Publications by authors named "Detlef Obal"

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Opioid Preconditioning in Heart Failure: New Frontier or Old Dog?
Detlef Obal, Yu Liu

Anesth Analg· October 2025

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Pro-Con Debate: Opioids and Perioperative Organ Injury-Friend or Foe?
Detlef Obal, Andrew Notarianni, Loren E Smith, Eric R Gross

Anesth Analg· August 2025

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Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization.
Oscar J Abilez, Huaxiao Yang, Yuan Guan, Mengcheng Shen, Zehra Yildirim, Detlef Obal

Science· June 2025

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Cardioprotection by poloxamer 188 is mediated through increased endothelial nitric oxide production.
Gaoxian Chen, Hunter F Douglas, Zhu Li, William J Cleveland, Claudius Balzer, Detlef Obal

Sci Rep· April 2025

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Cardioprotection by Poloxamer 188 is Mediated through Increased Endothelial Nitric Oxide Production.
Gaoxian Chen, Hunter F Douglas, Zhu Li, William J Cleveland, Claudius Balzer, Detlef Obal

bioRxiv· May 2024

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Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension.
Gaoxian Chen, Lorena Orozco, Sophia Parmisano, James W S Jahng, Carlos D Vera, Detlef Obal

Stem Cell Res· October 2023

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Detecting and measuring of GPCR signaling - comparison of human induced pluripotent stem cells and immortal cell lines.
Gaoxian Chen, Detlef Obal

Front Endocrinol (Lausanne)· June 2023

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Nasopharyngeal Ventilation Compared to Facemask Ventilation: A Prospective, Randomized, Crossover Trial in Two Different Elective Cohorts.
Rainer Lenhardt, Ozan Akca, Detlef Obal, Jerrad Businger, Elisabeth Cooke

Cureus· May 2023

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Elucidating effects of environmental exposure using human-induced pluripotent stem cell disease modeling.
Mark Chandy, Detlef Obal, Joseph C Wu

EMBO Mol Med· November 2022

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Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart.
Keqiang Yan, Zhanlong Mei, Jingjing Zhao, Md Aminul Islam Prodhan, Detlef Obal

J Am Heart Assoc· July 2022

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The obesity paradox: does it exist in the perioperative period?
Detlef Obal, Anupama Wadhwa

Int Anesthesiol Clin· February 2021

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Perioperative analgesic administration during the 2018 parenteral opioid shortage in the United States - A retrospective analysis.
Richard K Kim, Zijun Gao, Trevor Hastie, Detlef Obal

J Clin Anesth· November 2020

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Induced pluripotent stem cells as a platform to understand patient-specific responses to opioids and anaesthetics.
Detlef Obal, Joseph C Wu

Br J Pharmacol· October 2020

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A Guide to Understanding "State-of-the-Art" Basic Research Techniques in Anesthesiology.
Detlef Obal, Shaogen Wu, Andrew McKinstry-Wu, Vivianne L Tawfik

Anesth Analg· August 2020

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Cardiospecific Overexpression of ATPGD1 (Carnosine Synthase) Increases Histidine Dipeptide Levels and Prevents Myocardial Ischemia Reperfusion Injury.
Jingjing Zhao, Daniel J Conklin, Yiru Guo, Xiang Zhang, Detlef Obal

J Am Heart Assoc· June 2020

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TRPA1 channel contributes to myocardial ischemia-reperfusion injury.
Daniel J Conklin, Yiru Guo, Matthew A Nystoriak, Ganapathy Jagatheesan, Detlef Obal

Am J Physiol Heart Circ Physiol· April 2019

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Red Cell Storage Duration Does Not Affect Outcome after Massive Blood Transfusion in Trauma and Nontrauma Patients: A Retrospective Analysis of 305 Patients.
Alexander Bautista, Theodore B Wright, Janice Meany, Sunitha K Kandadai, Benjamin Brown, Detlef Obal

Biomed Res Int· March 2018

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Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.
Andrew A Gibb, Paul N Epstein, Shizuka Uchida, Yuting Zheng, Lindsey A McNally, Detlef Obal

Circulation· November 2017

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Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.
Daniel J Conklin, Yiru Guo, Ganapathy Jagatheesan, Peter J Kilfoil, Petra Haberzettl, Detlef Obal

Circ Res· August 2015

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Perioperative doses of ondansetron or dolasetron do not lengthen the QT interval.
Detlef Obal, Dongsheng Yang, Daniel I Sessler

Mayo Clin Proc· January 2014

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Cardiac myocyte-specific transgenic ecSOD targets mitochondria to protect against Ca(2+) induced permeability transition.
Jianzhu Luo, Detlef Obal, Neviana Dimova, Xian-Liang Tang, Gregg Rokosh

Front Physiol· November 2013

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Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion.
Detlef Obal, Shujing Dai, Rachel Keith, Neviana Dimova, Justin Kingery

Basic Res Cardiol· November 2012

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Ultrasound guidance for deep peripheral nerve blocks: a brief review.
Anupama Wadhwa, Sunitha Kanchi Kandadai, Sujittra Tongpresert, Detlef Obal, Ralf Erich Gebhard

Anesthesiol Res Pract· November 2011

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The effect of aminophylline on loss of consciousness, bispectral index, propofol requirement, and minimum alveolar concentration of desflurane in volunteers.
Alparslan Turan, Yusuke Kasuya, Raghavendra Govinda, Detlef Obal, Stefan Rauch

Anesth Analg· February 2010

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Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition.
Matthew B West, Gregg Rokosh, Detlef Obal, Murugesan Velayutham, Yu-Ting Xuan

Circulation· November 2008

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