Publications by authors named "Dennis Pedersen"

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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration.
Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel

MAbs· October 2024

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Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Siddharth Jindal, Dennis Vestergaard Pedersen, Nimish Gera, Julian Chandler, Rekha Patel

Mol Immunol· January 2024

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Bispecific Complement Engagers for Targeted Complement Activation.
Dennis V Pedersen, Heidi Gytz, Mikael B L Winkler, Alessandra Zarantonello, Niklas Baumann

J Immunol· August 2023

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Nanobody-mediated complement activation to kill HIV-infected cells.
Maria Lange Pedersen, Dennis Vestergaard Pedersen, Mikael Becher Lykkegaard Winkler, Heidi Gytz Olesen, Ole Schmeltz Søgaard

EMBO Mol Med· April 2023

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Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond.
Dennis Vestergaard Pedersen, Josefine Lorentzen, Gregers Rom Andersen

Immunol Rev· January 2023

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Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging.
Josefine Lorentzen, Dennis Vestergaard Pedersen, Trine Amalie Fogh Gadeberg, Gregers Rom Andersen

Protein Sci· October 2022

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Methodology to identify optimal subject-specific laxity tests to stretch individual parts of knee ligaments.
Michael Skipper Andersen, Dennis Pedersen

Med Eng Phys· September 2022

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Measuring Knee Joint Laxity in Three Degrees-of-Freedom In Vivo Using a Robotics- and Image-Based Technology.
Jana Kümmerlin, Hannah Katharina Fabro, Peter Heide Pedersen, Kenneth Krogh Jensen, Dennis Pedersen

J Biomech Eng· August 2022

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Quantification of the pro-form of human complement component factor D (adipsin).
Maiken Lumby Henriksen, Christian Nielsen, Dennis Pedersen, Gregers Rom Andersen, Steffen Thiel

J Immunol Methods· August 2022

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Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Katharina Braunger, Jiyoon Ahn, Matthijs M Jore, Steven Johnson, Terence T L Tang, Dennis V Pedersen

Nat Commun· January 2022

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A Methodology to Evaluate the Effects of Kinematic Measurement Uncertainties on Knee Ligament Properties Estimated From Laxity Measurements.
Michael Skipper Andersen, Christine Mary Dzialo, Marco Antonio Marra, Dennis Pedersen

J Biomech Eng· June 2021

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Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Nick S Laursen, Dennis V Pedersen, Heidi Gytz, Alessandra Zarantonello, Jens Magnus Bernth Jensen

Front Immunol· May 2021

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Properdin oligomers adopt rigid extended conformations supporting function.
Dennis V Pedersen, Martin Nors Pedersen, Sofia Mm Mazarakis, Yong Wang, Kresten Lindorff-Larsen

Elife· January 2021

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A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Henrik Pedersen, Rasmus K Jensen, Jens Magnus B Jensen, Rachel Fox, Dennis V Pedersen

J Immunol· October 2020

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Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Dennis V Pedersen, Trine A F Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram

Front Immunol· September 2020

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Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement.
Jie Zhang, Lihong Song, Dennis V Pedersen, Anna Li, John D Lambris

Elife· September 2020

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Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement.
Dennis V Pedersen, Thies Rösner, Annette G Hansen, Kasper R Andersen, Steffen Thiel

Mol Immunol· August 2020

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Crystallization and X-ray analysis of monodisperse human properdin.
Dennis Vestergaard Pedersen, Margot Revel, Trine Amalie Fogh Gadeberg, Gregers Rom Andersen

Acta Crystallogr F Struct Biol Commun· February 2019

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Functional and structural insight into properdin control of complement alternative pathway amplification.
Dennis V Pedersen, Lubka Roumenina, Rasmus K Jensen, Trine Af Gadeberg, Chiara Marinozzi

EMBO J· April 2017

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Structural insight into proteolytic activation and regulation of the complement system.
Janus A Schatz-Jakobsen, Dennis V Pedersen, Gregers R Andersen

Immunol Rev· November 2016

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Microbial growth studies in biodiesel blends.
Gitte Sørensen, Dennis V Pedersen, Anna K Nørgaard, Ketil B Sørensen, Sune D Nygaard

Bioresour Technol· April 2011

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