Publications by authors named "Do-Wan Shim"

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Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis.
Do-Wan Shim, Jun-Cheol Eo, Saeyoung Kim, Inhwa Hwang, BoYoung Nam

Exp Mol Med· February 2024

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Intracellular NAD Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation.
Do-Wan Shim, Hyo-Joung Cho, Inhwa Hwang, Taek-Yeol Jung, Hyun-Seok Kim

Front Immunol· February 2022

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Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu.
Seunghwan Son, Sung-Hyun Yoon, Byeong Jun Chae, Inhwa Hwang, Do-Wan Shim

Front Immunol· January 2022

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Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation.
Seunghwan Son, Do-Wan Shim, Inhwa Hwang, Jong-Hwan Park, Je-Wook Yu

Front Immunol· September 2020

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Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner.
Eunji Gim, Do-Wan Shim, Inhwa Hwang, Ok Sarah Shin, Je-Wook Yu

Immune Netw· December 2019

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Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome.
Do-Wan Shim, Kwang-Ho Lee

Front Immunol· July 2019

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Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.
Kang-Hyuck Heo, Xiao Sun, Do-Wan Shim, Myong-Ki Kim, Sushruta Koppula

J Ethnopharmacol· March 2018

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Inhibitory Effect and Mechanism of Extract Inflammasome Activation.
Young-Kyu Kim, Sushruta Koppula, Do-Wan Shim, Eun-Jung In, Su-Bin Kwak

Evid Based Complement Alternat Med· January 2018

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BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.
Do-Wan Shim, Woo-Young Shin, Sang-Hyeun Yu, Byung-Hak Kim, Sang-Kyu Ye

Sci Rep· November 2017

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Protective effects of Cinnamomum cassia (Lamaceae) against gout and septic responses via attenuation of inflammasome activation in experimental models.
Woo-Young Shin, Do-Wan Shim, Myong-Ki Kim, Xiao Sun, Sushruta Koppula

J Ethnopharmacol· June 2017

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Juniperus rigida Sieb. extract inhibits inflammatory responses via attenuation of TRIF-dependent signaling and inflammasome activation.
Ji-Won Han, Do-Wan Shim, Woo-Young Shin, Myong-Ki Kim, Eun-Jeong Shim

J Ethnopharmacol· August 2016

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Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages.
Do-Wan Shim, Kang-Hyuck Heo, Young-Kyu Kim, Eun-Jeong Sim, Tae-Bong Kang

PLoS One· April 2016

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Cichorium intybus Linn. Extract Prevents Type 2 Diabetes Through Inhibition of NLRP3 Inflammasome Activation.
Do-Wan Shim, Ji-Won Han, Young-Eun Ji, Woo-Young Shin, Sushruta Koppula

J Med Food· March 2016

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Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress.
Yoon-Mi Lee, Gibok Lee, Taek-In Oh, Byeong Mo Kim, Do-Wan Shim

Int J Oncol· January 2016

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Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.
Na-Hyun Oh, Ji-Won Han, Do-Wan Shim, Eun-Jeong Sim, Sushruta Koppula

J Ethnopharmacol· December 2015

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Anti-inflammatory effect of Impatiens textori Miq. extract via inhibition of NLRP3 inflammasome activation in in vitro and in vivo experimental models.
Xiao Sun, Do-Wan Shim, Ji-Won Han, Woo-Young Shin, Eun-Jeong Sim

J Ethnopharmacol· July 2015

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Syneilesis palmata (Thunb.) Maxim. extract attenuates inflammatory responses via the regulation of TRIF-dependent signaling and inflammasome activation.
Ji-Won Han, Do-Wan Shim, Eun-Jeong Shim, Myong-Ki Kim, Yong-Kook Shin

J Ethnopharmacol· May 2015

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A novel synthetic derivative of melatonin, 5-hydroxy-2'-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation.
Do-Wan Shim, Hee Jae Shin, Ji-Won Han, Young-Eun Ji, Cheol-Hun Jang

Toxicol Appl Pharmacol· April 2015

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Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation.
Ji-Won Han, Do-Wan Shim, Woo-Young Shin, Kang-Hyuk Heo, Su-Bin Kwak

Int J Mol Sci· April 2015

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Anti-inflammatory effect of Streptochlorin via TRIF-dependent signaling pathways in cellular and mouse models.
Do-Wan Shim, Hee Jae Shin, Ji-Won Han, Woo-Young Shin, Xiao Sun, Eun-Jeong Shim

Int J Mol Sci· March 2015

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Streptochlorin suppresses allergic dermatitis and mast cell activation via regulation of Lyn/Fyn and Syk signaling pathways in cellular and mouse models.
Seung-Hwan Lee, Hee Jae Shin, Dong-Young Kim, Do-Wan Shim, Tack-Joong Kim

PLoS One· July 2014

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Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling.
Dong-Young Kim, Tae-Bong Kang, Do-Wan Shim, Xiao Sun, Ji-Won Han

Eur J Pharmacol· January 2014

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Lysimachia clethroides Duby extract attenuates inflammatory response in Raw 264.7 macrophages stimulated with lipopolysaccharide and in acute lung injury mouse model.
Do-Wan Shim, Ji-Won Han, Xiao Sun, Cheol-Hun Jang, Sushruta Koppula

J Ethnopharmacol· December 2013

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Carpesium macrocephalum attenuates lipopolysaccharide-induced inflammation in macrophages by regulating the NF-κB/IκB-α, Akt, and STAT signaling pathways.
Sushruta Koppula, Wan-Jae Kim, Jun Jiang, Do-Wan Shim, Na-Hyun Oh

Am J Chin Med· October 2013

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Indole-3-carbinol inhibits LPS-induced inflammatory response by blocking TRIF-dependent signaling pathway in macrophages.
Jun Jiang, Tae Bong Kang, Do Wan Shim, Na Hyun Oh, Tack Joong Kim

Food Chem Toxicol· July 2013

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