Publications by authors named "Dominik Lock"

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A novel pseudotype derived of the canine distemper virus for adapter-mediated lentiviral transduction .
Nora Winter, Carolin Kolbe, Shima Ferdos, Larissa Steiner, Nils Bartelsen, Dominik Lock

Mol Ther Methods Clin Dev· September 2025

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Automated manufacture of ΔNPM1 TCR-engineered T cells for AML therapy.
Isabella Elias Yonezawa Ogusuku, Vera Herbel, Simon Lennartz, Caroline Brandes, Eva Argiro, Dominik Lock

Mol Ther Methods Clin Dev· June 2024

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CAR'TCR-T cells co-expressing CD33-CAR and dNPM1-TCR as superior dual-targeting approach for AML treatment.
Karin Teppert, Isabella Elias Yonezawa Ogusuku, Caroline Brandes, Vera Herbel, Nora Winter, Dominik Lock

Mol Ther Oncol· June 2024

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Combining CSPG4-CAR and CD20-CCR for treatment of metastatic melanoma.
Karin Teppert, Nora Winter, Vera Herbel, Caroline Brandes, Simon Lennartz, Dominik Lock

Front Immunol· October 2023

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Targeting Stage-Specific Embryonic Antigen 4 (SSEA-4) in Triple Negative Breast Cancer by CAR T Cells Results in Unexpected on Target/off Tumor Toxicities in Mice.
Rita Pfeifer, Wa'el Al Rawashdeh, Janina Brauner, Manuel Martinez-Osuna, Dominik Lock

Int J Mol Sci· May 2023

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Combined targeting of soluble latent TGF-ß and a solid tumor-associated antigen with adapter CAR T cells.
Niels Werchau, Bettina Kotter, Elvira Criado-Moronati, Andre Gosselink, Nicole Cordes, Dominik Lock

Oncoimmunology· November 2022

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Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR".
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock

Int J Mol Sci· November 2022

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Automated, scaled, transposon-based production of CAR T cells.
Dominik Lock, Razieh Monjezi, Caroline Brandes, Stephan Bates, Simon Lennartz

J Immunother Cancer· September 2022

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Novel adapter CAR-T cell technology for precisely controllable multiplex cancer targeting.
Christian M Seitz, Joerg Mittelstaet, Daniel Atar, Jana Hau, Selina Reiter, Dominik Lock

Oncoimmunology· June 2022

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Titratable Pharmacological Regulation of CAR T Cells Using Zinc Finger-Based Transcription Factors.
Bettina Kotter, Fabian Engert, Winfried Krueger, Andre Roy, Wael Al Rawashdeh, Dominik Lock

Cancers (Basel)· September 2021

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Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells.
Nicole Cordes, Carolin Kolbe, Dominik Lock, Tatjana Holzer, Deborah Althoff

Mol Ther Methods Clin Dev· June 2021

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Automated generation of gene-edited CAR T cells at clinical scale.
Jamal Alzubi, Dominik Lock, Manuel Rhiel, Sabrina Schmitz, Stefan Wild

Mol Ther Methods Clin Dev· March 2021

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Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma.
Daniel Schäfer, Stefan Tomiuk, Laura N Küster, Wa'el Al Rawashdeh, Janina Henze, Dominik Lock

Nat Commun· March 2021

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CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from Expansion Cultures.
Anna Nowak, Dominik Lock, Petra Bacher, Thordis Hohnstein, Katrin Vogt

Front Immunol· March 2019

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Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use.
Dominik Lock, Nadine Mockel-Tenbrinck, Katharina Drechsel, Carola Barth, Daniela Mauer

Hum Gene Ther· October 2017

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FAS-based cell depletion facilitates the selective isolation of mouse induced pluripotent stem cells.
Eva Warlich, Axel Schambach, Dominik Lock, Dirk Wedekind, Silke Glage

PLoS One· March 2015

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