Publications by authors named "Demis Menolfi"

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Exploring patterns in molecular biology.
Demis Menolfi

Mol Cell· January 2025

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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.
Xiaohui Lin, Dipika Gupta, Alina Vaitsiankova, Seema Khattri Bhandari, Kay Sze Karina Leung, Demis Menolfi

Mol Cell· October 2024

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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.
Xiaohui Lin, Dipika Gupta, Alina Vaitsiankova, Seema Khattri Bhandari, Kay Sze Karina Leung, Demis Menolfi

bioRxiv· March 2024

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Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements.
Zhiming Li, Shoufu Duan, Xu Hua, Xiaowei Xu, Yinglu Li, Demis Menolfi

Nature· November 2023

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ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Demis Menolfi, Brian J Lee, Hanwen Zhang, Wenxia Jiang, Nicole E Bowen

Nat Commun· June 2023

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ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Demis Menolfi, Brian J Lee, Hanwen Zhang, Wenxia Jiang, Nicole E Bowen

bioRxiv· May 2023

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70 years of the DNA double helix: An interview with Daniela Rhodes.
Demis Menolfi, Daniela Rhodes

Mol Cell· April 2023

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DNA-PKcs kinase activity orchestrates both end-processing and end-ligation.
Demis Menolfi, Shan Zha

Trends Cell Biol· February 2022

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Targeting BRCA-mutated tumors in mitosis.
Demis Menolfi, Shan Zha

Nat Cancer· December 2021

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DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.
Xiaobin S Wang, Demis Menolfi, Foon Wu-Baer, Marco Fangazio, Stefanie N Meyer

Proc Natl Acad Sci U S A· September 2021

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Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.
Sumedha Agashe, Chinnu Rose Joseph, Teresa Anne Clarisse Reyes, Demis Menolfi, Michele Giannattasio

Nat Commun· April 2021

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FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis.
Maja Milanovic, Zhengping Shao, Verna M Estes, Xiaobin S Wang, Demis Menolfi

J Immunol· March 2021

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The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange.
Maja Milanovic, Lisa Sprinzen, Demis Menolfi, Ji-Hoon Lee, Kenta Yamamoto

Cancer Res· January 2021

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Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo.
Demis Menolfi, Dana Branzei

Methods Mol Biol· March 2020

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ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.
Demis Menolfi, Shan Zha

Cell Biosci· January 2020

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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.
Demis Menolfi, Wenxia Jiang, Brian J Lee, Tatiana Moiseeva, Zhengping Shao

Nat Commun· December 2018

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G2/M chromosome transactions essentially relying on Smc5/6.
Dana Branzei, Demis Menolfi

Cell Cycle· December 2016

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Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.
Demis Menolfi, Axel Delamarre, Armelle Lengronne, Philippe Pasero, Dana Branzei

Mol Cell· December 2015

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Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.
Lisa E Hang, Jie Peng, Wei Tan, Barnabas Szakal, Demis Menolfi

Mol Cell· October 2015

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Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.
Madhusoodanan Urulangodi, Marek Sebesta, Demis Menolfi, Barnabas Szakal, Julie Sollier

Genes Dev· October 2015

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DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.
Victor Gonzalez-Huici, Barnabas Szakal, Madhusoodanan Urulangodi, Ivan Psakhye, Federica Castellucci, Demis Menolfi

EMBO J· February 2014

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During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks.
Denise E Bustard, Demis Menolfi, Kristian Jeppsson, Lindsay G Ball, Sidney Carter Dewey

J Biol Chem· March 2012

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