Publications by authors named "Dev Karan"

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Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review.
Mohammad Amir Mishan, Yeun-Mun Choo, Jeffery Winkler, Mark T Hamann, Dev Karan

Eur J Pharmacol· March 2025

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Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8-DNA interactions and effectively inhibits prostate tumor growth in mice.
Dev Karan, Seema Dubey, Sumedha Gunewardena, Kenneth A Iczkowski, Manohar Singh

Mol Oncol· August 2024

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Targeting sine oculis homeoprotein 1 (SIX1): A review of oncogenic roles and potential natural product therapeutics.
Zhiwei Bian, Menny M Benjamin, Lucas Bialousow, Yintai Tian, G Aaron Hobbs, Dev Karan

Heliyon· June 2024

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Reply to "Contextualizing racial associations in prostate cancer to expose structural causes".
Dev Karan, Jo Wick, Seema Dubey, Chandan Kumar-Sinha, Javed Siddiqui

Cancer· February 2024

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Racial differences in serum chemokines in prostate cancer patients.
Dev Karan, Jo Wick, Seema Dubey, Chandan Kumar-Sinha, Javed Siddiqui

Cancer· December 2023

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DNA Methyltransferase 1 Targeting Using Guadecitabine Inhibits Prostate Cancer Growth by an Apoptosis-Independent Pathway.
Dev Karan, Manohar Singh, Seema Dubey, Peter J Van Veldhuizen, Yogen Saunthararajah

Cancers (Basel)· May 2023

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A Perspective on Modulating Antitumor Immunity in Targeting Prostate Cancer.
Seema Dubey, Manohar Singh, Ariel Nelson, Dev Karan

J Immunol Res· January 2022

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CCL23 in Balancing the Act of Endoplasmic Reticulum Stress and Antitumor Immunity in Hepatocellular Carcinoma.
Dev Karan

Front Oncol· October 2021

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RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study.
Alejandro M S Mayer, Mary L Hall, Joseph Lach, Jonathan Clifford, Kevin Chandrasena, Dev Karan

Mar Drugs· September 2021

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Circulatory MIC-1 as a Determinant of Prostate Cancer Racial Disparity.
Dev Karan, Jo Wick, Seema Dubey, Ossama Tawfik, Peter Van Veldhuizen

Cancers (Basel)· October 2020

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The Marine Natural Product Manzamine A Inhibits Cervical Cancer by Targeting the SIX1 Protein.
Dev Karan, Seema Dubey, Lucia Pirisi, Alexis Nagel, Ivett Pina

J Nat Prod· February 2020

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Inflammasomes: Emerging Central Players in Cancer Immunology and Immunotherapy.
Dev Karan

Front Immunol· November 2019

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Withaferin A Associated Differential Regulation of Inflammatory Cytokines.
Seema Dubey, Hyunho Yoon, Mark Steven Cohen, Prakash Nagarkatti, Mitzi Nagarkatti, Dev Karan

Front Immunol· April 2019

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Formulation of the bivalent prostate cancer vaccine with surgifoam elicits antigen-specific effector T cells in PSA-transgenic mice.
Dev Karan

Vaccine· October 2017

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Expression analysis of inflammasome sensors and implication of NLRP12 inflammasome in prostate cancer.
Dev Karan, Ossama Tawfik, Seema Dubey

Sci Rep· June 2017

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From Inflammation to Prostate Cancer: The Role of Inflammasomes.
Dev Karan, Seema Dubey

Adv Urol· July 2016

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Prostate immunotherapy: should all guns be aimed at the prostate-specific antigen?
Dev Karan

Immunotherapy· September 2013

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Combination immunotherapy with prostate GVAX and ipilimumab: safety and toxicity.
Dev Karan, Peter Van Veldhuizen

Immunotherapy· June 2012

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Cancer immunotherapy: a paradigm shift for prostate cancer treatment.
Dev Karan, Jeffrey M Holzbeierlein, Peter Van Veldhuizen, J Brantley Thrasher

Nat Rev Urol· May 2012

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Inflammation-associated regulation of the macrophage inhibitory cytokine (MIC-1) gene in prostate cancer.
Seema Dubey, Peter Vanveldhuizen, Jeffrey Holzbeierlein, Ossama Tawfik, J Brantley Thrasher, Dev Karan

Oncol Lett· May 2012

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Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice.
Dev Karan, Seema Dubey, Peter Van Veldhuizen, Jeffrey M Holzbeierlein, Ossama Tawfik

Immunotherapy· June 2011

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Aqueous extract of Rhodiola imbricata rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro.
Kamla P Mishra, Lilly Ganju, Sudipta Chanda, Dev Karan, Ramesh C Sawhney

Immunobiology· October 2009

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CpG oligonucleotide as an adjuvant for the treatment of prostate cancer.
David M Lubaroff, Dev Karan

Adv Drug Deliv Rev· March 2009

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Macrophage inhibitory cytokine-1: possible bridge molecule of inflammation and prostate cancer.
Dev Karan, Jeffrey Holzbeierlein, J Brantley Thrasher

Cancer Res· January 2009

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Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine.
Dev Karan, Arthur M Krieg, David M Lubaroff

Int J Cancer· October 2007

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