Publications by authors named "Devram S Ghorpade"

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PPARγ mediated enhanced lipid biogenesis fuels growth in a drug-tolerant hepatocyte environment.
Binayak Sarkar, Jyotsna Singh, Mohit Yadav, Priya Sharma, Raman Deep Sharma, Devram S Ghorpade

Elife· December 2025

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Development and Validation of AAV-Mediated Liver, Liver-VAT, and Liver-Brain SORT and Therapeutic Regulation of FASN in Hepatic De Novo Lipogenesis.
Ratulananda Bhadury, Mohammad Athar, Pooja Mishra, Chayanika Gogoi, Shubham Sharma, Devram S Ghorpade

Cells· March 2025

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Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.
Lale Ozcan, Devram S Ghorpade, Ze Zheng, Jane Cristina de Souza, Ke Chen

Cell Rep· June 2022

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Targeting Soluble DPP-4 for Insulin Resistance: Origin Matters.
Lale Ozcan, Devram S Ghorpade, Ira Tabas

J Clin Endocrinol Metab· March 2021

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Correction: AcPIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators.
Praveen Prakhar, Sahana Holla, Devram Sampat Ghorpade, Martine Gilleron, Germain Puzo

J Biol Chem· December 2019

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Withdrawal: Cooperative regulation of NOTCH1 protein-phosphatidylinositol 3-kinase (PI3K) signaling by NOD1, NOD2, and TLR2 receptors renders enhanced refractoriness to transforming growth factor-β (TGF-β)- or cytotoxic T-lymphocyte antigen 4 (CTLA-4)-mediated impairment of human dendritic cell maturation.
Devram Sampat Ghorpade, Srini V Kaveri, Jagadeesh Bayry, Kithiganahalli Narayanaswamy Balaji

J Biol Chem· December 2019

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Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.
Devram S Ghorpade, Lale Ozcan, Ze Zheng, Sarah M Nicoloro, Yuefei Shen

Nature· March 2018

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Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity.
Manikandan Subramanian, Lale Ozcan, Devram Sampat Ghorpade, Anthony W Ferrante, Ira Tabas

PLoS One· June 2016

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Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.
Lale Ozcan, Devram S Ghorpade, Ze Zheng, Jane Cristina de Souza, Ke Chen

Cell Rep· June 2016

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Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.
Lale Ozcan, Xiaoming Xu, Shi-Xian Deng, Devram S Ghorpade, Tiffany Thomas

Diabetes· October 2015

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Ac2PIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators.
Praveen Prakhar, Sahana Holla, Devram Sampat Ghorpade, Martine Gilleron, Germain Puzo

J Biol Chem· October 2015

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Mycobacterium bovis BCG promotes tumor cell survival from tumor necrosis factor-α-induced apoptosis.
Sahana Holla, Devram Sampat Ghorpade, Vikas Singh, Kushagra Bansal, Kithiganahalli Narayanaswamy Balaji

Mol Cancer· September 2014

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NOD2-nitric oxide-responsive microRNA-146a activates Sonic hedgehog signaling to orchestrate inflammatory responses in murine model of inflammatory bowel disease.
Devram Sampat Ghorpade, Akhuri Yash Sinha, Sahana Holla, Vikas Singh, Kithiganahalli Narayanaswamy Balaji

J Biol Chem· November 2013

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Nitric oxide and KLF4 protein epigenetically modify class II transactivator to repress major histocompatibility complex II expression during Mycobacterium bovis bacillus Calmette-Guerin infection.
Devram Sampat Ghorpade, Sahana Holla, Akhauri Yash Sinha, Senthil Kumar Alagesan, Kithiganahalli Narayanaswamy Balaji

J Biol Chem· July 2013

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Sonic hedgehog-dependent induction of microRNA 31 and microRNA 150 regulates Mycobacterium bovis BCG-driven toll-like receptor 2 signaling.
Devram Sampat Ghorpade, Sahana Holla, Srini V Kaveri, Jagadeesh Bayry, Shripad A Patil

Mol Cell Biol· February 2013

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MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages.
Devram Sampat Ghorpade, Rebecca Leyland, Mariola Kurowska-Stolarska, Shripad A Patil, Kithiganahalli Narayanaswamy Balaji

Mol Cell Biol· June 2012

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Cooperative regulation of NOTCH1 protein-phosphatidylinositol 3-kinase (PI3K) signaling by NOD1, NOD2, and TLR2 receptors renders enhanced refractoriness to transforming growth factor-beta (TGF-beta)- or cytotoxic T-lymphocyte antigen 4 (CTLA-4)-mediated impairment of human dendritic cell maturation.
Devram Sampat Ghorpade, Srini V Kaveri, Jagadeesh Bayry, Kithiganahalli Narayanaswamy Balaji

J Biol Chem· September 2011

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Src homology 3-interacting domain of Rv1917c of Mycobacterium tuberculosis induces selective maturation of human dendritic cells by regulating PI3K-MAPK-NF-kappaB signaling and drives Th2 immune responses.
Kushagra Bansal, Akhauri Yash Sinha, Devram Sampat Ghorpade, Shambhuprasad Kotresh Togarsimalemath, Shripad A Patil

J Biol Chem· November 2010

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