Publications by authors named "Derin B Keskin"

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CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity.
Robert J Fisher, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Derin B Keskin

JCI Insight· December 2025

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Association of specific HLA alleles in patients with interstitial cystitis suggesting autoimmunity.
Inna Tabansky Stern, Jiayao Wang, Robert M Moldwin, Jason M Kim, Jason H Singh, Derin B Keskin

Front Mol Med· December 2025

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Lymphotoxin-driven cancer cell eradication by tumoricidal CD8 TIL.
Hongyan Xie, Aiping Jiang, Aonkon Dey, Joseph W Dean, Jonathan J Perera, Derin B Keskin

bioRxiv· November 2025

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A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma.
Eryn Blass, Derin B Keskin, Chloe R Tu, Cleo Forman, Allison Vanasse

Cell· September 2025

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Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation.
Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Liang Li, Julia Keating, Derin B Keskin

Nat Biotechnol· June 2025

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HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.
Qinqin Jiang, David A Braun, Karl R Clauser, Vijyendra Ramesh, Nitin H Shirole, Derin B Keskin

Cell· April 2025

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A neoantigen vaccine generates antitumour immunity in renal cell carcinoma.
David A Braun, Giorgia Moranzoni, Vipheaviny Chea, Bradley A McGregor, Eryn Blass, Derin B Keskin

Nature· March 2025

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A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings.
Steven P Treon, Camille N Kotton, David J Park, Giorgia Moranzoni, Camilla K Lemvigh, Derin B Keskin

Front Immunol· February 2025

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CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.
Robert J Fisher, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Derin B Keskin

bioRxiv· December 2024

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Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination.
Yang C Zeng, Olivia J Young, Christopher M Wintersinger, Frances M Anastassacos, James I MacDonald, Derin B Keskin

Nat Nanotechnol· July 2024

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Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Derin B Keskin

ACS Cent Sci· April 2024

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Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ+ T cells targeting multiple myeloma.
Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Derin B Keskin

Blood· March 2024

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CKLF instigates a "cold" microenvironment to promote MYCN-mediated tumor aggressiveness.
Xiaodan Qin, Andrew Lam, Xu Zhang, Satyaki Sengupta, J Bryan Iorgulescu, Derin B Keskin

Sci Adv· March 2024

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Dictionary of immune responses to cytokines at single-cell resolution.
Ang Cui, Teddy Huang, Shuqiang Li, Aileen Ma, Jorge L Pérez, Derin B Keskin

Nature· January 2024

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The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma.
R Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C Gokhale, Derin B Keskin

Cancer Res· December 2023

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Integrated Immunopeptidomic and Proteomic Analysis of COVID-19 lung biopsies.
Shanye Yin, Susan Klaeger, Vipheaviny A Chea, Isabel P Carulli, Suzanna Rachimi, Derin B Keskin

Front Immunol· November 2023

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Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons.
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Derin B Keskin

bioRxiv· September 2023

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Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.
Pavan Bachireddy, Elham Azizi, Cassandra Burdziak, Vinhkhang N Nguyen, Christina S Ennis, Derin B Keskin

Cell Rep· August 2023

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ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
Ines Mota, Enrico Patrucco, Cristina Mastini, Navin R Mahadevan, Tran C Thai, Derin B Keskin

Nat Cancer· July 2023

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Protocol for Classification Single-Cell PBMC Types from Pathological Samples Using Supervised Machine Learning.
Minjie Lyu, Lin Xin, Huan Jin, Lou T Chitkushev, Guanglan Zhang, Derin B Keskin

Methods Mol Biol· June 2023

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YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma.
Thomas C Frost, Ashley K Gartin, Mofei Liu, Jingwei Cheng, Harita Dharaneeswaran, Derin B Keskin

J Clin Invest· March 2023

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Lynch syndrome cancer vaccines: A roadmap for the development of precision immunoprevention strategies.
Shizuko Sei, Aysel Ahadova, Derin B Keskin, Lena Bohaumilitzky, Johannes Gebert

Front Oncol· March 2023

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HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses.
Shira Weingarten-Gabbay, Leah R Pearlman, Da-Yuan Chen, Susan Klaeger, Hannah B Taylor, Derin B Keskin

STAR Protoc· December 2022

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Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders.
Inna Tabansky, Akemi J Tanaka, Jiayao Wang, Guanglan Zhang, Irena Dujmovic, Derin B Keskin

Front Immunol· October 2022

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Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.
Patrick C Lee, Susan Klaeger, Phuong M Le, Keegan Korthauer, Jingwei Cheng, Derin B Keskin

J Clin Invest· July 2022

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