Publications by authors named "Dianze Chen"

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Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD.
Dianze Chen, Song Li, Yanan Yang, Dandan Liu, Chunmei Yang

J Pharm Biomed Anal· December 2024

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IMM2520, a novel anti-CD47/PD-L1 bispecific antibody for cancer immune therapy.
Chunmei Yang, Song Li, Dianze Chen, Dandan Liu, Yanan Yang

Heliyon· November 2024

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Combining CD38 antibody with CD47 blockade is a promising strategy for treating hematologic malignancies expressing CD38.
Song Li, Dianze Chen, Yanan Yang, Huiqin Guo, Dandan Liu

Front Immunol· July 2024

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IMM47, a humanized monoclonal antibody that targets CD24, exhibits exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction and can be used as monotherapy or in combination with anti-PD1 antibodies for cancer immunotherapy.
Song Li, Dianze Chen, Huiqin Guo, Yanan Yang, Dandan Liu

Antib Ther· October 2023

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The novel high-affinity humanized antibody IMM40H targets CD70, eliminates tumors via Fc-mediated effector functions, and interrupts CD70/CD27 signaling.
Song Li, Dianze Chen, Huiqin Guo, Dandan Liu, Chunmei Yang

Front Oncol· October 2023

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IMM0306, a fusion protein of CD20 mAb with the CD47 binding domain of SIRPα, exerts excellent cancer killing efficacy by activating both macrophages and NK cells via blockade of CD47-SIRPα interaction and FcɣR engagement by simultaneously binding to CD47 and CD20 of B cells.
Jifeng Yu, Song Li, Dianze Chen, Dandan Liu, Huiqin Guo

Leukemia· March 2023

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SIRPα-Fc fusion protein IMM01 exhibits dual anti-tumor activities by targeting CD47/SIRPα signal pathway via blocking the "don't eat me" signal and activating the "eat me" signal.
Jifeng Yu, Song Li, Dianze Chen, Dandan Liu, Huiqin Guo

J Hematol Oncol· November 2022

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Crystal Structure of Human CD47 in Complex with Engineered SIRPα.D1(N80A).
Jifeng Yu, Song Li, Dianze Chen, Dandan Liu, Huiqin Guo

Molecules· August 2022

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