Publications by authors named "Dominique Burger"

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A high-resolution data set of fatty acid-binding protein structures. I. Dynamics of FABP4 and ligand binding.
Fabio Casagrande, Andreas Ehler, Dominique Burger, Joerg Benz, Alfred Ross

Acta Crystallogr D Struct Biol· August 2025

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Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy.
Maude Giroud, Bernd Kuhn, Sandra Steiner, Paul Westwood, Mateusz Mendel, Dominique Burger

J Med Chem· March 2025

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Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.
Ulrike Obst-Sander, Antonio Ricci, Bernd Kuhn, Thomas Friess, Philipp Koldewey, Dominique Burger

J Med Chem· October 2022

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Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1.
Kirsten Richter, Arne C Rufer, Magali Muller, Dominique Burger, Fabio Casagrande

J Biol Chem· July 2020

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Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
Kirsten Richter, Arne C Rufer, Magali Muller, Dominique Burger, Fabio Casagrande

J Biol Chem· June 2020

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
Hans Richter, Alexander L Satz, Marc Bedoucha, Bernd Buettelmann, Ann C Petersen, Dominique Burger

ACS Chem Biol· January 2019

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Domain swap in the C-terminal ubiquitin-like domain of human doublecortin.
Arne C Rufer, Eric Kusznir, Dominique Burger, Martine Stihle, Armin Ruf

Acta Crystallogr D Struct Biol· May 2018

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Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
Dominique Burger, Martine Stihle, Ashwani Sharma, Paola Di Lello, Jörg Benz

J Biol Chem· July 2016

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Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.
Rainer E Martin, Johannes D Aebi, Benoit Hornsperger, Hans-Jakob Krebs, Bernd Kuhn, Dominique Burger

J Med Chem· October 2015

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Inheritance of equine sarcoid disease in Franches-Montagnes horses.
Garance Christen, Vinzenz Gerber, Gaudenz Dolf, Dominique Burger, Christoph Koch

Vet J· January 2014

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Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.
David W Banner, Bernard Gsell, Jörg Benz, Julian Bertschinger, Dominique Burger

Acta Crystallogr D Biol Crystallogr· June 2013

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Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations.
Guillaume A Schoch, Brigitte D'Arcy, Martine Stihle, Dominique Burger, Dominik Bär

J Mol Biol· January 2010

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Engineering of phytase for improved activity at low pH.
Andrea Tomschy, Roland Brugger, Martin Lehmann, Allan Svendsen, Kurt Vogel, Dominique Burger

Appl Environ Microbiol· April 2002

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