Publications by authors named "Dhananjay Umrani"

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Design and synthesis of novel spirocyclic carboxylic acids as potent and orally bioavailable DGAT1 inhibitors and their biological evaluation.
Summon Koul, Suresh Kurhade, Sandeep Bhosale, Keshav Naik, Videsh Salunkhe, Dhananjay Umrani

Bioorg Med Chem Lett· April 2022

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Effect of parthenolide, an NLRP3 inflammasome inhibitor, on insulin resistance in high-fat diet-obese mice.
Pavan Kumar Chinta, Suhas Tambe, Dhananjay Umrani, Ajay Kumar Pal, Mukesh Nandave

Can J Physiol Pharmacol· March 2022

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First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug.
Vincenzo Teneggi, Veronica Novotny-Diermayr, Lay Hoon Lee, Maryam Yasin, Pauline Yeo, Dhananjay N Umrani

Clin Transl Sci· January 2020

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Discovery and pharmacological evaluation of indole derivatives as potent and selective RORγt inverse agonist for multiple autoimmune conditions.
Nadim S Shaikh, Jitesh P Iyer, Yogesh S Munot, Partha P Mukhopadhyay, Amol A Raje, Dhananjay Umrani

Bioorg Med Chem Lett· August 2019

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Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia.
Anil M Deshpande, Debnath Bhuniya, Siddhartha De, Bhavesh Dave, Vinod P Vyavahare, Dhananjay Umrani

Eur J Med Chem· June 2017

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Discovery and evaluation of 1H-pyrrolo[2,3-b]pyridine based selective and reversible small molecule BTK inhibitors for the treatment of rheumatoid arthritis.
Mahesh Thakkar, Debnath Bhuniya, Rahul Kaduskar, Tanaji Mengawade, Keshav Naik, Dhananjay Umrani

Bioorg Med Chem Lett· April 2017

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Discovery of a potent and selective small molecule hGPR91 antagonist.
Debnath Bhuniya, Dhananjay Umrani, Bhavesh Dave, Deepak Salunke, Gagan Kukreja

Bioorg Med Chem Lett· June 2011

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Effect of sarpogrelate on altered STZ-diabetes induced cardiovascular responses to 5-hydroxytryptamine in rats.
Dhananjay N Umrani, Dipali N Bodiwala, Ramesh K Goyal

Mol Cell Biochem· July 2003

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Effect of chronic treatment with losartan on streptozotocin-induced renal dysfunction.
B Murali, Dhananjay N Umrani, Ramesh K Goyal

Mol Cell Biochem· July 2003

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Fenoldopam treatment improves peripheral insulin sensitivity and renal function in STZ-induced type 2 diabetic rats.
Dhananjay N Umrani, Ramesh K Goyal

Clin Exp Hypertens· May 2003

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Increased renal angiotensin II AT1 receptor function in obese Zucker rat.
Misti Becker, Dhananjay Umrani, Mustafa F Lokhandwala, Tahir Hussain

Clin Exp Hypertens· January 2003

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Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats.
Dhananjay N Umrani, Anees A Banday, Tahir Hussain, Mustafa F Lokhandwala

Hypertension· December 2002

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Beneficial effects of fenoldopam treatment on renal function in streptozotocin-induced diabetic rats.
Dhananjay N Umrani, Ramesh K Goyal

Clin Exp Hypertens· April 2002

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