Publications by authors named "Des Jones"

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Characterisation of human in vitro tumour-associated macrophage models to define translational relevance.
Arthur Dyer, Rebecca Dudley, Shreya Ahuja, Clara Alsinet, Pawan Poudel, Des C Jones

Sci Rep· November 2025

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LILRB2 blockade facilitates macrophage repolarization and enhances T cell-mediated antitumor immunity.
Des C Jones, Lorraine Irving, Rebecca Dudley, Seraina Blümli, Marcin Wolny

J Immunother Cancer· April 2025

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Immunomodulation of T- and NK-cell Responses by a Bispecific Antibody Targeting CD28 Homolog and PD-L1.
Madhu Ramaswamy, Taeil Kim, Des C Jones, Hormas Ghadially, Tamer I Mahmoud

Cancer Immunol Res· February 2022

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Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1 Activated T Cells.
Simon J Dovedi, Matthew J Elder, Chunning Yang, Suzanne I Sitnikova, Lorraine Irving, Des C Jones

Cancer Discov· May 2021

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LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation.
Muchaala Yeboah, Charys Papagregoriou, Des C Jones, H T Claude Chan, Guangan Hu

JCI Insight· September 2020

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Interaction of the LILRB1 inhibitory receptor with HLA class Ia dimers.
Diogo Baía, Jordi Pou, Des Jones, Ofer Mandelboim, John Trowsdale

Eur J Immunol· July 2016

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Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8-associated ligand on necrotic glandular epithelial cells.
Des C Jones, Colin R A Hewitt, María R López-Álvarez, Martin Jahnke, Alasdair I Russell

Oncotarget· March 2016

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Expression of the innate immune receptor LILRB5 on monocytes is associated with mycobacteria exposure.
Louise E Hogan, Des C Jones, Rachel L Allen

Sci Rep· February 2016

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TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.
Valeria Radjabova, Piero Mastroeni, Karsten Skjødt, Paola Zaccone, Bernard de Bono, Des C Jones

J Immunol· October 2015

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Surveillance of cell and tissue perturbation by receptors in the LRC.
John Trowsdale, Des C Jones, Alexander D Barrow, James A Traherne

Immunol Rev· September 2015

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LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.
Arman A Bashirova, Enrique Martin-Gayo, Des C Jones, Ying Qi, Richard Apps

PLoS Genet· March 2014

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Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors.
María R López-Álvarez, Des C Jones, Wei Jiang, James A Traherne, John Trowsdale

Immunogenetics· February 2014

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Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.
Mark L Ormiston, Chiwen Chang, Lu L Long, Elaine Soon, Des Jones

Circulation· August 2012

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Characterisation of bovine leukocyte Ig-like receptors.
Louise Hogan, Sabin Bhuju, Des C Jones, Ken Laing, John Trowsdale

PLoS One· July 2012

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Ex vivo functional responses to HLA-G differ between blood and decidual NK cells.
Richard Apps, Andrew Sharkey, Lucy Gardner, Victoria Male, Pippa Kennedy, Des Jones

Mol Hum Reprod· September 2011

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HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding.
Des C Jones, Vasilis Kosmoliaptsis, Richard Apps, Nicolas Lapaque, Isobel Smith

J Immunol· March 2011

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Filament-associated TSGA10 protein is expressed in professional antigen presenting cells and interacts with vimentin.
Ali Roghanian, Des C Jones, Jogi V Pattisapu, Jonathan Wolfe, Neil T Young

Cell Immunol· November 2010

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Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes.
Des C Jones, Ali Roghanian, Damien P Brown, Chiwen Chang, Rachel L Allen

Eur J Immunol· November 2009

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The inhibitory receptor LILRB4 (ILT3) modulates antigen presenting cell phenotype and, along with LILRB2 (ILT4), is upregulated in response to Salmonella infection.
Damien P Brown, Des C Jones, Katie J Anderson, Nicolas Lapaque, Robin A Buerki

BMC Immunol· October 2009

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Salmonella regulates polyubiquitination and surface expression of MHC class II antigens.
Nicolas Lapaque, James L Hutchinson, Des C Jones, Stéphane Méresse, David W Holden

Proc Natl Acad Sci U S A· August 2009

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Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies.
Anita Trundley, Helge Frebel, Des Jones, Chiwen Chang, John Trowsdale

Eur J Immunol· March 2007

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Nature of allelic sequence polymorphism at the KIR3DL3 locus.
Des C Jones, Susan E Hiby, Ashley Moffett, John Trowsdale, Neil T Young

Immunogenetics· August 2006

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The impact of thiopurine S-methyltransferase polymorphisms on azathioprine dose 1 year after renal transplantation.
Margarete A Fabre, Des C Jones, Mike Bunce, Peter J Morris, Peter J Friend

Transpl Int· October 2004

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Genetic determinants of delayed graft function after kidney transplantation.
Shawn D St Peter, Charles J Imber, Des C Jones, Susan V Fuggle, Christopher J Watson

Transplantation· September 2002

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