Publications by authors named "Dennis R Koop"

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria.
Martin J Smilkstein, Sovitj Pou, Alina Krollenbrock, Lisa A Bleyle, Rozalia A Dodean, Dennis R Koop

Malar J· August 2019

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Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis.
Mark Asquith, Sean Davin, Patrick Stauffer, Claire Michell, Cathleen Janowitz, Dennis R Koop

Arthritis Rheumatol· October 2017

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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Lisa Frueh, Yuexin Li, Michael W Mather, Qigui Li, Sovitj Pou, Dennis R Koop

ACS Infect Dis· October 2017

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A comparison of salivary testosterone measurement using immunoassays and tandem mass spectrometry.
Keith M Welker, Bethany Lassetter, Cassandra M Brandes, Smrithi Prasad, Dennis R Koop

Psychoneuroendocrinology· September 2016

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A role for adenine nucleotides in the sensing mechanism to purine starvation in Leishmania donovani.
Jessica L Martin, Phillip A Yates, Jan M Boitz, Dennis R Koop, Audrey L Fulwiler

Mol Microbiol· July 2016

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Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis.
Marie H Foss, Sovitj Pou, Patrick M Davidson, Jennifer L Dunaj, Rolf W Winter, Dennis R Koop

ACS Infect Dis· July 2016

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A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer.
Joshi J Alumkal, Rachel Slottke, Jacob Schwartzman, Ganesh Cherala, Myrna Munar, Dennis R Koop

Invest New Drugs· April 2015

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Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.
Thomas O'Hare, Christopher A Eide, Anupriya Agarwal, Lauren T Adrian, Matthew S Zabriskie, Dennis R Koop

Cancer Res· June 2013

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Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry.
Dennis R Koop, Lisa A Bleyle, Myrna Munar, Ganesh Cherala, Amira Al-Uzri

J Chromatogr B Analyt Technol Biomed Life Sci· May 2013

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Naloxone pro-drug rescues morphine induced respiratory depression in Sprague-Dawley rats.
Michael Wallisch, Nehad M El Rody, Baohua Huang, Dennis R Koop, James R Baker

Respir Physiol Neurobiol· January 2012

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The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1.
Jeffrey P Jones, Carolyn A Joswig-Jones, Michelle Hebner, Yuzhuo Chu, Dennis R Koop

Chem Biol Interact· August 2011

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Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice.
Blair U Bradford, Eric F Lock, Oksana Kosyk, Sungkyoon Kim, Takeki Uehara, Dennis R Koop

Toxicol Sci· March 2011

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Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination.
YongQiang Wang, Shenheng Guan, Poulomi Acharya, Dennis R Koop, Yi Liu

J Biol Chem· March 2011

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Optimization of endochin-like quinolones for antimalarial activity.
Rolf Winter, Jane X Kelly, Martin J Smilkstein, David Hinrichs, Dennis R Koop

Exp Parasitol· February 2011

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Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.
Christine L Powell, Blair U Bradford, Christopher Patrick Craig, Masato Tsuchiya, Takeki Uehara, Dennis R Koop

Toxicol Sci· May 2010

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Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters.
Vijayshree Yadav, Gail H Marracci, Myrna Y Munar, Ganesh Cherala, Lauren E Stuber, Dennis R Koop

Mult Scler· April 2010

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Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro.
Stuart J McDougall, James H Peters, Lia LaBrant, Xin Wang, Dennis R Koop

PLoS One· October 2008

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Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia.
Wenri Zhang, Takashi Otsuka, Nobuo Sugo, Ardi Ardeshiri, Yazan K Alhadid, Dennis R Koop

Stroke· July 2008

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Isoflurane differentially modulates inhibitory and excitatory synaptic transmission to the solitary tract nucleus.
James H Peters, Stuart J McDougall, David Mendelowitz, Dennis R Koop, Michael C Andresen

Anesthesiology· April 2008

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Alcohol metabolism's damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochrome P450 2E1.
Dennis R Koop

Alcohol Res Health· October 2007

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Effect of pregnancy on the pharmacokinetics of paclitaxel: a case report.
Jennifer L Lycette, Carrie L Dul, Myrna Munar, Donna Belle, Stephen Y Chui, Dennis R Koop

Clin Breast Cancer· October 2006

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Steatohepatitis induced by intragastric overfeeding in mice.
Qing-Gao Deng, Hongyun She, Jason H Cheng, Samuel W French, Dennis R Koop

Hepatology· October 2005

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Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.
Amala Soumyanath, Yong-Ping Zhong, Sandra A Gold, Xiaolin Yu, Dennis R Koop

J Pharm Pharmacol· September 2005

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Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver.
Blair U Bradford, Hiroshi Kono, Fuyumi Isayama, Oksana Kosyk, Michael D Wheeler, Dennis R Koop

Hepatology· February 2005

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A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer.
Charles D Blanke, Nora C Mattek, Thomas G Deloughery, Dennis R Koop

Prostaglandins Other Lipid Mediat· January 2005

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