Publications by authors named "Donald D Newmeyer"

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Targeting Ca and Mitochondrial Homeostasis by Antipsychotic Thioridazine in Leukemia Cells.
Vivian W R Moraes, Vivian M Santos, Eloah R Suarez, Letícia S Ferraz, Rayssa de Mello Lopes, Donald D Newmeyer

Life (Basel)· September 2022

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Disruption of mitochondrial quality control genes promotes caspase-resistant cell survival following apoptotic stimuli.
Yulia Kushnareva, Vivian Moraes, Julian Suess, Bjoern Peters, Donald D Newmeyer

J Biol Chem· April 2022

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Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization.
Tomomi Kuwana, Louise E King, Katia Cosentino, Julian Suess, Ana J Garcia-Saez, Donald D Newmeyer

J Biol Chem· February 2020

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Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1.
Tong Liu, Tomomi Kuwana, Hongkai Zhang, Matthew G Vander Heiden, Richard A Lerner, Donald D Newmeyer

PLoS Biol· June 2019

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Pro-apoptotic Bax molecules densely populate the edges of membrane pores.
Tomomi Kuwana, Norman H Olson, William B Kiosses, Bjoern Peters, Donald D Newmeyer

Sci Rep· June 2016

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Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes.
Laura A Gillies, Han Du, Bjoern Peters, C Michael Knudson, Donald D Newmeyer

Mol Biol Cell· January 2015

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Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis.
Thibaud T Renault, Konstantinos V Floros, Rana Elkholi, Kelly-Ann Corrigan, Yulia Kushnareva, Donald D Newmeyer

Mol Cell· January 2015

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Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes.
Yulia Kushnareva, Alexander Y Andreyev, Tomomi Kuwana, Donald D Newmeyer

PLoS Biol· June 2013

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Bioenergetics and cell death.
Yulia Kushnareva, Donald D Newmeyer

Ann N Y Acad Sci· July 2010

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Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release.
Lydia Lartigue, Yulia Kushnareva, Youngmo Seong, Helen Lin, Benjamin Faustin, Donald D Newmeyer

Mol Biol Cell· December 2009

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Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
Ryuji Yamaguchi, Lydia Lartigue, Guy Perkins, Ray T Scott, Amruta Dixit, Donald D Newmeyer

Mol Cell· August 2008

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GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.
Anna Colell, Jean-Ehrland Ricci, Stephen Tait, Sandra Milasta, Ulrich Maurer, Donald D Newmeyer

Cell· June 2007

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Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.
Cristina Muñoz-Pinedo, Ana Guío-Carrión, Joshua C Goldstein, Patrick Fitzgerald, Donald D Newmeyer

Proc Natl Acad Sci U S A· August 2006

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Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.
Christine Bonzon, Lisa Bouchier-Hayes, Lisa J Pagliari, Douglas R Green, Donald D Newmeyer

Mol Biol Cell· May 2006

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The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.
Lisa J Pagliari, Tomomi Kuwana, Christine Bonzon, Donald D Newmeyer, Shine Tu

Proc Natl Acad Sci U S A· December 2005

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Mitochondria: pharmacological manipulation of cell death.
Lisa Bouchier-Hayes, Lydia Lartigue, Donald D Newmeyer

J Clin Invest· October 2005

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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
Jerry E Chipuk, Lisa Bouchier-Hayes, Tomomi Kuwana, Donald D Newmeyer, Douglas R Green

Science· September 2005

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BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Tomomi Kuwana, Lisa Bouchier-Hayes, Jerry E Chipuk, Christine Bonzon, Barbara A Sullivan, Donald D Newmeyer

Mol Cell· February 2005

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Mitochondrial release of pro-apoptotic proteins: electrostatic interactions can hold cytochrome c but not Smac/DIABLO to mitochondrial membranes.
Rachel T Uren, Grant Dewson, Christine Bonzon, Trevor Lithgow, Donald D Newmeyer

J Biol Chem· January 2005

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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
Jerry E Chipuk, Tomomi Kuwana, Lisa Bouchier-Hayes, Nathalie M Droin, Donald D Newmeyer

Science· February 2004

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Bcl-2-family proteins and the role of mitochondria in apoptosis.
Tomomi Kuwana, Donald D Newmeyer

Curr Opin Cell Biol· December 2003

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Mitochondria: releasing power for life and unleashing the machineries of death.
Donald D Newmeyer, Shelagh Ferguson-Miller

Cell· February 2003

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.
Tomomi Kuwana, Mason R Mackey, Guy Perkins, Mark H Ellisman, Martin Latterich, Donald D Newmeyer

Cell· November 2002

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A cytochrome c mutant with high electron transfer and antioxidant activities but devoid of apoptogenic effect.
Ziedulla Kh Abdullaev, Marina E Bodrova, Boris V Chernyak, Dmitry A Dolgikh, Ruth M Kluck, Donald D Newmeyer

Biochem J· March 2002

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