Publications by authors named "Dimitris Kletsas"

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Senescent Fibroblasts Drive Melanoma Progression Through GCP-2 Induced CREB Phosphorylation Enhancing Glycolysis.
Abhijit Basu, Vida Farsam, Karmveer Singh, Diana Crisan, Nicolai Treiber, Dimitris Kletsas

Aging Cell· December 2025

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Immune cell senescence drives responsiveness to immunotherapy in melanoma.
Pavlos Pantelis, Dimitrios Christos Tremoulis, Konstantinos Evangelou, Panagiotis Bakouros, Sophia Magkouta, Dimitris Kletsas

Mol Cancer· December 2025

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The regenerative potential of young versus senescent rabbit adipose-derived mesenchymal stem cells and their impact on the treatment of intervertebral disc degeneration.
Eleni Mavrogonatou, Agori-Maria Korompilia, Evangeli Lampri, Vasiliki S Kavvadia, Dimitrios Kosmas, Dimitris Kletsas

Spine J· December 2025

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The dark side of the light (UVA): melanoma microenvironment and cell survival strategies.
Abhijit Basu, Peters Thorsten, Björn Schumacher, Dimitris Kletsas, Karin Scharffetter-Kochanek

Cell Death Discov· October 2025

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The effect of copper on the antifungal activity of polyethyleneimines against quiescent conidia and germlings of Aspergillus nidulans.
Dimitris Tsiourvas, Zili Sideratou, Eleni Mavrogonatou, Dimitris Kletsas, Vicky Sophianopoulou

Sci Rep· July 2025

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Screening of a Plant Extract Library from the Greek Flora for Biological Activities Related to Anti-Aging Applications.
Harris Pratsinis, Despoina D Gianniou, Gabriela Belén Lemus Ringele, Adamantia Agalou, Asimina Fotopoulou, Dimitris Kletsas

Antioxidants (Basel)· July 2025

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Molecular and Environmental Modulators of Aging: Interplay Between Inflammation, Epigenetics, and RNA Stability.
Konstantina Dragoumani, Dimitris Kletsas, George P Chrousos, Dimitrios Vlachakis, Nikolaos A A Balatsos

Genes (Basel)· July 2025

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Accumulation Kinetics and Biological Action of Doxorubicin in Rabbit Intervertebral Discs.
Eleni Mavrogonatou, Anastasios Kouroumalis, Lubna Khaldi, Christophoros Christophoridis, Dimitris Kletsas

Int J Mol Sci· July 2025

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Natural Product-Derived Senotherapeutics: Extraction and Biological Evaluation Techniques.
Harris Pratsinis, Eleni Mavrogonatou, Sevasti-Kiriaki Zervou, Theodoros Triantis, Anastasia Hiskia, Dimitris Kletsas

Methods Mol Biol· May 2025

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Copper-Chelated Hyperbranched Polyethyleneimines with Antifungal Activity against quiescent conidia and germlings of the opportunistic fungal pathogen Aspergillus nidulans.
Dimitris Tsiourvas, Zili Sideratou, Eleni Mavrogonatou, Dimitris Kletsas, Vicky Sophianopoulou

Res Sq· May 2025

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A subset of human dermal fibroblasts overexpressing Cockayne syndrome group B protein resist UVB radiation-mediated premature senescence.
Asimina Fotopoulou, Maria T Angelopoulou, Harris Pratsinis, Eleni Mavrogonatou, Dimitris Kletsas

Aging Cell· March 2025

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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles.
Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis

J Exp Clin Cancer Res· February 2025

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Stimulation of IRES-Dependent Translation by Rocaglamide A Increases the Replication and Virulence of Cricket Paralysis Virus in Lepidopteran Insect Cells.
Dulce Santos, Vasiliki-Maria Christopoulou, Clauvis Nji Tizi Taning, Socratis Avgeris, Adamantia Papadopoulou, Dimitris Kletsas

Arch Insect Biochem Physiol· January 2025

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Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement.
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen

Periodontol 2000· August 2024

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Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy.
Andriani Angelopoulou, Giorgos Theocharous, Dimitrios Valakos, Aikaterini Polyzou, Sophia Magkouta, Dimitris Kletsas

Mol Cancer· July 2024

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New long-standing metabolites of 17α-methyltestosterone are detected in HepG2 cell in vitro metabolic model and in human urine.
Yiannis S Angelis, Panagiotis Sakellariou, Argyro G Fragkaki, Sophia Karnava, Olga Goula, Dimitris Kletsas

Drug Test Anal· June 2024

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Biological Activities of Citrus-Derived Extracellular Vesicles on Human Cells: The Role of Preservation.
Theodora Karamanidou, Konstantinos Krommydas, Maria Karanikou, Dimitrios Tsamos, Konstantinos Michalakis, Dimitris Kletsas

Curr Issues Mol Biol· June 2024

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Design and Synthesis of Novel Antioxidant 2-Substituted-5,7,8-Trimethyl-1,4-Benzoxazine Hybrids: Effects on Young and Senescent Fibroblasts.
Theano Fotopoulou, Adamantia Papadopoulou, Andromachi Tzani, Michail Mamais, Eleni Mavrogonatou, Dimitris Kletsas

Antioxidants (Basel)· June 2024

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Plant-Derived Senotherapeutics for the Prevention and Treatment of Intervertebral Disc Degeneration and Aging.
Eleni Mavrogonatou, Dimitris Kletsas

Metabolites· February 2024

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Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles.
Nikolaos Lougiakis, Nikolaos Sakalis, Maria Georgiou, Panagiotis Marakos, Nicole Pouli, Dimitris Kletsas

Eur J Med Chem· December 2023

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Senescence-associated alterations in the extracellular matrix: deciphering their role in the regulation of cellular function.
Eleni Mavrogonatou, Adamantia Papadopoulou, Harris Pratsinis, Dimitris Kletsas

Am J Physiol Cell Physiol· September 2023

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A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer.
Ioanna Mourkioti, Aikaterini Polyzou, Dimitris Veroutis, George Theocharous, Nefeli Lagopati, Dimitris Kletsas

J Exp Clin Cancer Res· July 2023

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Biological Activities of Pod and Seed Extracts: A Comparative Analysis of Two Cretan Cultivars.
Dafni-Alexandra Kavvoura, Michalis K Stefanakis, Dimitris Kletsas, Haralambos E Katerinopoulos, Harris Pratsinis

Int J Mol Sci· July 2023

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A Novel Experimental Rat Model for the Assessment of Myocardial Ischemia Based on Single Photon Emission Computed Tomography.
Antonella Koutela, George Loudos, Maritina Rouchota, Dimitris Kletsas, Andreas Karameris

In Vivo· March 2023

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Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations.
Katarzyna Malgorzata Kwiatkowska, Eleni Mavrogonatou, Adamantia Papadopoulou, Claudia Sala, Luciano Calzari, Dimitris Kletsas

Cells· March 2023

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