Publications by authors named "Derek Taylor"

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A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non-small cell lung cancer.
Brynne Raines, Stephanie Tseng-Rogenski, Amanda C Dowdican, Irene Peris, Matthew Hinderman, Derek J Taylor

J Clin Invest· December 2025

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Multivalent Nanobodies for Potent and Broad Neutralization of Toxins.
Yong Joon Jeffrey Kim, Nicholas R Walton, Wei Huang, Madison Lee, Yufei Xiang, Derek J Taylor

bioRxiv· December 2025

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The structure-function relationship of ATE1 R-transferase of the autophagic Arg/N-degron pathway.
Su Bin Kim, Ji Su Lee, Xin Lan, Wei Huang, Derek J Taylor

Autophagy· October 2025

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Regulatory mechanisms of PP2A complex assembly driven by physicochemical differences in A-subunit isoforms.
Alexander Day, Wei Huang, Daniel Leonard, Caitlin M O'Connor, Goutham Narla, Derek J Taylor

Structure· October 2025

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15-PGDH inhibition enhances hematopoietic regeneration during aging.
Rahul Chaudhary, Brittany A Cordova, Marcus Hong, Bailey R Klein, Lyannah A Contreras, Derek J Taylor

Stem Cells· September 2025

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Cryo-EM structures reveal the PP2A-B55α and Eya3 interaction that can be disrupted by a peptide inhibitor.
Shasha Shi, Xueni Li, Christopher Alderman, Lars Wick, Wei Huang, Derek J Taylor

J Biol Chem· July 2025

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Superimmunity by pan-sarbecovirus nanobodies.
Yufei Xiang, Wei Huang, Hejun Liu, Zhe Sang, Sham Nambulli, Derek J Taylor

Cell Rep· July 2025

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Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling.
Moeez Rathore, Kimberly Curry, Wei Huang, Michel'le Wright, Daniel Martin, Derek Taylor

Gastroenterology· February 2025

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Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer.
Terrance J Haanen, Sophie Boock, Catherine G Callahan, Irene Peris, Kaitlin P Zawacki, Derek J Taylor, Sarah E Taylor

Cancer Res· February 2025

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Cryo-EM structures reveal the PP2A-B55α and Eya3 interaction that can be disrupted by a peptide inhibitor.
Shasha Shi, Xueni Li, Christopher Alderman, Wei Huang, Lars Wick, Derek J Taylor

bioRxiv· February 2025

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Adaptive multi-epitope targeting and avidity-enhanced nanobody platform for ultrapotent, durable antiviral therapy.
Yufei Xiang, Jialu Xu, Briana L McGovern, Anna Ranzenigo, Wei Huang, Derek J Taylor

Cell· November 2024

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Genomic transfers help to decipher the ancient evolution of filoviruses and interactions with vertebrate hosts.
Derek J Taylor, Max H Barnhart

PLoS Pathog· September 2024

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Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Xin Lan, Wei Huang, Su Bin Kim, Dechen Fu, Thilini Abeywansha, Derek J Taylor

Nat Commun· July 2024

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Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1.
Kristy Rochon, Brianna L Bauer, Nathaniel A Roethler, Yuli Buckley, Chih-Chia Su, Derek J Taylor

Nat Commun· February 2024

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The specificity landscape of bacterial ribonuclease P.
Alexandra R Chamberlain, Loc Huynh, Wei Huang, Derek J Taylor, Michael E Harris

J Biol Chem· January 2024

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Oligomerization-mediated activation of a short prokaryotic Argonaute.
Zhangfei Shen, Xiao-Yuan Yang, Shiyu Xia, Wei Huang, Derek J Taylor

Nature· September 2023

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Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Reyaz Ur Rasool, Caitlin M O'Connor, Chandan Kanta Das, Mohammed Alhusayan, Brijesh Kumar Verma, Derek J Taylor

Nat Commun· August 2023

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High-resolution structural-omics of human liver enzymes.
Chih-Chia Su, Meinan Lyu, Zhemin Zhang, Masaru Miyagi, Wei Huang, Derek J Taylor

Cell Rep· June 2023

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The structural basis of tRNA recognition by arginyl-tRNA-protein transferase.
Thilini Abeywansha, Wei Huang, Xuan Ye, Allison Nawrocki, Xin Lan, Derek J Taylor

Nat Commun· April 2023

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Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system.
Wei Huang, Hongyun Li, Janna Kiselar, Stephen P Fink, Sagar Regmi, Derek J Taylor

Nat Commun· February 2023

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sp. nov. (Crustacea: Cladocera) an eastern Palearctic montane species with mitochondrial discordance.
Alexey A Kotov, Derek J Taylor

PeerJ· January 2023

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Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Jiaqiang Zhu, Wei Huang, Jing Zhao, Loc Huynh, Derek J Taylor

Nat Commun· August 2022

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Superimmunity by pan-sarbecovirus nanobodies.
Yufei Xiang, Wei Huang, Hejun Liu, Zhe Sang, Sham Nambulli, Derek J Taylor

Cell Rep· June 2022

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Evolution and diversity of inherited viruses in the Nearctic phantom midge, .
Matthew J Ballinger, Rebecca C Christian, Logan D Moore, Derek J Taylor, Afsoon Sabet

Virus Evol· March 2022

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