

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O-methyltransferase CbzMT catalyzes iterative 3,4-dimethylations for carbazomycin biosynthesis.
Baixin Lin, Dashan Zhang, Junbo Wang, Yongjian Qiao, Jinjin Wang, Delin You

Eng Microbiol· June 2024

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Chemistry and biosynthesis of bacterial polycyclic xanthone natural products.
Lingxin Kong, Zixin Deng, Delin You

Nat Prod Rep· November 2022

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Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in var. Beijingensis.
Dashan Zhang, Junbo Wang, Yongjian Qiao, Baixin Lin, Zixin Deng, Delin You

Antibiotics (Basel)· October 2022

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Acyltransferase AniI, a Tailoring Enzyme with Broad Substrate Tolerance for High-Level Production of Anisomycin.
Qing Wang, Lingxin Kong, Xiaoqing Zheng, Jufang Shen, Junbo Wang, Delin You

Appl Environ Microbiol· June 2021

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Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications.
Sucheng Zhu, Tao Zheng, Lingxin Kong, Jinli Li, Bo Cao, Delin You

Biomolecules· October 2020

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Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in .
Weinan Yang, Lingxin Kong, Qing Wang, Zixin Deng, Delin You

Synth Syst Biotechnol· September 2020

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Flavin Adenine Dinucleotide-Dependent Halogenase XanH and Engineering of Multifunctional Fusion Halogenases.
Lingxin Kong, Qing Wang, Zixin Deng, Delin You

Appl Environ Microbiol· September 2020

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Three Recently Diverging Duplicated Methyltransferases Exhibit Substrate-Dependent Regioselectivity Essential for Xantholipin Biosynthesis.
Lingxin Kong, Qing Wang, Weinan Yang, Jufang Shen, Yan Li, Delin You

ACS Chem Biol· August 2020

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DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome.
Yihua Sun, Lingxin Kong, Guojun Wu, Bo Cao, Xiaoyan Pang, Delin You

Biomolecules· August 2020

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Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage.
Bo Cao, Xiaolin Wu, Jieliang Zhou, Hang Wu, Lili Liu, Delin You

Nucleic Acids Res· July 2020

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CtcS, a MarR family regulator, regulates chlortetracycline biosynthesis.
Lingxin Kong, Jia Liu, Xiaoqing Zheng, Zixin Deng, Delin You

BMC Microbiol· December 2019

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Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA.
Yi Chen, Tao Zheng, Jinli Li, Jinjie Cui, Zixin Deng, Delin You

Sci Rep· May 2019

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Quantitative mapping of DNA phosphorothioatome reveals phosphorothioate heterogeneity of low modification frequency.
Jinli Li, Yi Chen, Tao Zheng, Lingxin Kong, Sucheng Zhu, Delin You

PLoS Genet· April 2019

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Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in var. Hangzhouwanensis.
Yan Li, Lingxin Kong, Jufang Shen, Qing Wang, Qian Liu, Delin You

Synth Syst Biotechnol· March 2019

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A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in var. beijingensis.
Jufang Shen, Lingxin Kong, Yan Li, Xiaoqing Zheng, Qing Wang, Delin You

Synth Syst Biotechnol· March 2019

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Oxidation of phosphorothioate DNA modifications leads to lethal genomic instability.
Stefanie Kellner, Michael S DeMott, Ching Pin Cheng, Brandon S Russell, Bo Cao, Delin You

Nat Chem Biol· August 2017

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Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps.
Xiaoqing Zheng, Qiuxiang Cheng, Fen Yao, Xiaozheng Wang, Lingxin Kong, Delin You

Proc Natl Acad Sci U S A· April 2017

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[Function of Streptomyces antibiotic regulatory proteins family transcriptional regulator ctcB in the biosynthetic cluster of chlortetracycline].
Jia Liu, Tao Zhu, Pengfei Wang, Lingxin Kong, Songmei Wang, Delin You

Wei Sheng Wu Xue Bao· September 2016

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[Function of methyltransferase gene pieB2 in the biosynthetic cluster of piericidin A1].
Zhenyu Zhao, Qian Liu, Delin You

Wei Sheng Wu Xue Bao· July 2016

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A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation.
Lingxin Kong, Weike Zhang, Yit Heng Chooi, Lu Wang, Bo Cao, Delin You

Cell Chem Biol· April 2016

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[Genetic manipulation system and genomic library of Streptomyces luteosporeus NRRL 2401].
Xueqing Cheng, Tao Zhu, Zixin Deng, Delin You

Wei Sheng Wu Xue Bao· February 2016

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DndEi Exhibits Helicase Activity Essential for DNA Phosphorothioate Modification and ATPase Activity Strongly Stimulated by DNA Substrate with a GAAC/GTTC Motif.
Tao Zheng, Pan Jiang, Bo Cao, Qiuxiang Cheng, Lingxin Kong, Delin You

J Biol Chem· January 2016

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Regulation of DNA phosphorothioate modifications by the transcriptional regulator DptB in Salmonella.
Qiuxiang Cheng, Bo Cao, Fen Yao, Jinli Li, Zixin Deng, Delin You

Mol Microbiol· September 2015

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In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex.
Bo Cao, Xiaoqing Zheng, Qiuxiang Cheng, Fen Yao, Tao Zheng, Delin You

Sci Rep· July 2015

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