Publications by authors named "Demeng Chen"

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Neoadjuvant chemotherapy plus anlotinib in the treatment of resectable head and neck squamous cell carcinoma: A pilot phase II trial.
Qianting He, Shuojin Huang, Dongxiao Tang, Congyuan Cao, Wanhang Zhou, Jie Chen, Yanchen Li, Demeng Chen

Cancer Commun (Lond)· May 2025

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Author Correction: Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils.
Xiaochen Wang, Maosheng Cheng, Shuang Chen, Caihua Zhang, Rongsong Ling, Ke Chen, Demeng Chen

Nat Commun· May 2025

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Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils.
Xiaochen Wang, Maosheng Cheng, Shuang Chen, Caihua Zhang, Rongsong Ling, Ke Chen, Demeng Chen

Nat Commun· April 2025

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Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice.
Shuang Chen, Chensong Huang, Kang Li, Maosheng Cheng, Caihua Zhang, Xiaochen Wang, Demeng Chen

J Clin Invest· January 2025

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The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation.
Tailai Du, Yanchuang Han, Hui Han, Ting Xu, Youchen Yan, Chen Liu, Demeng Chen

Nat Cardiovasc Res· December 2024

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Di-(2-ethylhexyl) phthalate exposure induces premature testicular senescence by disrupting mitochondrial respiratory chain through STAT5B-mitoSTAT3 in Leydig cell.
Haiming Cao, Qigen Xie, Peng Luo, Jiaqi Chen, Kai Xia, Demeng Chen

Geroscience· October 2024

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Loss of NAT10 Reduces the Translation of mRNA Through ac4C Modification in Cardiomyocytes and Induces Heart Failure.
Ting Xu, Tailai Du, Xiaodong Zhuang, Xin He, Youchen Yan, Chen Liu, Demeng Chen

J Am Heart Assoc· October 2024

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Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism.
Qiwen Li, Shuang Jiang, Kexin Lei, Hui Han, Yaqian Chen, Chenchen Zhou, Demeng Chen

J Clin Invest· September 2024

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ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4 macrophage infiltration.
Caihua Zhang, Kang Li, Hongzhang Zhu, Maosheng Cheng, Shuang Chen, Cheng Wang, Demeng Chen

Nat Commun· August 2024

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Targeting BRD4 attenuates the stemness and aggressiveness of ameloblastoma.
Jiaxiang Xie, Jingqi Zhang, Gan Xiong, Shengqi Ouyang, Bokai Yun, Demeng Chen, Cheng Wang

Oral Dis· July 2024

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Metabolic reprogramming driven by METTL1-mediated tRNA m7G modification promotes acquired anlotinib resistance in oral squamous cell carcinoma.
Jie Chen, Qimin Zhou, Shuai Li, Rongsong Ling, Yiwei Zhao, Demeng Chen

Transl Res· June 2024

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CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs.
Gan Xiong, Zhi Chen, Qianwen Liu, Fang Peng, Caihua Zhang, Maosheng Cheng, Shuang Chen, Demeng Chen

J Immunother Cancer· May 2024

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SOX18 meditates the resistance of Bmi1-expressing cells to cetuximab in HNSCC.
Caihua Zhang, Zhi Chen, Nailin Gao, Gan Xiong, Peng Chen, Demeng Chen

Oral Dis· April 2024

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METTL3-mediated ALDH mA methylation regulates the malignant behavior of BMI1 HNSCC stem cells.
Zhi Chen, Jie Chen, Xiaohong Xu, Qiuli Li, Caihua Zhang, Demeng Chen

Oral Dis· April 2024

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CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer.
Maosheng Cheng, Shuang Chen, Kang Li, Ganping Wang, Gan Xiong, Zhi Chen, Xiaochen Wang, Demeng Chen

Nat Commun· April 2024

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Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification.
Kang Li, Caihua Zhang, Ruoxing Zhou, Maosheng Cheng, Rongsong Ling, Shuang Chen, Jie Chen, Demeng Chen

Int J Oral Sci· April 2024

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Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma.
Gan Xiong, Nan Xie, Min Nie, Rongsong Ling, Bokai Yun, Chen Yi, Demeng Chen, Cheng Wang

Int J Oral Sci· February 2024

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RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA acC modification.
Xiaochen Wang, Rongsong Ling, Yurong Peng, Weiqiong Qiu, Demeng Chen

Int J Oral Sci· January 2024

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The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma.
Kang Li, Jie Chen, Caihua Zhang, Maosheng Cheng, Shuang Chen, Zhi Chen, Xiaochen Wang, Qianming Chen, Demeng Chen

J Clin Invest· October 2023

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DAGLβ is the principal synthesizing enzyme of 2-AG and promotes aggressive phenotype of intrahepatic cholangiocarcinoma via AP-1/DAGLβ/miR4516 feedforward circuitry.
Mingjian Ma, Guangyan Zeng, Bingyan Tan, Guangyin Zhao, Qiao Su, Zicheng Wang, Jiancong Chen, Demeng Chen

Am J Physiol Gastrointest Liver Physiol· September 2023

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Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma.
Xiuyun Xu, Jiaxiang Xie, Rongsong Ling, Shengqi Ouyang, Gan Xiong, Demeng Chen, Cheng Wang

Int J Oral Sci· September 2023

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The translational landscape of human vascular smooth muscle cells identifies novel short open reading frame-encoded peptide regulators for phenotype alteration.
Kang Li, Bin Li, Dihua Zhang, Tailai Du, Huimin Zhou, Youchen Yan, Chen Liu, Demeng Chen

Cardiovasc Res· July 2023

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BET inhibition triggers antitumor immunity by enhancing MHC class I expression in head and neck squamous cell carcinoma.
Ming Zhang, Ganping Wang, Zhikun Ma, Gan Xiong, Wenjin Wang, Chen Yi, Demeng Chen, Cheng Wang

Mol Ther· November 2022

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SRF-derived miR210 and miR30c both repress beating cardiomyocyte formation in the differentiation system of embryoid body.
Guoxing Zheng, Zhuzhen He, Yingsi Lu, Qingqing Zhu, Yizhou Jiang, Demeng Chen, Chengming Zhu

Biochem Biophys Res Commun· October 2022

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FOSL1 promotes tumor growth and invasion in ameloblastoma.
Gan Xiong, Shengqi Ouyang, Nan Xie, Jiaxiang Xie, Wenjin Wang, Chen Yi, Demeng Chen, Cheng Wang

Front Oncol· September 2022

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