Publications by authors named "Devan V Mehrotra"

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Assessing Benefit in Patients With Heart Failure and Reduced Ejection Fraction: Analysis of the VICTORIA Trial Using Novel Prognostic Risk Stratification.
Christopher M O'Connor, Sarah Rathwell, Devan V Mehrotra, Stefano Corda, Ciaran J McMULLAN

J Card Fail· August 2025

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Is inadequate risk stratification diluting hazard ratio estimates in randomized clinical trials?
Devan V Mehrotra, Rachel Marceau West

Clin Trials· October 2024

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Analysis of composite time-to-event endpoints in cardiovascular outcome trials.
Rachel Marceau West, Gregory Golm, Devan V Mehrotra

Clin Trials· October 2024

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Multi-trait analysis of gene-by-environment interactions in large-scale genetic studies.
Lan Luo, Devan V Mehrotra, Judong Shen, Zheng-Zheng Tang

Biostatistics· April 2024

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Calculation of Phase 2 dose-finding study sample size for reliable Phase 3 dose selection.
Fang Liu, Qing Zhao, Anthony J Rodgers, Devan V Mehrotra

Pharm Stat· November 2023

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Applying polygenic risk score methods to pharmacogenomics GWAS: challenges and opportunities.
Song Zhai, Devan V Mehrotra, Judong Shen

Brief Bioinform· November 2023

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Statistical assessment of biomarker replicability using MAJAR method.
Yuhan Xie, Song Zhai, Wei Jiang, Hongyu Zhao, Devan V Mehrotra

Stat Methods Med Res· October 2023

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Integrating multiple traits for improving polygenic risk prediction in disease and pharmacogenomics GWAS.
Song Zhai, Bin Guo, Baolin Wu, Devan V Mehrotra, Judong Shen

Brief Bioinform· July 2023

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A fast and powerful linear mixed model approach for genotype-environment interaction tests in large-scale GWAS.
Wujuan Zhong, Aparna Chhibber, Lan Luo, Devan V Mehrotra, Judong Shen

Brief Bioinform· January 2023

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AWOT and CWOT for genotype and genotype-by-treatment interaction joint analysis in pharmacogenetics GWAS.
Hong Zhang, Devan V Mehrotra, Judong Shen

Bioinformatics· January 2023

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CAPITAL: Optimal subgroup identification via constrained policy tree search.
Hengrui Cai, Wenbin Lu, Rachel Marceau West, Devan V Mehrotra, Lingkang Huang

Stat Med· September 2022

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Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods.
Song Zhai, Hong Zhang, Devan V Mehrotra, Judong Shen

Nat Commun· September 2022

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A statistical perspective on baseline adjustment in pharmacogenomic genome-wide association studies of quantitative change.
Hong Zhang, Aparna Chhibber, Peter M Shaw, Devan V Mehrotra, Judong Shen

NPJ Genom Med· June 2022

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GWAS of longitudinal trajectories at biobank scale.
Seyoon Ko, Christopher A German, Aubrey Jensen, Judong Shen, Anran Wang, Devan V Mehrotra

Am J Hum Genet· March 2022

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Germline HLA landscape does not predict efficacy of pembrolizumab monotherapy across solid tumor types.
Aparna Chhibber, Lingkang Huang, Hong Zhang, Jialin Xu, Razvan Cristescu, Devan V Mehrotra

Immunity· January 2022

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VCSEL: PRIORITIZING SNP-SET BY PENALIZED VARIANCE COMPONENT SELECTION.
Juhyun Kim, Judong Shen, Anran Wang, Devan V Mehrotra, Seyoon Ko

Ann Appl Stat· December 2021

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CauchyCP: A powerful test under non-proportional hazards using Cauchy combination of change-point Cox regressions.
Hong Zhang, Qing Li, Devan V Mehrotra, Judong Shen

Stat Methods Med Res· November 2021

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Evaluating the Efficacy of Coronavirus Disease 2019 Vaccines.
Dan-Yu Lin, Donglin Zeng, Devan V Mehrotra, Lawrence Corey, Peter B Gilbert

Clin Infect Dis· October 2021

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A Deferred-Vaccination Design to Assess Durability of COVID-19 Vaccine Effect After the Placebo Group Is Vaccinated.
Dean Follmann, Jonathan Fintzi, Michael P Fay, Holly E Janes, Lindsey R Baden, Devan V Mehrotra

Ann Intern Med· August 2021

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Survival analysis using a 5-step stratified testing and amalgamation routine (5-STAR) in randomized clinical trials.
Devan V Mehrotra, Rachel Marceau West

Stat Med· August 2021

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Principal stratum strategy: Potential role in drug development.
Björn Bornkamp, Kaspar Rufibach, Jianchang Lin, Yi Liu, Devan V Mehrotra

Pharm Stat· July 2021

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Clinical Endpoints for Evaluating Efficacy in COVID-19 Vaccine Trials.
Devan V Mehrotra, Holly E Janes, Thomas R Fleming, Paula W Annunziato, Kathleen M Neuzil

Ann Intern Med· February 2021

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Survival analysis using a 5-step stratified testing and amalgamation routine (5-STAR) in randomized clinical trials.
Devan V Mehrotra, Rachel Marceau West

Stat Med· December 2020

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Assessing Durability of Vaccine Effect Following Blinded Crossover in COVID-19 Vaccine Efficacy Trials.
Dean Follmann, Jonathan Fintzi, Michael P Fay, Holly E Janes, Lindsey Baden, Devan V Mehrotra

medRxiv· December 2020

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Multi-trait analysis of rare-variant association summary statistics using MTAR.
Lan Luo, Judong Shen, Hong Zhang, Aparna Chhibber, Devan V Mehrotra

Nat Commun· June 2020

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