Publications by authors named "Derek Rhoades"

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Pharmacological targeting of RIG-I can selectively activate the integrated stress response.
Caroline A Cuoco, Wen Ren, Kelsey R Baron, Sakina Gologo, Valerie Perea, Derek Rhoades

Sci Adv· October 2025

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Autophagy activator AA-20 improves proteostasis and extends lifespan.
Ee Phie Tan, Nora Lyang, Saam Doroodian, Pablo Sanz-Martinez, Jin Xu, Derek Rhoades

Proc Natl Acad Sci U S A· August 2025

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Electrostatic Effects on Tau Nanocondensates.
Phoebe S Tsoi, Lathan Lucas, Derek Rhoades, Josephine C Ferreon, Allan Chris M Ferreon

Biomolecules· March 2025

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Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains.
Oren L Lederberg, Nicholas L Yan, Julian Sanchez, Wen Ren, Carl Ash, Derek Rhoades

J Med Chem· December 2024

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A PIKfyve modulator combined with an integrated stress response inhibitor to treat lysosomal storage diseases.
William C Hou, Lynée A Massey, Derek Rhoades, Yin Wu, Wen Ren

Proc Natl Acad Sci U S A· August 2024

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Expedient Total Syntheses of Pladienolide-Derived Spliceosome Modulators.
Derek Rhoades, Arnold L Rheingold, Bert W O'Malley, Jin Wang

J Am Chem Soc· April 2021

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Total Syntheses of Thailanstatins A-C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents.
K C Nicolaou, Derek Rhoades, S Mothish Kumar

J Am Chem Soc· July 2018

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12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents.
K C Nicolaou, Derek Rhoades, Yanping Wang, Ruoli Bai, Ernest Hamel

J Am Chem Soc· May 2017

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Total Synthesis of Thailanstatin A.
K C Nicolaou, Derek Rhoades, Manjunath Lamani, Manas R Pattanayak, S Mothish Kumar

J Am Chem Soc· June 2016

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Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues.
K C Nicolaou, Derek Rhoades, Yanping Wang, Sotirios Totokotsopoulos, Ruoli Bai

ChemMedChem· December 2015

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A comprehensive ligand based mapping of the σ₂ receptor binding pocket.
Derek J Rhoades, David H Kinder, Tarek M Mahfouz

Med Chem· September 2014

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Withdrawal effect of chronic amphetamine exposure during adolescence on complex maze performance.
Daniel M Krall, Stephanie L Lim, Abby M Cooper, Paul W Burleson, Derek J Rhoades

Addict Biol· July 2014

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Synthesis of macroheterocycles through intramolecular oxidative coupling of furanoid β-ketoesters.
K C Nicolaou, Christopher R H Hale, Christian Ebner, Christian Nilewski, Christopher F Ahles, Derek Rhoades

Angew Chem Int Ed Engl· May 2012

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