Publications by authors named "Donald Bruun"

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Acute and persistent changes in neural oscillatory activity predict development of epilepsy following acute organophosphate intoxication in adult rats.
Jeremy A MacMahon, Peter M Andrew, Ali Izadi, Donald A Bruun, Naomi H Saito

Epilepsia· April 2025

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Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication.
Thomas J Blackmon, Jeremy A MacMahon, Pedro N Bernardino, Ryan E Hogans, Mei-Yun Cheng, Donald A Bruun

Acta Neuropathol Commun· March 2025

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Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate.
Peter M Andrew, Jeremy A MacMahon, Pedro N Bernardino, Yi-Hua Tsai, Brad A Hobson, Donald A Bruun

J Neuroinflammation· November 2024

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A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures.
Brad A Hobson, Douglas J Rowland, Yimeng Dou, Naomi Saito, Zachary T Harmany, Donald A Bruun

Neuropharmacology· June 2024

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Quantitative T mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication.
Alita Jesal D Almeida, Brad A Hobson, Naomi Saito, Donald A Bruun, Valerie A Porter

Neuropharmacology· May 2024

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Cardiovascular responses of adult male Sprague-Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone.
Shiyue Pan, Donald A Bruun, Pamela J Lein, Chao-Yin Chen

Arch Toxicol· April 2024

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Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain.
Yi-Hua Tsai, Eduardo A González, Ana C G Grodzki, Donald A Bruun, Naomi H Saito

Front Toxicol· April 2024

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Time- and region-dependent blood-brain barrier impairment in a rat model of organophosphate-induced status epilepticus.
Pedro N Bernardino, Brad A Hobson, Sydney L Huddleston, Peter M Andrew, Jeremy A MacMahon, Donald A Bruun

Neurobiol Dis· October 2023

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Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs.
Donald A Bruun, Betty Ma, Yi-Je Chen, Chun-Yi Wu, Monica Aleman

Epilepsia Open· June 2023

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Novel image analysis tool for rapid screening of cell morphology in preclinical animal models of disease.
Michelle Guignet, Martin Schmuck, Danielle J Harvey, Danh Nguyen, Donald Bruun

Heliyon· February 2023

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Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus.
Jonas J Calsbeek, Eduardo A González, Casey A Boosalis, Dorota Zolkowska, Donald A Bruun

Neurotoxicology· December 2021

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Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate.
Jonas J Calsbeek, Eduardo A González, Donald A Bruun, Michelle A Guignet, Nycole Copping

Neurotoxicology· December 2021

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Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos.
Elizabeth L Berg, Tianna M Ching, Donald A Bruun, Josef K Rivera, Milo Careaga

J Neurodev Disord· December 2020

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Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Suangsuda Supasai, Eduardo A González, Douglas J Rowland, Brad Hobson, Donald A Bruun

Eur J Pharmacol· November 2020

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Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats.
Ashish Dhir, Donald A Bruun, Michelle Guignet, Yi-Hua Tsai, Eduardo González

Ann N Y Acad Sci· November 2020

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Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice.
Brandon Pressly, Natalia Vasylieva, Bogdan Barnych, Vikrant Singh, Latika Singh, Donald A Bruun

Arch Toxicol· June 2020

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The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity.
Eduardo A González, Alexa C Rindy, Michelle A Guignet, Jonas J Calsbeek, Donald A Bruun

Arch Toxicol· June 2020

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Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication.
Michelle Guignet, Kiran Dhakal, Brenna M Flannery, Brad A Hobson, Dorota Zolkowska, Donald A Bruun

Neurobiol Dis· January 2020

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Lipidomes of brain from rats acutely intoxicated with diisopropylfluorophosphate identifies potential therapeutic targets.
Jun Yang, Donald A Bruun, Chang Wang, Debin Wan, Cindy B McReynolds

Toxicol Appl Pharmacol· November 2019

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TSPO PET Using [18F]PBR111 Reveals Persistent Neuroinflammation Following Acute Diisopropylfluorophosphate Intoxication in the Rat.
Brad A Hobson, Douglas J Rowland, Sílvia Sisó, Michelle A Guignet, Zachary T Harmany, Donald A Bruun

Toxicol Sci· August 2019

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Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
Donald A Bruun, Michelle Guignet, Danielle J Harvey, Pamela J Lein

Neurotoxicology· July 2019

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The Use of Percent Change in RR Interval for Data Exclusion in Analyzing 24-h Time Domain Heart Rate Variability in Rodents.
Emma Karey, Shiyue Pan, Amber N Morris, Donald A Bruun, Pamela J Lein

Front Physiol· June 2019

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From the Cover: MagneticResonance Imaging Reveals Progressive Brain Injury in Rats Acutely Intoxicated With Diisopropylfluorophosphate.
Brad A Hobson, Sílvia Sisó, Douglas J Rowland, Danielle J Harvey, Donald A Bruun

Toxicol Sci· June 2017

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Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate.
Sílvia Sisó, Brad A Hobson, Danielle J Harvey, Donald A Bruun, Douglas J Rowland

Toxicol Sci· June 2017

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Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis.
Carlos Antonio Trindade-da-Silva, Ahmed Bettaieb, Marcelo Henrique Napimoga, Kin Sing Stephen Lee, Bora Inceoglu, Donald Bruun

J Pharmacol Exp Ther· June 2017

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