Publications by authors named "Donald Jung"

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Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys.
Teng Meng, Donald Jung, Xiao-Hong Cai, Zhao-Qiang Lu, Ji-Bing Yu

Biopharm Drug Dispos· April 2024

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Erratum: A novel selective AKR1C3-activated prodrug AST-3424/OBI-3424 exhibits broad anti-tumor activity.
Fanying Meng, Wan-Fen Li, Donald Jung, Chun-Chung Wang, Tianyang Qi

Am J Cancer Res· November 2023

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A novel selective AKR1C3-activated prodrug AST-3424/OBI-3424 exhibits broad anti-tumor activity.
Fanying Meng, Wan-Fen Li, Donald Jung, Chun-Chung Wang, Tianyang Qi

Am J Cancer Res· July 2021

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OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL.
Kathryn Evans, JianXin Duan, Tara Pritchard, Connor D Jones, Lisa McDermott, Donald Jung

Clin Cancer Res· July 2019

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Pharmacodynamic evaluation of intragastric pH and implications for famotidine dosing in the prophylaxis of non-steroidal anti-inflammatory drug induced gastropathy-a proof of concept analysis.
Jeffery D Kent, Robert J Holt, Donald Jung, George F Tidmarsh, Amy Y Grahn

J Drug Assess· August 2016

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Mass balance and metabolism of the antimalarial pyronaridine in healthy volunteers.
Carrie A Morris, Stephen R Dueker, Peter N Lohstroh, Li-Quan Wang, Xin-Ping Fang, Donald Jung

Eur J Drug Metab Pharmacokinet· March 2015

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Effects of body size and gender on the population pharmacokinetics of artesunate and its active metabolite dihydroartemisinin in pediatric malaria patients.
Carrie A Morris, Beesan Tan, Stephan Duparc, Isabelle Borghini-Fuhrer, Donald Jung

Antimicrob Agents Chemother· December 2013

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A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors.
Luis E Raez, Kyriakos Papadopoulos, Alejandro D Ricart, E Gabriella Chiorean, Robert S Dipaola, Donald T Jung

Cancer Chemother Pharmacol· February 2013

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Metabolism and excretion of TH-302 in dogs.
Donald Jung, Hailong Jiao, Jian-Xi Duan, Mark Matteucci, Ronghua Wang

Xenobiotica· July 2012

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Metabolism, pharmacokinetics and excretion of a novel hypoxia activated cytotoxic prodrug, TH-302, in rats.
Donald Jung, Hailong Jiao, Jian-Xi Duan, Mark Matteucci, Ronghua Wang

Xenobiotica· April 2012

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Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys.
Donald Jung, Lin Lin, Hailong Jiao, Xiaohong Cai, Jian-Xin Duan

Cancer Chemother Pharmacol· March 2012

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Drug-drug interaction analysis of pyronaridine/artesunate and ritonavir in healthy volunteers.
Carrie A Morris, Luis Lopez-Lazaro, Donald Jung, Janthima Methaneethorn, Stephan Duparc

Am J Trop Med Hyg· March 2012

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Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration.
Carrie A Morris, Stephan Duparc, Isabelle Borghini-Fuhrer, Donald Jung, Chang-Sik Shin

Malar J· September 2011

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14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment.
Jian-Xin Duan, Xiaohong Cai, Fanying Meng, Jessica D Sun, Qian Liu, Donald Jung, Brian Jung

J Med Chem· March 2011

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A phase 2 trial of glufosfamide in combination with gemcitabine in chemotherapy-naive pancreatic adenocarcinoma.
Elena G Chiorean, Tomislav Dragovich, John Hamm, Carlos H Barrios, Carlos F Gorini, Donald T Jung

Am J Clin Oncol· April 2010

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A Phase 1 dose-escalation trial of glufosfamide in combination with gemcitabine in solid tumors including pancreatic adenocarcinoma.
E Gabriela Chiorean, Tomislav Dragovich, John Hamm, Virginia K Langmuir, Stewart Kroll, Donald T Jung

Cancer Chemother Pharmacol· May 2008

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Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Edzard Schwedhelm, Renke Maas, Ralf Freese, Donald Jung, Zoltan Lukacs

Br J Clin Pharmacol· January 2008

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Pre-clinical and clinical evaluation of solution and soft gelatin capsule formulations for a BCS class 3 compound with atypical physicochemical properties.
Karen Ramsay-Olocco, Ludmila Alexandrova, Ranjani Nellore, Robert Killion, Li Li, Donald Jung

J Pharm Sci· September 2004

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High dose oral ganciclovir treatment for cytomegalovirus retinitis.
Jacob P Lalezari, Dorothy N Friedberg, Jack Bissett, Michael F Giordano, W David Hardy, Donald T Jung

J Clin Virol· February 2002

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