Publications by authors named "Denisa D Wagner"

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Neutrophil extracellular traps and peptidylarginine deiminase 4-mediated inflammasome activation link diabetes to cardiorenal injury and heart failure.
Nicolas Schommer, Nicolas Gendron, Krystin Krauel, Stijn Van Bruggen, Pierre-André Jarrot, Denisa D Wagner

Eur Heart J· November 2025

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A GPVI-platelet-neutrophil-NET axis drives systemic sclerosis.
Roxane Darbousset, Leetah Senkpeil, Julia Kuehn, Spoorthi Balu, Dhruv Miglani, Denisa D Wagner

bioRxiv· January 2025

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Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage.
Pierre-André Jarrot, Jiyoun Kim, William Chan, Lukas Heger, Nicolas Schommer, Denisa D Wagner

Front Immunol· December 2024

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Reflections on Targeting Neutrophil Extracellular Traps in Deep Vein Thrombosis.
Kimberly Martinod, Denisa D Wagner

Arterioscler Thromb Vasc Biol· August 2024

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Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium.
Lukas A Heger, Nicolas Schommer, Stijn Van Bruggen, Casey E Sheehy, William Chan, Denisa D Wagner

Sci Rep· June 2024

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Neutrophil peptidylarginine deiminase 4 plays a systemic role in obesity-induced chronic inflammation in mice.
Stijn Van Bruggen, Casey E Sheehy, Sirima Kraisin, Liesbeth Frederix, Denisa D Wagner

J Thromb Haemost· May 2024

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Inhibition of protein arginine deiminase 4 prevents inflammation-mediated heart failure in arthritis.
Lukas A Heger, Nicolas Schommer, Shoichi Fukui, Stijn Van Bruggen, Casey E Sheehy, Denisa D Wagner

Life Sci Alliance· October 2023

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NLRP3 is essential for neutrophil polarization and chemotaxis in response to leukotriene B4 gradient.
Stijn Van Bruggen, Pierre-André Jarrot, Eline Thomas, Casey E Sheehy, Camila M S Silva, Denisa D Wagner

Proc Natl Acad Sci U S A· August 2023

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Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4.
Chandru Gajendran, Shoichi Fukui, Naveen M Sadhu, Mohammed Zainuddin, Sridharan Rajagopal, Denisa D Wagner

Sci Rep· February 2023

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NLRP3 inflammasome activation in neutrophils directs early inflammatory response in murine peritonitis.
Saeko Fukui, Shoichi Fukui, Stijn Van Bruggen, Lai Shi, Casey E Sheehy, Denisa D Wagner

Sci Rep· December 2022

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Anti-inflammatory protective effect of ADAMTS-13 in murine arthritis models.
Shoichi Fukui, Sarah Gutch, Saeko Fukui, Long Chu, Denisa D Wagner

J Thromb Haemost· October 2022

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Thromboinflammation: From Atherosclerosis to COVID-19.
Denisa D Wagner, Lukas A Heger

Arterioscler Thromb Vasc Biol· September 2022

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The Prominent Role of Hematopoietic Peptidyl Arginine Deiminase 4 in Arthritis: Collagen- and Granulocyte Colony-Stimulating Factor-Induced Arthritis Model in C57BL/6 Mice.
Shoichi Fukui, Sarah Gutch, Saeko Fukui, Deya Cherpokova, Karen Aymonnier, Denisa D Wagner

Arthritis Rheumatol· July 2022

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Neutrophil phenotypes and functions in cancer: A consensus statement.
Daniela F Quail, Borko Amulic, Monowar Aziz, Betsy J Barnes, Evgeniy Eruslanov, Denisa D Wagner

J Exp Med· June 2022

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Inflammasome activation in neutrophils of patients with severe COVID-19.
Karen Aymonnier, Julie Ng, Laura E Fredenburgh, Katherin Zambrano-Vera, Patrick Münzer, Denisa D Wagner

Blood Adv· April 2022

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Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4.
Lai Shi, Karen Aymonnier, Denisa D Wagner

PLoS One· October 2021

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NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions.
Patrick Münzer, Roberto Negro, Shoichi Fukui, Lucas di Meglio, Karen Aymonnier, Denisa D Wagner

Front Immunol· October 2021

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Citrullinated Fibrinogen Renders Clots Mechanically Less Stable, but Lysis-Resistant.
Imre Varjú, Nicoletta Sorvillo, Deya Cherpokova, Ádám Z Farkas, Veronika J Farkas, Denisa D Wagner

Circ Res· July 2021

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The role of platelets in thrombus fibrosis and vessel wall remodeling after venous thrombosis.
Elise DeRoo, Kimberly Martinod, Deya Cherpokova, Tobias Fuchs, Stephen Cifuni, Denisa D Wagner

J Thromb Haemost· February 2021

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Cellular Mechanisms of NETosis.
Hawa Racine Thiam, Siu Ling Wong, Denisa D Wagner, Clare M Waterman

Annu Rev Cell Dev Biol· October 2020

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Reply to Liu: The disassembly of the actin cytoskeleton is an early event during NETosis.
Hawa Racine Thiam, Siu Ling Wong, Rong Qiu, Mark Kittisopikul, Amir Vahabikashi, Denisa D Wagner

Proc Natl Acad Sci U S A· September 2020

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Recombinant human ADAMTS13 treatment and anti-NET strategies enhance skin allograft survival in mice.
Siu Ling Wong, Jeremy Goverman, Caleb Staudinger, Denisa D Wagner

Am J Transplant· April 2020

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NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture.
Hawa Racine Thiam, Siu Ling Wong, Rong Qiu, Mark Kittisopikul, Amir Vahabikashi, Denisa D Wagner

Proc Natl Acad Sci U S A· March 2020

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Resolvin D4 attenuates the severity of pathological thrombosis in mice.
Deya Cherpokova, Charlotte C Jouvene, Stephania Libreros, Elise P DeRoo, Long Chu, Denisa D Wagner

Blood· October 2019

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Extracellular DNA NET-Works With Dire Consequences for Health.
Nicoletta Sorvillo, Deya Cherpokova, Kimberly Martinod, Denisa D Wagner

Circ Res· August 2019

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