Publications by authors named "Demei Xu"

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UBQLN4 regulates seizures by promoting the proteasomal degradation of GluN2B.
Wang Jing, Yan Xia, Zhang Hui, Wang Xuefeng, Xu Demei

Neurobiol Dis· October 2025

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Inhibiting SNX14 Alleviates Epileptic Seizures by Regulating GluA2 Degradation via the Lysosomal Pathway.
Wang Jing, Cao Qingqing, Yan Xia, Qin Ningxiang, Xu Demei, Wang Xuefeng

Mol Neurobiol· August 2025

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D2HGDH Deficiency Regulates Seizures through GSH/Prdx6/ROS-Mediated Excitatory Synaptic Activity.
Zhijuan Zhang, Hui Zhang, Peng Zhang, Rong Li, Jinyu Zhou, Demei Xu

Adv Sci (Weinh)· April 2025

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ERRα regulates synaptic transmission through reactive oxygen species in hippocampal neurons.
De-Mei Xu, Zhi-Juan Zhang, Hao-Kun Guo, Guo-Jun Chen, Yuan-Lin Ma

Heliyon· January 2024

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GSDMD knockdown attenuates phagocytic activity of microglia and exacerbates seizure susceptibility in TLE mice.
Xiaoxia Yang, Qingqing Cao, Yi Guo, Jingchuan He, Demei Xu

J Neuroinflammation· August 2023

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KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Xu, Demei Xu, Xuefeng Wang

Cell Death Differ· July 2023

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GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
Aolei Lin, Yi Guo, Hui Zhang, Peijia Lin, Kaiyan Tao, Demei Xu

Biochim Biophys Acta Mol Basis Dis· June 2023

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Response to antiepileptic drugs after unsuccessful epilepsy surgery: A multivariate analysis of 103 patients.
Junhong Ma, Junhong Wu, Hongnian Chen, Yuanyuan Chen, Demei Xu, Xuefeng Wang

Seizure· October 2020

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Age- and Nicotine-Associated Gene Expression Changes in the Hippocampus of APP/PS1 Mice.
Jie Yang, Yan Long, De-Mei Xu, Bing-Lin Zhu, Xiao-Juan Deng

J Mol Neurosci· December 2019

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TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Haiqing Zhang, Xin Tian, Xi Lu, Demei Xu, Yi Guo, Xuefeng Wang

J Clin Invest· September 2019

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Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus.
Qin Yang, Zifeng Huang, Yangfu Luo, Fangshuo Zheng, Yida Hu, Demei Xu, Xuefeng Wang

EBioMedicine· September 2019

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Transgenic overexpression of furin increases epileptic susceptibility.
Yi Yang, Miaoqing He, Xin Tian, Yi Guo, Feng Liu, Demei Xu, Xuefeng Wang

Cell Death Dis· October 2018

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GPR40 modulates epileptic seizure and NMDA receptor function.
Yong Yang, Xin Tian, Demei Xu, Fangshuo Zheng, Xi Lu, Xin Xu, Xuefeng Wang

Sci Adv· October 2018

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Furin promotes dendritic morphogenesis and learning and memory in transgenic mice.
Binglin Zhu, Lige Zhao, Dong Luo, Demei Xu, Tao Tan

Cell Mol Life Sci· July 2018

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ZDHHC8 critically regulates seizure susceptibility in epilepsy.
Qin Yang, Fangshuo Zheng, Yida Hu, Yi Yang, Yun Li, Demei Xu, Xuefeng Wang

Cell Death Dis· July 2018

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Inhibition of Cgkii Suppresses Seizure Activity and Hippocampal Excitation by Regulating the Postsynaptic Delivery of Glua1.
Juan Gu, Xin Tian, Wei Wang, Qin Yang, Peijia Lin, Demei Xu, Xuefeng Wang

Cell Physiol Biochem· June 2018

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POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Xinshi Wang, Xin Tian, Yong Yang, Xi Lu, Yun Li, Demei Xu, Xin Xu, Xuefeng Wang

Expert Opin Ther Targets· December 2017

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Polychlorinated biphenyl quinone induces mitochondrial-mediated and caspase-dependent apoptosis in HepG2 cells.
Demei Xu, Lingrui Li, Lichao Liu, Hui Dong, Qin Deng

Environ Toxicol· September 2015

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Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Hui Dong, Qiong Shi, Xiufang Song, Juanli Fu, Lihua Hu, Demei Xu

Toxicol Appl Pharmacol· July 2015

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Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Lihua Hu, Chuanyang Su, Xiufang Song, Qiong Shi, Juanli Fu, Demei Xu

Neurotoxicology· July 2015

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Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Demei Xu, Chuanyang Su, Xiufang Song, Qiong Shi, Juanli Fu

Chem Res Toxicol· June 2015

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Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Chuanyang Su, Pu Zhang, Xiufang Song, Qiong Shi, Juanli Fu, Demei Xu

Chem Res Toxicol· April 2015

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Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xiaomin Xia, Chuanyang Su, Juanli Fu, Pu Zhang, Xiaoji Jiang, Demei Xu

Int Immunopharmacol· October 2014

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Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Demei Xu, Lihua Hu, Chuanyang Su, Xiaomin Xia, Pu Zhang, Duo Xu

Toxicol Appl Pharmacol· October 2014

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Tetrachlorobenzoquinone induces acute liver injury, up-regulates HO-1 and NQO1 expression in mice model: the protective role of chlorogenic acid.
Demei Xu, Lihua Hu, Xiaomin Xia, Jianbo Song, Lingrui Li

Environ Toxicol Pharmacol· May 2014

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