Publications by authors named "Dennis Carson"

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FZD7 expression marks mammary tumor-initiating cells.
Christina C N Wu, Naycari De Luna, Erin Hairston, Erin D Jeffs, Ashley Key, Dennis A Carson

Proc Natl Acad Sci U S A· November 2025

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Enhancing vaccine immunogenicity through heterologous prime-boost regimen with multiple nasal boosting with liposomal TLR7 ligand.
Tomoko Hayashi, Shiyin Yao, Fumi Sato-Kaneko, Renna Cozza, Hiroyuki Baba, Dennis A Carson

Vaccine· October 2025

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Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy.
Mayumi Niimura, Yasuhisa Sakamoto, Mayuko Shimoda, Narumi Harada, Ayato Maeda, Dennis A Carson

Commun Med (Lond)· August 2025

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Design and Application of Conjugatable Small Molecule Toll-Like Receptor 4 Ligands.
Yutaro Mahara, Issa Fukuda, Ryuho Tanaka, Shin-Ya Oyama, Hiroyuki Shinchi, Dennis A Carson

Bioconjug Chem· July 2025

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Structure-Activity Relationship Studies in Benzothiadiazoles as Novel Vaccine Adjuvants.
Masiel M Belsuzarri, Yukiya Sako, Tyler D Brown, Michael Chan, Renna Cozza, Dennis A Carson

J Med Chem· August 2024

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Identification of a Novel Small Molecule That Enhances the Release of Extracellular Vesicles with Immunostimulatory Potency via Induction of Calcium Influx.
Yukiya Sako, Fumi Sato-Kaneko, Nikunj M Shukla, Shiyin Yao, Masiel M Belsuzarri, Dennis A Carson

ACS Chem Biol· April 2023

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Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model.
Jayanth S Shankara Narayanan, Tomoko Hayashi, Suna Erdem, Sara McArdle, Herve Tiriac, Dennis Carson

J Immunother Cancer· January 2023

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A Dual Adjuvant System for Intranasal Boosting of Local and Systemic Immunity for Influenza Vaccination.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Yukiya Sako, Jasmine Jin, Dennis A Carson

Vaccines (Basel)· October 2022

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Glyco-Nanoadjuvants: Impact of Linker Length for Conjugating a Synthetic Small-Molecule TLR7 Ligand to Glyco-Nanoparticles on Immunostimulatory Effects.
Hiroyuki Shinchi, Fumikazu Komaki, Masaharu Yuki, Haruka Ohara, Naohiro Hayakawa, Dennis A Carson

ACS Chem Biol· April 2022

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A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity.
Nikunj M Shukla, Fumi Sato-Kaneko, Shiyin Yao, Minya Pu, Michael Chan, Dennis A Carson

Front Pharmacol· April 2022

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A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models.
Myan Do, Christina C N Wu, Pooja R Sonavane, Edwin F Juarez, Stephen R Adams, Dennis A Carson

Mol Cancer Ther· January 2022

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Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity.
Tetsuya Saito, Nikunj M Shukla, Fumi Sato-Kaneko, Yukiya Sako, Tadashi Hosoya, Dennis A Carson

ACS Chem Biol· January 2022

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Small Molecule Potentiator of Adjuvant Activity Enhancing Survival to Influenza Viral Challenge.
Tetsuya Saito, Yukiya Sako, Fumi Sato-Kaneko, Tadashi Hosoya, Shiyin Yao, Dennis A Carson

Front Immunol· December 2021

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Resistance to sliding of orthodontic archwires under increasing applied moments.
Ahmed Youssef, Carson Dennis, John P Beyer, Thorsten Grünheid

J Appl Biomater Funct Mater· October 2021

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Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation.
Nikunj M Shukla, Michael Chan, Fitzgerald S Lao, Paul J Chu, Masiel Belsuzarri, Dennis A Carson

Bioorg Med Chem· August 2021

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Mitochondria-dependent synthetic small-molecule vaccine adjuvants for influenza virus infection.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Jason Nan, Jonathan Shpigelman, Dennis A Carson

Proc Natl Acad Sci U S A· June 2021

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Editorial: Wnt Signaling in Immune Cell Regulation During Microbial Infection and Cancer.
Antje Blumenthal, Elena Martin-Orozco, Jere W McBride, Dennis A Carson, Malini Sen

Front Immunol· April 2021

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A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity.
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S Lao, Jonathan Shpigelman, Karen Messer, Dennis A Carson

Front Immunol· April 2021

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Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release.
Jonathan Shpigelman, Fitzgerald S Lao, Shiyin Yao, Chenyang Li, Tetsuya Saito, Dennis A Carson

Front Pharmacol· April 2021

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Glyco-Nanoadjuvants: Sugar Structures on Carriers of a Small Molecule TLR7 Ligand Affect Their Immunostimulatory Activities.
Hiroyuki Shinchi, Masaharu Yuki, Takayoshi Yamauchi, Mayumi Niimura, Masahiro Wakao, Dennis A Carson

ACS Appl Bio Mater· March 2021

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Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
Qinglan Wang, So Yeon Kim, Hiroshi Matsushita, Zhijun Wang, Vijay Pandyarajan, Dennis A Carson

Proc Natl Acad Sci U S A· January 2021

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Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells.
Diana Gumber, Myan Do, Neya Suresh Kumar, Pooja R Sonavane, Christina C N Wu, Dennis Carson

Elife· December 2020

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Identification of Compounds With Glucocorticoid Sparing Effects on Suppression of Chemokine and Cytokine Production by Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Tadashi Hosoya, Nikunj M Shukla, Yuya Fujita, Shiyin Yao, Fitzgerald S Lao, Dennis A Carson

Front Pharmacol· December 2020

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Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Ching-Hsin Huang, Natalie Mendez, Oscar Hernandez Echeagaray, Joi Weeks, James Wang, Dennis A Carson

Adv Ther (Weinh)· June 2020

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Synthetic and immunological studies on the OCT4 immunodominant motif antigen-based anti-cancer vaccine.
Tingting Chen, Kan Liu, Jiangyao Xu, Tianying Zhan, Maixian Liu, Dennis A Carson

Cancer Biol Med· February 2020

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