Publications by authors named "Dharmeshkumar Patel"

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Rapid visual detection of tick borne in Indian buffaloes using loop mediated isothermal amplification assay targeting major surface protein 5 gene.
Niranjan Kumar, Jayesh Babulal Solanki, Dharmeshkumar Chandrakantbhai Patel

J Parasit Dis· December 2025

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Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents.
Franck Amblard, Zhe Chen, Kalouna Kra, Dharmeshkumar Patel, Leda Bassit

J Med Chem· November 2025

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Discovery of broad-spectrum antivirals targeting viral proteases using in silico structural modeling and cellular analysis.
Dharmeshkumar Patel, Ramyani De, Niloufar Azadi, Sujin Lee, Savannah Shooter

Antiviral Res· September 2025

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Combating yellow fever virus with 7-deaza-7-fluoro-2'-C-methyladenosine.
Julia C LeCher, Vivian Vasconcelos Costa, Lauren N Rust, Leda C Bassit, Dharmeshkumar Patel

Antimicrob Agents Chemother· May 2025

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Loss of the aryl hydrocarbon receptor promotes cancer cell resistance to BRAFV600E targeted therapies.
Mourad Zerfaoui, Dharmeshkumar Patel, Yueqi Zhang, Raymond F Schinazi, Youssef Errami

Signal Transduct Target Ther· May 2025

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Sustained antiviral insulin signaling during West Nile virus infection results in viral mutations.
Aditya B Char, Chasity E Trammell, Stephen Fawcett, Manish Chauhan, Yared Debebe, Dharmeshkumar Patel

Front Cell Infect Microbiol· December 2024

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Exploring the relationship between flumethrin resistance and Anaplasma marginale infection in Rhipicephalus (Boophilus) microplus ticks of cattle.
Meghavi Vasantbhai Patel, Niranjan Kumar, Jayesh Babulal Solanki, Irsadullakhan Habibullakhan Kalyani, Dharmeshkumar Chandrakantbhai Patel

Trop Anim Health Prod· April 2024

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Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers.
Zixing Fan, Anna Pavlova, Matthew C Jenkins, Leda Bassit, Mohammad Salman, Dharmeshkumar Patel

ACS Infect Dis· April 2024

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Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections.
Selwyn J Hurwitz, Ramyani De, Julia C LeCher, Jessica A Downs-Bowen, Shu Ling Goh, Dharmeshkumar Patel

Viruses· April 2024

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Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.
Franck Amblard, Julia C LeCher, Ramyani De, Shaoman Zhou, Peng Liu, Dharmeshkumar Patel

Eur J Med Chem· March 2024

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Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs).
Franck Amblard, Zhe Chen, John Wiseman, Shaoman Zhou, Peng Liu, Dharmeshkumar Patel

Bioorg Chem· December 2023

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The premise of capsid assembly modulators towards eliminating HBV persistence.
Leda Bassit, Franck Amblard, Dharmeshkumar Patel, Nicolas Biteau, Zhe Chen

Expert Opin Drug Discov· November 2023

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HIV nucleoside reverse transcriptase inhibitors.
Franck Amblard, Dharmeshkumar Patel, Eleftherios Michailidis, Steven J Coats, Mahesh Kasthuri

Eur J Med Chem· October 2022

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Discovery of a 2'-Fluoro,2'-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice.
Julia C LeCher, Keivan Zandi, Vivian Vasconcelos Costa, Franck Amblard, Sijia Tao, Dharmeshkumar Patel

Microorganisms· October 2022

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Assessment of a Computational Approach to Predict Drug Resistance Mutations for HIV, HBV and SARS-CoV-2.
Dharmeshkumar Patel, Suzane K Ono, Leda Bassit, Kiran Verma, Franck Amblard

Molecules· August 2022

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An EvoDevo Study of Salmonid Visual Opsin Dynamics and Photopigment Spectral Sensitivity.
Mariann Eilertsen, Wayne Iwan Lee Davies, Dharmeshkumar Patel, Jonathan E Barnes, Rita Karlsen, Jagdish Suresh Patel

Front Neuroanat· July 2022

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In silico design of a novel nucleotide antiviral agent by free energy perturbation.
Dharmeshkumar Patel, Bryan D Cox, Mahesh Kasthuri, Seema Mengshetti, Leda Bassit

Chem Biol Drug Des· June 2022

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The best backbone for HIV prevention, treatment, and elimination: Emtricitabine+tenofovir.
Raymond F Schinazi, Dharmeshkumar Patel, Maryam Ehteshami

Antivir Ther· April 2022

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Paired Simulations and Experimental Investigations into the Calcium-Dependent Conformation of Albumin.
Dharmeshkumar Patel, Stephanie L Haag, Jagdish Suresh Patel, F Marty Ytreberg, Matthew T Bernards

J Chem Inf Model· March 2022

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The Mechanism of Action of Hepatitis B Virus Capsid Assembly Modulators Can Be Predicted from Binding to Early Assembly Intermediates.
Anna Pavlova, Leda Bassit, Bryan D Cox, Maksym Korablyov, Christophe Chipot, Dharmeshkumar Patel

J Med Chem· March 2022

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Contemporary Approaches to the Discovery and Development of Broad-Spectrum Natural Product Prototypes for the Control of Coronaviruses.
George S Hanna, Yeun-Mun Choo, Ryan Harbit, Heather Paeth, Sarah Wilde, Dharmeshkumar Patel

J Nat Prod· November 2021

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DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya.
Brandi K Torrevillas, Sarah M Garrison, Alexander J McKeeken, Dharmeshkumar Patel, James T Van Leuven

Front Cell Infect Microbiol· June 2021

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Implementing and Assessing an Alchemical Method for Calculating Protein-Protein Binding Free Energy.
Dharmeshkumar Patel, Jagdish Suresh Patel, F Marty Ytreberg

J Chem Theory Comput· April 2021

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Short-wavelength-sensitive 2 (Sws2) visual photopigment models combined with atomistic molecular simulations to predict spectral peaks of absorbance.
Dharmeshkumar Patel, Jonathan E Barnes, Wayne I L Davies, Deborah L Stenkamp, Jagdish Suresh Patel

PLoS Comput Biol· October 2020

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Modulation of Lymphocyte Potassium Channel K1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Seow Theng Ong, Saumya Bajaj, Mark R Tanner, Shih Chieh Chang, Bankala Krishnarjuna, Dharmeshkumar Patel

ACS Pharmacol Transl Sci· August 2020

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