Publications by authors named "Dominick L Auci"

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Pharmacokinetics and Pharmacodynamics of Recombinant Human Interleukin 12 in Dog and Rabbit Models of Toxicity.
Benjamin D Green, Peter C Soema, Heleen Kraan, Laura Hammer, Edith Mathiowitz, Dominick L Auci

J Appl Toxicol· October 2025

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Oral Delivery of Encapsulated All-Trans Retinoic Acid Ameliorates Disease in Rodent Models of Colitis.
Ferdinando Nicoletti, Laura Hammer, Stacia Furtado, Katia Mangano, Edith Mathiowitz, Dominick L Auci

Inflamm Bowel Dis· March 2022

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Oral encapsulated transforming growth factor β1 reduces endogenous levels: Effect on inflammatory bowel disease.
Laura Hammer, Stacia Furtado, Edith Mathiowitz, Dominick L Auci

World J Gastrointest Pharmacol Ther· November 2020

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Anti-Fibrotic Potential of All Trans Retinoic Acid in Inflammatory Bowel Disease.
Dominick L Auci, Nejat K Egilmez, Gerald W Dryden

J Gastroenterol Pancreatol Liver Disord· May 2018

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Synergy of Transforming Growth Factor Beta 1 and All Trans Retinoic Acid in the Treatment of Inflammatory Bowel Disease: Role of Regulatory T cells.
Dominick L Auci, Nejat K Egilmez

J Gastroenterol Pancreatol Liver Disord· August 2016

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Oral Delivery of Particulate Transforming Growth Factor Beta 1 and All-Trans Retinoic Acid Reduces Gut Inflammation in Murine Models of Inflammatory Bowel Disease.
Thomas F Conway, Laura Hammer, Stacia Furtado, Edith Mathiowitz, Ferdinando Nicoletti, Dominick L Auci

J Crohns Colitis· August 2015

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17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.
Ferdinando Nicoletti, Ingrid Philippens, Paolo Fagone, Clarence N Ahlem, Christopher L Reading, Dominick L Auci

Parkinsons Dis· October 2012

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Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome.
Clarence N Ahlem, Dominick L Auci, Ferdinando Nicoletti, Raymond Pieters, Michael R Kennedy

J Steroid Biochem Mol Biol· September 2011

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HE3286, an orally bioavailable synthetic analogue of an active DHEA metabolite suppresses spontaneous autoimmune diabetes in the non-obese diabetic (NOD) mouse.
Michele M Kosiewicz, Dominick L Auci, Paolo Fagone, Katia Mangano, Salvatore Caponnetto

Eur J Pharmacol· May 2011

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A potential role for 5-androstene-3β,7β,17β-triol in obesity and metabolic syndrome.
Dominick L Auci, Clarence N Ahlem, Michael R Kennedy, Theodore M Page, Christopher L Reading

Obesity (Silver Spring)· April 2011

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Novel components of the human metabolome: the identification, characterization and anti-inflammatory activity of two 5-androstene tetrols.
Clarence N Ahlem, Theodore M Page, Dominick L Auci, Michael R Kennedy, Katia Mangano

Steroids· January 2011

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HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression.
Douglas Conrad, Angela Wang, Raymond Pieters, Ferdinando Nicoletti, Katia Mangano, Dominick L Auci

J Inflamm (Lond)· October 2010

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5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis.
Ajay K Malik, Sophia Khaldoyanidi, Dominick L Auci, Scott C Miller, Clarence N Ahlem

PLoS One· October 2010

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5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice.
Ferdinando Nicoletti, Dominick L Auci, Katia Mangano, Jaime Flores-Riveros, Sonia Villegas

Autoimmune Dis· May 2010

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Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis.
Dominick L Auci, Katia Mangano, Daniel Destiche, Steven K White, Yujin Huang

Int J Mol Med· April 2010

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An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis.
Halina Offner, Gary S Firestein, David L Boyle, Raymond Pieters, James M Frincke, Dominick L Auci

J Pharmacol Exp Ther· June 2009

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7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases.
Dominick L Auci, Christopher L Reading, James M Frincke

Autoimmun Rev· March 2009

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A synthetic androstene analogue inhibits collagen-induced arthritis in the mouse.
Halina Offner, Alex Zamora, Sandhya Subramanian, Magdalena Polanczyk, Aric Krogstad, Dominick L Auci

Clin Immunol· February 2004

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A synthetic androstene derivative and a natural androstene metabolite inhibit relapsing-remitting EAE.
Halina Offner, Alex Zamora, Heather Drought, Agata Matejuk, Dominick L Auci

J Neuroimmunol· September 2002

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HIV type 1-specific IgE in serum of long-term surviving children inhibits HIV type 1 production in vitro.
Michael G Pellegrino, Martin H Bluth, Tamar Smith-Norowitz, Senih Fikrig, David J Volsky, Dominick L Auci

AIDS Res Hum Retroviruses· March 2002

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