Publications by authors named "Dillon Gavlock"

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PNPLA3-I148M genetic variant rewires lipid metabolism to drive programmed cell death in human hepatocytes.
Rodrigo M Florentino, Olamide Animasahun, Nils Haep, Minal Nenwani, Kehinde Omoloja, Dillon C Gavlock

JCI Insight· December 2025

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Discovery and validation of small molecule stabilizers of mutant triose phosphate isomerase (TPI) as potential lead candidates for TPI deficiency.
Laura L Vollmer, Presley Roberts, Samantha L Eicher, Marta Wołosowicz, Priyal Patel, Dillon Gavlock

SLAS Discov· October 2025

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Human-induced pluripotent stem cell-based hepatic modeling of lipid metabolism-associated TM6SF2-E167K variant.
Lanuza A P Faccioli, Yiyue Sun, Olamide Animasahun, Takashi Motomura, Zhenghao Liu, Dillon C Gavlock

Hepatology· September 2025

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Validation of microphysiological systems for interpreting patient heterogeneity requires robust reproducibility analytics and experimental metadata.
Mark T Miedel, Mahboubeh Varmazyad, Mengying Xia, Maria Mori Brooks, Dillon C Gavlock

Cell Rep Methods· April 2025

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A metabolic dysfunction-associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system.
Julio Aleman, Ravikumar K, Connor Wiegand, Mark E Schurdak, Lawrence Vernetti, Dillon Gavlock

Commun Biol· October 2024

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Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy.
Mengying Xia, Mahboubeh Varmazyad, Iris Pla-Palacín, Dillon C Gavlock, Richard DeBiasio

Front Cell Dev Biol· September 2024

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Comparison of Wild-Type and High-risk PNPLA3 variants in a Human Biomimetic Liver Microphysiology System for Metabolic Dysfunction-associated Steatotic Liver Disease Precision Therapy.
Mengying Xia, Maboubeh Varmazyad, Iris Pla Palacin, Dillon C Gavlock, Richard Debiasio

bioRxiv· May 2024

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A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system.
Julio Aleman, K Ravikumar, Connor Wiegand, Mark E Schurdak, Lawrence Vernetti, Dillon Gavlock

bioRxiv· April 2024

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Modeling mechanisms underlying differential inflammatory responses to COVID-19 in type 2 diabetes using a patient-derived microphysiological organ-on-a-chip system.
Vinny Negi, Dillon Gavlock, Mark T Miedel, Jeong Kyung Lee, Tongying Shun

Lab Chip· October 2023

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Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
Manush Saydmohammed, Anupma Jha, Vineet Mahajan, Dillon Gavlock, Tong Ying Shun

Exp Biol Med (Maywood)· November 2021

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Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System.
Mark T Miedel, Dillon C Gavlock, Shanhang Jia, Albert Gough, D Lansing Taylor

Sci Rep· June 2019

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