Publications by authors named "Diane Merry"

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PROTACs therapeutically target the polyglutamine androgen receptor in spinal and bulbar muscular atrophy models.
Agamjot Sangotra, Satya L Reddy, Curtis J Kuo, Weiguo Xiang, Diane E Merry

Neurotherapeutics· October 2025

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Mutant androgen receptor induces neurite loss and senescence independently of ARE binding in a neuronal model of SBMA.
Jordyn Karliner, Yuhong Liu, Diane E Merry

Proc Natl Acad Sci U S A· July 2024

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Blocking the dimerization of polyglutamine-expanded androgen receptor protects cells from DHT-induced toxicity by increasing AR turnover.
Allison Lisberg, Yuhong Liu, Diane E Merry

J Biol Chem· May 2024

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Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy.
Danielle DeBartolo, Frederick J Arnold, Yuhong Liu, Elana Molotsky, Hsin-Yao Tang, Diane E Merry

JCI Insight· March 2024

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A phenotypically robust model of spinal and bulbar muscular atrophy in Drosophila.
Kristin Richardson, Medha Sengupta, Alyson Sujkowski, Kozeta Libohova, Autumn C Harris, Diane E Merry

J Neurosci Res· January 2024

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Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice.
David R Garcia Castro, Joseph R Mazuk, Erin M Heine, Daniel Simpson, R Seth Pinches, Diane E Merry

iScience· August 2023

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Differentiating PC12 cells to evaluate neurite densities through live-cell imaging.
Jordyn Karliner, Diane E Merry

STAR Protoc· March 2023

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The role of ubiquitination in spinal and bulbar muscular atrophy.
Medha Sengupta, Anna Pluciennik, Diane E Merry

Front Mol Neurosci· October 2022

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Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy.
Elana Molotsky, Yuhong Liu, Andrew P Lieberman, Diane E Merry

Acta Neuropathol Commun· July 2022

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Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.
Anna Pluciennik, Yuhong Liu, Elana Molotsky, Gregory B Marsh, Bedri Ranxhi, Diane E Merry

J Clin Invest· January 2021

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Molecular Mechanisms and Therapeutics for SBMA/Kennedy's Disease.
Frederick J Arnold, Diane E Merry

Neurotherapeutics· October 2019

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Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy.
Frederick J Arnold, Anna Pluciennik, Diane E Merry

Sci Rep· January 2019

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Fluorescence Imaging of Huntingtin mRNA Knockdown.
Eunseon Oh, Yuhong Liu, Mahesh V Sonar, Diane E Merry, Eric Wickstrom

Bioconjug Chem· April 2018

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The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms.
Jill M Yersak, Heather L Montie, Erica S Chevalier-Larsen, Yuhong Liu, Lan Huang, Diane E Merry

Front Mol Neurosci· May 2017

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The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex.
Laura C Bott, Florian A Salomons, Dragan Maric, Yuhong Liu, Diane Merry

Sci Rep· June 2016

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Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy.
Tamar R Berger, Heather L Montie, Pranav Jain, Justin Legleiter, Diane E Merry

Brain Res· December 2015

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Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA.
Lori Zboray, Anna Pluciennik, Dana Curtis, Yuhong Liu, Lisa D Berman-Booty, Diane E Merry

Cell Rep· December 2015

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Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis.
Erin M Heine, Tamar R Berger, Anna Pluciennik, Christopher R Orr, Lori Zboray, Diane E Merry

J Biol Chem· May 2015

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Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.
David T Hoang, Lei Gu, Zhiyong Liao, Feng Shen, Pooja G Talati, Diane E Merry

Mol Cancer Ther· March 2015

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Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
Jason P Chua, Satya L Reddy, Zhigang Yu, Elisa Giorgetti, Heather L Montie, Diane E Merry

J Clin Invest· February 2015

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Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.
Jason P Chua, Satya L Reddy, Diane E Merry, Hiroaki Adachi, Masahisa Katsuno

Hum Mol Genet· March 2014

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Cell biological approaches to investigate polyglutamine-expanded AR metabolism.
Lori J Cooper, Diane E Merry

Methods Mol Biol· December 2013

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Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Adrienne M Wang, Yoshinari Miyata, Susan Klinedinst, Hwei-Ming Peng, Jason P Chua, Diane E Merry

Nat Chem Biol· February 2013

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Attacking the flank: targeting new pathways in SBMA.
Diane E Merry

Nat Med· October 2012

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Guidelines for the use and interpretation of assays for monitoring autophagy.
Daniel J Klionsky, Fabio C Abdalla, Hagai Abeliovich, Robert T Abraham, Abraham Acevedo-Arozena, Diane E Merry

Autophagy· April 2012

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