Publications by authors named "Dima Sabbah"

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Molecular and System-Level Characterization of MMP12 Suppression in Lung Cancer: A Combined Bioinformatics and Molecular Approach.
Shriefa Almutairi, Rima Hajjo, Dima A Sabbah, Kamal Sweidan, Zainab Ahmed Rashid

Int J Mol Sci· December 2025

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Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis.
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Dima Sabbah

Adv Sci (Weinh)· October 2025

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Identification and Biological Validation of MMP-12 Inhibitors Guided by Pharmacophore-Based Virtual Screening and Docking Studies.
Shriefa Almutairi, Dima A Sabbah, Kamal Sweidan, Rima Hajjo, Sanaa K Bardaweel

ACS Omega· October 2025

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Exploring the anticancer potential of nitrated N-substituted-4-hydroxy-2-quinolone-3-carboxamides: synthesis, biological assessment, and computational analysis.
Reem A Islim, Nisreen S Hamadeh, Reema Abu Khalaf, Rima Hajjo, Sanaa K Bardaweel, Dima A Sabbah

BMC Chem· August 2025

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Exploring Carboxamide Derivatives as Promising Anticancer Agents: Design, In Vitro Evaluation, and Mechanistic Insights.
Manal M Al-Najdawi, Maysaa M Saleh, Dima A Sabbah, Rima Hajjo, Hiba Zalloum

Int J Mol Sci· June 2025

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An Overview of the Potential Use of Selective Serotonin Reuptake Inhibitors (SSRIs) in Cancer Treatment.
Sanaa K Bardaweel, Rima Hajjo, Osama H Abusara, Dima Sabbah, Dima Hattab

Curr Cancer Drug Targets· June 2025

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Computational Insights into the Polypharmacological Landscape of BCR-ABL Inhibitors: Emphasis on Imatinib and Nilotinib.
Rima Hajjo, Dima A Sabbah, Raghad Alhaded, Aye Alquabe'h, Sanaa K Bardaweel

Pharmaceuticals (Basel)· June 2025

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Synthesis, Characterization and Preliminary Screening of New N-Substituted -8-Methyl-4-Hydroxy-2-Quinolone -3-Carboxamides as Potential Anticancer Agents.
Dania Altaher, Hiba Zalloum, Kamal Sweidan, Dima A Sabbah, Husam AlSalamat

Curr Org Synth· May 2025

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Advancing the understanding and management of Mpox: insights into epidemiology, disease pathways, prevention, and therapeutic strategies.
Rima Hajjo, Osama H Abusara, Dima A Sabbah, Sanaa K Bardaweel

BMC Infect Dis· April 2025

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Targeting MAO-B with Small-Molecule Inhibitors: A Decade of Advances in Anticancer Research (2012-2024).
Iyman Alsaad, Diana M A Abdel Rahman, Ola Al-Tamimi, Shayma'a A Alhaj, Dima A Sabbah

Molecules· December 2024

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Polymeric Nanoparticles Potentiate the Anticancer Activity of Novel PI3Kα Inhibitors Against Triple-Negative Breast Cancer Cells.
Suhair Sunoqrot, Samah Abusulieh, Dima Sabbah

Biomedicines· November 2024

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Unveiling the Intricacies of Monoamine Oxidase-A (MAO-A) Inhibition in Colorectal Cancer: Computational Systems Biology, Expression Patterns, and the Anticancer Therapeutic Potential.
Sanaa K Bardaweel, Husam Al-Salamat, Rima Hajjo, Dima Sabbah, Shriefa Almutairi

ACS Omega· August 2024

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Synthesis, Molecular Modeling and Biological Evaluation of Novel Trifluoromethyl Benzamides as Promising CETP Inhibitors.
Reema Abu Khalaf, Amani Abusaad, Bara'a Al-Nawaiseh, Dima Sabbah, Ghadeer Albadawi

Curr Comput Aided Drug Des· May 2024

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Targeting the EGFR/RAS/RAF signaling pathway in anticancer research: a recent update on inhibitor design and clinical trials (2020-2023).
Rima Hajjo, Dima A Sabbah, Sanaa K Bardaweel, Haizhen A Zhong

Expert Opin Ther Pat· April 2024

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Targeting the PI3K/AKT signaling pathway in anticancer research: a recent update on inhibitor design and clinical trials (2020-2023).
Dima A Sabbah, Rima Hajjo, Sanaa K Bardaweel, Haizhen A Zhong

Expert Opin Ther Pat· March 2024

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A Critical Assessment of COVID-19 Genomic Vaccines.
Dima A Sabbah, Rima Hajjo, Suhair Sunoqrot

Curr Top Med Chem· November 2023

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A cross-sectional study confirms temporary post-COVID-19 vaccine menstrual irregularity and the associated physiological changes among vaccinated women in Jordan.
Ensaf Y Almomani, Rima Hajjo, Ahmad Qablan, Dima A Sabbah, Abass Al-Momany

Front Med (Lausanne)· October 2023

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Identifying a causal link between prolactin signaling pathways and COVID-19 vaccine-induced menstrual changes.
Rima Hajjo, Ensaf Momani, Dima A Sabbah, Nancy Baker, Alexander Tropsha

NPJ Vaccines· September 2023

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Trifluoromethylated Aryl Sulfonamides as Novel CETP Inhibitors: Synthesis, Induced Fit Docking, Pharmacophore Mapping and Subsequent Validation.
Reema Abu Khalaf, Hamza Al Shaiah, Dima Sabbah

Med Chem· March 2023

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Targeting Human Proteins for Antiviral Drug Discovery and Repurposing Efforts: A Focus on Protein Kinases.
Rima Hajjo, Dima A Sabbah, Osama H Abusara, Reham Kharmah, Sanaa Bardaweel

Viruses· February 2023

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A Review of the Recent Advances in Alzheimer's Disease Research and the Utilization of Network Biology Approaches for Prioritizing Diagnostics and Therapeutics.
Rima Hajjo, Dima A Sabbah, Osama H Abusara, Abdel Qader Al Bawab

Diagnostics (Basel)· November 2022

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Vitamin E TPGS-Poloxamer Nanoparticles Entrapping a Novel PI3Kα Inhibitor Potentiate Its Activity against Breast Cancer Cell Lines.
Suhair Sunoqrot, Sundos Aliyeh, Samah Abusulieh, Dima Sabbah

Pharmaceutics· September 2022

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Unlocking the Potential of the Human Microbiome for Identifying Disease Diagnostic Biomarkers.
Rima Hajjo, Dima A Sabbah, Abdel Qader Al Bawab

Diagnostics (Basel)· July 2022

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Analyzing the Systems Biology Effects of COVID-19 mRNA Vaccines to Assess Their Safety and Putative Side Effects.
Rima Hajjo, Dima A Sabbah, Alexander Tropsha

Pathogens· June 2022

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Design, Synthesis, and Biological Evaluation of Novel MAO-A Inhibitors Targeting Lung Cancer.
Sanaa Bardaweel, Reem Aljanabi, Dima Sabbah, Kamal Sweidan

Molecules· April 2022

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