Publications by authors named "Deok Yong Sim"

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STK32C as a Therapeutic Target in Colorectal Cancer via HSP90-PI3K/AKT/mTOR Signaling.
Chi-Hoon Ahn, Ji Eon Park, Deok Yong Sim, Su-Yeon Park, Hyun Ju Cha

Int J Biol Sci· November 2025

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ZBTB7B modulates the androgen receptor as an upstream regulator via colocalization and direct binding in LNCaP prostate cancer cells.
Eunji Im, Su-Yeon Park, Deok-Yong Sim, Ah Reum Cho, Bum Ju Kil

Transl Cancer Res· November 2025

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Inhibition of LGR5/β-Catenin Axis and Activation of miR134 Are Critically Involved in Apoptotic Effect of Sanggenol L in Hepatocellular Carcinoma.
Jisung Hwang, Deok Yong Sim, Chi-Hoon Ahn, Su-Yeon Park, Jin-Suk Koo

Biol Pharm Bull· May 2025

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Crucial Role of c-Myc/Monocarboxylate Transporter 4 Signaling in Capsaicin Induced Apoptotic and Anti-Warburg Effects in Hepatocellular Carcinoma.
Jin Young Suh, Deok Yong Sim, Chi-Hoon Ahn, Su-Yeon Park, Bum-Sang Shim

Phytother Res· January 2025

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Anti-Warburg Mechanism of Ginsenoside F2 in Human Cervical Cancer Cells via Activation of miR193a-5p and Inhibition of β-Catenin/c-Myc/Hexokinase 2 Signaling Axis.
Nari Shin, Hyo-Jung Lee, Deok Yong Sim, Chi-Hoon Ahn, Su-Yeon Park

Int J Mol Sci· August 2024

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Negative Regulation of CPSF6 Suppresses the Warburg Effect and Angiogenesis Leading to Tumor Progression Via c-Myc Signaling Network: Potential Therapeutic Target for Liver Cancer Therapy.
Deok Yong Sim, Hyo-Jung Lee, Chi-Hoon Ahn, JiEon Park, Su-Yeon Park

Int J Biol Sci· July 2024

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Apoptotic Effect of Isoimpertorin via Inhibition of c-Myc and SIRT1 Signaling Axis.
Hwan-Joo Ko, Su-Yeon Park, Deok Yong Sim, Sung-Hoon Kim, Soyoung Hur

Int J Mol Sci· April 2024

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Inhibition of glycolysis and SIRT1/GLUT1 signaling ameliorates the apoptotic effect of Leptosidin in prostate cancer cells.
Youngsang Park, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn

Phytother Res· March 2024

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The microRNA-193a-5p induced ROS production and disturbed colocalization between STAT3 and androgen receptor play critical roles in cornin induced apoptosis.
Jhin-Baek Choi, Deok Yong Sim, Hyo-Jung Lee, Ji Eon Park, Chi-Hoon Ahn

Phytother Res· February 2024

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Extract Induces Apoptosis via Generation of Reactive Oxygen Species and Inhibition of Heat Shock Protein 27 and Androgen Receptor in Prostate Cancers.
Seok-Young Kim, Ji Eon Park, Hyo-Jung Lee, Deok Yong Sim, Chi-Hoon Ahn

Int J Mol Sci· February 2024

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Apoptotic and anti-Warburg effect of Morusin via ROS mediated inhibition of FOXM1/c-Myc signaling in prostate cancer cells.
Ja Il Koo, Deok Yong Sim, Hyo-Jung Lee, Chi-Hoon Ahn, JiEon Park

Phytother Res· October 2023

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Anti-Warburg effect via generation of ROS and inhibition of PKM2/β-catenin mediates apoptosis of lambertianic acid in prostate cancer cells.
Ji-Na Pak, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn

Phytother Res· September 2023

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Honokiol inhibits epithelial-mesenchymal transition and hepatic fibrosis via activation of Ecadherin/GSK3β/JNK and inhibition of AKT/ERK/p38/β-catenin/TMPRSS4 signaling axis.
Jae Hwa Seo, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn

Phytother Res· September 2023

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The Apoptotic and Anti-Warburg Effects of Brassinin in PC-3 Cells via Reactive Oxygen Species Production and the Inhibition of the c-Myc, SIRT1, and β-Catenin Signaling Axis.
Hyeon Hee Kwon, Chi-Hoon Ahn, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park

Int J Mol Sci· September 2023

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Antioxidant-Based Preventive Effect of Phytochemicals on Anticancer Drug-Induced Hepatotoxicity.
Ji Eon Park, Chi-Hoon Ahn, Hyo-Jung Lee, Deok Yong Sim, Su Yeon Park

Antioxid Redox Signal· June 2023

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SH-PRO extract alleviates benign prostatic hyperplasia via ROS-mediated activation of PARP/caspase 3 and inhibition of FOXO3a/AR/PSA signaling in vitro and in vivo.
Ji Eon Park, Woo-Cheol Shin, Hyo-Jung Lee, Dahye Yoon, Deok Yong Sim

Phytother Res· February 2023

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The underlying hepatoprotective mechanism of PKC#963 in alcohol or carbon tetrachloride induced liver injury via inhibition of iNOS, COX-2, and p-STAT3 and enhancement of SOD and catalase.
Dong Sub Kim, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Youngsang Park

Phytother Res· February 2023

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Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells.
Jin Young Suh, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn

Phytother Res· January 2023

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Antitumor mechanism of combination of Angelica gigas and Torilis japonica in LNCaP prostate cancer cells via G1 arrest and inhibition of Wnt/β-catenin and androgen receptor signaling.
Dong Hee Kim, Eunji Im, Dae Young Lee, Hyo-Jung Lee, Deok Yong Sim

Phytother Res· July 2022

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The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling.
Hyungjin Kim, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn

Int J Mol Sci· June 2022

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Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of HAX, CHK2 and p53.
Ji-Hyun Kim, Eunji Im, Jihyun Lee, Hyo-Jung Lee, Deok Yong Sim

Cells· April 2022

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Moracin D induces apoptosis in prostate cancer cells via activation of PPAR gamma/PKC delta and inhibition of PKC alpha.
Jae Seok Yoon, Hyo-Jung Lee, Deok Yong Sim, Eunji Im, Ji Eon Park

Phytother Res· December 2021

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UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11.
Ju-Ha Kim, Ji Hoon Jung, Hyo-Jung Lee, Deok-Yong Sim, Eunji Im

Cancers (Basel)· September 2021

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Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer.
Ah-Reum Cho, Woon-Yi Park, Hyo-Jung Lee, Deok-Yong Sim, Eunji Im

Int J Mol Sci· September 2021

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Inhibition of STAT3/PD-L1 and Activation of miR193a-5p Are Critically Involved in Apoptotic Effect of Compound K in Prostate Cancer Cells.
Jae-Hee Lee, Dae-Young Lee, Hyo-Jung Lee, Eunji Im, Deok-Yong Sim

Cells· August 2021

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