Publications by authors named "Derek R Clements"

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CD301b+ monocyte-derived dendritic cells mediate resistance to radiotherapy.
Sirimuvva Tadepalli, Derek R Clements, Hayley M Raquer-McKay, Anja Lüdtke, Sanjana Saravanan

J Exp Med· June 2025

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Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.
James Zengel, Yu Xin Wang, Jai Woong Seo, Ke Ning, James N Hamilton, Derek R Clements

Nat Methods· July 2023

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Rapid recruitment and IFN-I-mediated activation of monocytes dictate focal radiotherapy efficacy.
Sirimuvva Tadepalli, Derek R Clements, Sanjana Saravanan, Rebeca Arroyo Hornero, Anja Lüdtke

Sci Immunol· June 2023

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Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy.
Anastasia Prokopi, Christoph H Tripp, Bart Tummers, Florian Hornsteiner, Sarah Spoeck, Derek R Clements

J Immunother Cancer· January 2021

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Quantitative Proteome Responses to Oncolytic Reovirus in GM-CSF- and M-CSF-Differentiated Bone Marrow-Derived Cells.
Michael A Giacomantonio, Andra M Sterea, Youra Kim, Joao A Paulo, Derek R Clements

J Proteome Res· February 2020

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Single Amino Acid Differences between Closely Related Reovirus T3D Lab Strains Alter Oncolytic Potency and .
Adil Mohamed, Derek R Clements, Shashi A Gujar, Patrick W Lee, James R Smiley

J Virol· January 2020

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Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus.
Barry E Kennedy, John Patrick Murphy, Derek R Clements, Prathyusha Konda, Namit Holay

Cancer Res· August 2019

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Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy.
J Patrick Murphy, Youra Kim, Derek R Clements, Prathyusha Konda, Heiko Schuster

J Proteome Res· June 2019

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TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway.
Shekoufeh Almasi, Clara Yu Long, Andra Sterea, Derek Richard Clements, Shashi Gujar

Cell Physiol Biochem· April 2019

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TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway.
Shekoufeh Almasi, Andra M Sterea, Wasundara Fernando, Derek R Clements, Paola Marcato

Sci Rep· March 2019

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The NAD Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis.
J Patrick Murphy, Michael A Giacomantonio, Joao A Paulo, Robert A Everley, Barry E Kennedy, Derek R Clements

Cell Rep· August 2018

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Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors.
Jonathan G Pol, Sarah Lévesque, Samuel T Workenhe, Shashi Gujar, Fabrice Le Boeuf, Derek R Clements

Oncoimmunology· August 2018

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Epigenetic Silencing of TAP1 in Aldefluor Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion.
Mohammad Sultan, Dejan Vidovic, Arianne S Paine, Thomas T Huynh, Krysta M Coyle, Derek R Clements

Stem Cells· May 2018

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Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis.
Jordan R Warford, Anna-Claire Lamport, Derek R Clements, Alicia Malone, Barry E Kennedy

Acta Neuropathol Commun· January 2018

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Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages.
Derek R Clements, John Patrick Murphy, Andra Sterea, Barry E Kennedy, Youra Kim

J Proteome Res· September 2017

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Autophagic homeostasis is required for the pluripotency of cancer stem cells.
Tanveer Sharif, Emma Martell, Cathleen Dai, Barry E Kennedy, Patrick Murphy, Derek R Clements

Autophagy· February 2017

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Dendritic Cells in Oncolytic Virus-Based Anti-Cancer Therapy.
Youra Kim, Derek R Clements, Andra M Sterea, Hyun Woo Jang, Shashi A Gujar

Viruses· December 2015

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All that glitters is not gold: the need to consider desirable and undesirable immune aspects of oncolytic virus therapy.
Derek R Clements, Youra Kim, Shashi A Gujar, Patrick Wk Lee

Oncoimmunology· June 2015

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Newly recruited CD11b+, GR-1+, Ly6C(high) myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus.
Derek R Clements, Andra M Sterea, Youra Kim, Erin Helson, Cheryl A Dean

J Immunol· May 2015

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