Publications by authors named "Derek MacMillan"

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LEKTI-Grafted Sunflower Trypsin Inhibitor: A Potential Therapeutic for Skin Diseases.
Jeffrey Mah, Vignesh Jayarajan, Xin Huang, Wei-Li Di, Derek Macmillan

J Med Chem· November 2025

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Investigation of acyl transfer auxiliary-assisted glycoconjugation for glycoprotein semi-synthesis.
Kudakwashe Nyandoro, Charles M G Lamb, Haoran Yu, Jian Shi, Derek Macmillan

Org Biomol Chem· November 2022

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Novel electrochemically-mediated peptide dethiylation in processes relevant to native chemical ligation.
Charles M G Lamb, Jian Shi, Jonathan D Wilden, Derek Macmillan

Org Biomol Chem· September 2022

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Rapid access to Asp/Glu sidechain hydrazides as thioester precursors for peptide cyclization and glycosylation.
Natalie G Barnes, Kudakwashe Nyandoro, Hanzhang Jin, Derek Macmillan

Chem Commun (Camb)· February 2021

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Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.
Yanan Zhu, Joanne Underwood, Derek Macmillan, Leila Shariff, Ryan O'Shaughnessy

J Allergy Clin Immunol· November 2017

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Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases.
Wenjie Chen, Veronica A Kinsler, Derek Macmillan, Wei-Li Di

PLoS One· June 2017

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Expanding the scope of N → S acyl transfer in native peptide sequences.
Ben Cowper, Leila Shariff, Wenjie Chen, Samantha M Gibson, Wei-Li Di, Derek Macmillan

Org Biomol Chem· July 2015

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Examination of mercaptobenzyl sulfonates as catalysts for native chemical ligation: application to the assembly of a glycosylated Glucagon-Like Peptide 1 (GLP-1) analogue.
Ben Cowper, Tsz Mei Sze, Bhavesh Premdjee, Aileen F Bongat White, Andrew Hacking, Derek Macmillan

Chem Commun (Camb)· February 2015

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The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.
Silke M Currie, Emily Gwyer Findlay, Brian J McHugh, Annie Mackellar, Tian Man, Derek Macmillan

PLoS One· April 2014

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Cysteine promoted C-terminal hydrazinolysis of native peptides and proteins.
Anna L Adams, Ben Cowper, Rachel E Morgan, Bhavesh Premdjee, Stephen Caddick, Derek Macmillan

Angew Chem Int Ed Engl· December 2013

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Making ends meet: chemically mediated circularization of recombinant proteins.
Ben Cowper, David J Craik, Derek Macmillan

Chembiochem· May 2013

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Investigation of peptide thioester formation via N→Se acyl transfer.
Anna L Adams, Derek Macmillan

J Pept Sci· February 2013

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Small-molecule inhibition of c-MYC:MAX leucine zipper formation is revealed by ion mobility mass spectrometry.
Sophie R Harvey, Massimiliano Porrini, Christiane Stachl, Derek MacMillan, Giovanna Zinzalla

J Am Chem Soc· November 2012

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The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Stephanie Jungmichel, Julie A Clapperton, Janette Lloyd, Flurina J Hari, Christoph Spycher, Derek MacMillan

Nucleic Acids Res· May 2012

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Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer.
Derek Macmillan, Anna Adams, Bhavesh Premdjee

Isr J Chem· November 2011

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Native N-glycopeptide thioester synthesis through N→S acyl transfer.
Bhavesh Premdjee, Anna L Adams, Derek Macmillan

Bioorg Med Chem Lett· September 2011

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Synthesis of cyclic peptides through an intramolecular amide bond rearrangement.
Derek Macmillan, Martin De Cecco, Natalie L Reynolds, Luiz F A Santos, Perdita E Barran

Chembiochem· September 2011

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Semi-synthesis of glycoproteins from E. coli through native chemical ligation.
Jonathan P Richardson, Derek Macmillan

Methods Mol Biol· March 2011

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Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer.
Jinit Masania, Jiejin Li, Stephen J Smerdon, Derek Macmillan

Org Biomol Chem· November 2010

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Towards biomolecular assembly employing extended native chemical ligation in combination with thioester synthesis using an N-->S acyl shift.
Tom Ackrill, David W Anderson, Derek Macmillan

Biopolymers· September 2010

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Peptide fragments of a beta-defensin derivative with potent bactericidal activity.
Natalie L Reynolds, Martin De Cecco, Karen Taylor, Chloe Stanton, Fiona Kilanowski, Derek Macmillan

Antimicrob Agents Chemother· May 2010

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Peptide and protein thioester synthesis via N-->S acyl transfer.
Jaskiranjit Kang, Derek Macmillan

Org Biomol Chem· May 2010

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Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements.
Bryan J McCullough, Jason M Kalapothakis, Wutharath Chin, Karen Taylor, David J Clarke, Derek MacMillan

Phys Chem Chem Phys· April 2010

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Exploring neoglycoprotein assembly through native chemical ligation using neoglycopeptide thioesters prepared via N-->S acyl transfer.
Jonathan P Richardson, Chung-Hei Chan, Javier Blanc, Mona Saadi, Derek Macmillan

Org Biomol Chem· March 2010

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Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives.
Satpal Virdee, Derek Macmillan, Gabriel Waksman

Chem Biol· March 2010

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