Publications by authors named "Dena Leeman"

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CRISPR-Cas9 screens reveal regulators of ageing in neural stem cells.
Tyson J Ruetz, Angela N Pogson, Chloe M Kashiwagi, Stephanie D Gagnon, Bhek Morton, Dena S Leeman

Nature· October 2024

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FOXO3 regulates a common genomic program in aging and glioblastoma stem cells.
Amanda J Audesse, Galina Karashchuk, Zachary A Gardell, Nelli S Lakis, Sun Y Maybury-Lewis, Dena S Leeman

Aging Cancer· December 2021

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Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells.
Brenna S McCauley, Luyang Sun, Ruofan Yu, Minjung Lee, Haiying Liu, Dena S Leeman

Nat Aging· August 2021

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Single-cell analysis reveals T cell infiltration in old neurogenic niches.
Ben W Dulken, Matthew T Buckley, Paloma Navarro Negredo, Naresha Saligrama, Romain Cayrol, Dena S Leeman

Nature· July 2019

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Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging.
Dena S Leeman, Katja Hebestreit, Tyson Ruetz, Ashley E Webb, Andrew McKay

Science· March 2018

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Dynamic landscape and regulation of RNA editing in mammals.
Meng How Tan, Qin Li, Raghuvaran Shanmugam, Robert Piskol, Jennefer Kohler, Dena S Leeman

Nature· October 2017

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Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage.
Ben W Dulken, Dena S Leeman, Stéphane C Boutet, Katja Hebestreit, Anne Brunet

Cell Rep· January 2017

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Stem cells: Sex specificity in the blood.
Dena S Leeman, Anne Brunet

Nature· January 2014

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FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.
Ashley E Webb, Elizabeth A Pollina, Thomas Vierbuchen, Noelia Urbán, Duygu Ucar, Dena S Leeman

Cell Rep· August 2013

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Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.
Eric L Greer, Travis J Maures, Anna G Hauswirth, Erin M Green, Dena S Leeman

Nature· July 2010

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K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to gamma-secretase inhibitors.
Thomas Kindler, Melanie G Cornejo, Claudia Scholl, Jianing Liu, Dena S Leeman

Blood· October 2008

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Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
Kim De Keersmaecker, Jennifer L Rocnik, Rafael Bernad, Benjamin H Lee, Dena Leeman

Mol Cell· July 2008

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Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.
Gerlinde Wernig, Michael G Kharas, Rachel Okabe, Sandra A Moore, Dena S Leeman

Cancer Cell· April 2008

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