Publications by authors named "Dirk Sieger"

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Enabling mechanistic studies of EVs in vivo: a protocol for isolation and cell-specific labelling in larval zebrafish.
Ezgi Kiyga, Katy Reid, Guillaume van Niel, Julie Mazzolini, Dirk Sieger

Cell Commun Signal· October 2025

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Calciumnetexplorer: an R package for network analysis of calcium imaging data.
Simone Lenci, Dirk Sieger

BMC Bioinformatics· August 2025

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Targeting glioblastoma through nano- and micro-particle-mediated immune modulation.
Ellen Poot, Ander Maguregui, Valerie G Brunton, Dirk Sieger, Alison N Hulme

Bioorg Med Chem· October 2022

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Zebrafish as a model organism for neurodegenerative disease.
Kelda Chia, Anna Klingseisen, Dirk Sieger, Josef Priller

Front Mol Neurosci· October 2022

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Wasl is crucial to maintain microglial core activities during glioblastoma initiation stages.
Julie Mazzolini, Sigrid Le Clerc, Gregoire Morisse, Cédric Coulonges, Jean-François Zagury, Dirk Sieger

Glia· June 2022

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Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.
M Carmen Ortega-Liebana, Nicola J Porter, Catherine Adam, Teresa Valero, Lloyd Hamilton, Dirk Sieger

Angew Chem Int Ed Engl· January 2022

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GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis.
Hannah Larbalestier, Marcus Keatinge, Lisa Watson, Emma White, Siri Gowda, Dirk Sieger

J Neurosci· January 2022

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Truly-Biocompatible Gold Catalysis Enables Vivo-Orthogonal Intra-CNS Release of Anxiolytics.
M Carmen Ortega-Liebana, Nicola J Porter, Catherine Adam, Teresa Valero, Lloyd Hamilton, Dirk Sieger

Angew Chem Weinheim Bergstr Ger· January 2022

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Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo.
Sam Benson, Fabio de Moliner, Antonio Fernandez, Erkin Kuru, Nicholas L Asiimwe, Dirk Sieger

Nat Commun· April 2021

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Zebrafish In Vivo Models of Cancer and Metastasis.
Katy R Astell, Dirk Sieger

Cold Spring Harb Perspect Med· August 2020

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Gene expression profiling reveals a conserved microglia signature in larval zebrafish.
Julie Mazzolini, Sigrid Le Clerc, Gregoire Morisse, Cédric Coulonges, Laura E Kuil, Dirk Sieger

Glia· February 2020

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Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation.
Kelda Chia, Marcus Keatinge, Julie Mazzolini, Dirk Sieger

Elife· July 2019

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Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices.
Catherine Adam, Ana M Pérez-López, Lloyd Hamilton, Belén Rubio-Ruiz, Thomas L Bray, Dirk Sieger

Chemistry· November 2018

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Isolation and RNA Extraction of Neurons, Macrophages and Microglia from Larval Zebrafish Brains.
Julie Mazzolini, Kelda Chia, Dirk Sieger

J Vis Exp· April 2018

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Tumor initiating cells induce Cxcr4-mediated infiltration of pro-tumoral macrophages into the brain.
Kelda Chia, Julie Mazzolini, Marina Mione, Dirk Sieger

Elife· February 2018

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Complement as a regulator of adaptive immunity.
Justin Killick, Gregoire Morisse, Dirk Sieger, Anne L Astier

Semin Immunopathol· January 2018

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Gold-Triggered Uncaging Chemistry in Living Systems.
Ana M Pérez-López, Belén Rubio-Ruiz, Víctor Sebastián, Lloyd Hamilton, Catherine Adam, Dirk Sieger

Angew Chem Int Ed Engl· October 2017

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A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth.
Marie Mayrhofer, Victor Gourain, Markus Reischl, Pierre Affaticati, Arnim Jenett, Dirk Sieger

Dis Model Mech· January 2017

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A Zebrafish Live Imaging Model Reveals Differential Responses of Microglia Toward Glioblastoma Cells In Vivo.
Lloyd Hamilton, Katy R Astell, Gergana Velikova, Dirk Sieger

Zebrafish· December 2016

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Spinal motor neurons are regenerated after mechanical lesion and genetic ablation in larval zebrafish.
Jochen Ohnmacht, Yujie Yang, Gianna W Maurer, Antón Barreiro-Iglesias, Themistoklis M Tsarouchas, Dirk Sieger

Development· May 2016

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Carcinoma cells misuse the host tissue damage response to invade the brain.
Han-Ning Chuang, Denise van Rossum, Dirk Sieger, Laila Siam, Florian Klemm

Glia· August 2013

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Animal models for studying microglia: the first, the popular, and the new.
Dirk Sieger, Francesca Peri

Glia· January 2013

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Factor associated with neutral sphingomyelinase activity mediates navigational capacity of leukocytes responding to wounds and infection: live imaging studies in zebrafish larvae.
Alexandra Boecke, Dirk Sieger, Cristian Dan Neacsu, Hamid Kashkar, Martin Krönke

J Immunol· August 2012

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Long-range Ca2+ waves transmit brain-damage signals to microglia.
Dirk Sieger, Christian Moritz, Thomas Ziegenhals, Sergey Prykhozhij, Francesca Peri

Dev Cell· June 2012

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In vivo analysis of Ifn-γ1 and Ifn-γ2 signaling in zebrafish.
Dina Aggad, Cornelia Stein, Dirk Sieger, Martine Mazel, Pierre Boudinot

J Immunol· December 2010

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