Publications by authors named "Dirk Chelius"

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Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction.
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Dirk Chelius

MAbs· December 2022

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Ion-pair reversed-phase high performance liquid chromatography method for the quantification of isoaspartic acid in a monoclonal antibody.
Wolfram Kern, Robin Mende, Blandine Denefeld, Mirko Sackewitz, Dirk Chelius

J Chromatogr B Analyt Technol Biomed Life Sci· April 2014

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Identification of methionine sulfoxide diastereomers in immunoglobulin gamma antibodies using methionine sulfoxide reductase enzymes.
Hui K Khor, Michael E Jacoby, Thomas C Squier, Grace C Chu, Dirk Chelius

MAbs· December 2010

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Structural and functional characterization of the trifunctional antibody catumaxomab.
Dirk Chelius, Peter Ruf, Patrick Gruber, Matthias Plöscher, Reinhard Liedtke

MAbs· December 2010

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Identification and characterization of oxidation and deamidation sites in monoclonal rat/mouse hybrid antibodies.
Vera Timm, Patrick Gruber, Michael Wasiliu, Horst Lindhofer, Dirk Chelius

J Chromatogr B Analyt Technol Biomed Life Sci· March 2010

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Label-free global serum proteomic profiling reveals novel celecoxib-modulated proteins in familial adenomatous polyposis patients.
Naheed Fatima, Dirk Chelius, Brian T Luke, Ming Yi, Terry Zhang

Cancer Genomics Proteomics· June 2009

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Automated tryptic digestion procedure for HPLC/MS/MS peptide mapping of immunoglobulin gamma antibodies in pharmaceutics.
Dirk Chelius, Gang Xiao, Andrew C Nichols, Alona Vizel, Bing He

J Pharm Biomed Anal· June 2008

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Isomerization of a single aspartyl residue of anti-epidermal growth factor receptor immunoglobulin gamma2 antibody highlights the role avidity plays in antibody activity.
Douglas S Rehder, Dirk Chelius, Arnold McAuley, Thomas M Dillon, Gang Xiao

Biochemistry· February 2008

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Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures.
Grace C Chu, Dirk Chelius, Gang Xiao, Hui K Khor, Sururat Coulibaly

Pharm Res· June 2007

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18O labeling method for identification and quantification of succinimide in proteins.
Gang Xiao, Pavel V Bondarenko, Jaby Jacob, Grace C Chu, Dirk Chelius

Anal Chem· April 2007

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Insight into the virulence of Rickettsia prowazekii by proteomic analysis and comparison with an avirulent strain.
Chien-Chung Chao, Dirk Chelius, Terry Zhang, Elissa Mutumanje, Wei-Mei Ching

Biochim Biophys Acta· March 2007

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Reversed-phase liquid chromatography in-line with negative ionization electrospray mass spectrometry for the characterization of the disulfide-linkages of an immunoglobulin gamma antibody.
Dirk Chelius, Mary E Huff Wimer, Pavel V Bondarenko

J Am Soc Mass Spectrom· November 2006

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Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies.
Dirk Chelius, Kay Jing, Alexis Lueras, Douglas S Rehder, Thomas M Dillon

Anal Chem· April 2006

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Identification and characterization of deamidation sites in the conserved regions of human immunoglobulin gamma antibodies.
Dirk Chelius, Douglas S Rehder, Pavel V Bondarenko

Anal Chem· September 2005

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Characterization of protein glycosylation using chip-based infusion nanoelectrospray linear ion trap tandem mass spectrometry.
Sheng Zhang, Dirk Chelius

J Biomol Tech· June 2004

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Proteome analysis of Madrid E strain of Rickettsia prowazekii.
Chien-Chung Chao, Dirk Chelius, Terry Zhang, Lindsey Daggle, Wei-Mei Ching

Proteomics· May 2004

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Global protein identification and quantification technology using two-dimensional liquid chromatography nanospray mass spectrometry.
Dirk Chelius, Terry Zhang, Guanghui Wang, Rong-Fong Shen

Anal Chem· December 2003

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Capture of peptides with N-terminal serine and threonine: a sequence-specific chemical method for Peptide mixture simplification.
Dirk Chelius, Thomas A Shaler

Bioconjug Chem· July 2003

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Quantitative profiling of proteins in complex mixtures using liquid chromatography and mass spectrometry.
Dirk Chelius, Pavel V Bondarenko

J Proteome Res· June 2003

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Analysis of the adenovirus type 5 proteome by liquid chromatography and tandem mass spectrometry methods.
Dirk Chelius, Andreas F R Hühmer, Chia H Shieh, Elisabeth Lehmberg, Joseph A Traina

J Proteome Res· April 2003

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Identification and relative quantitation of protein mixtures by enzymatic digestion followed by capillary reversed-phase liquid chromatography-tandem mass spectrometry.
Pavel V Bondarenko, Dirk Chelius, Thomas A Shaler

Anal Chem· September 2002

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Identification of N-linked oligosaccharides of rat insulin-like growth factor binding protein-4.
Dirk Chelius, Shiaw-Lin Wu, Pavel V Bondarenko

Growth Horm IGF Res· June 2002

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